22 items (Physeter catodon) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Your Input:
	ADSL	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (514 aa)
	AK4	Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa)
	ADK	Adenosine kinase isoform X5. (362 aa)
	AMPD2	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (799 aa)
	ENSPCTP00005023524	annotation not available (222 aa)
	NT5E	5'-nucleotidase; Belongs to the 5'-nucleotidase family. (574 aa)
	ADA	Adenosine deaminase isoform X2. (352 aa)
	URAD	LOW QUALITY PROTEIN: putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. (167 aa)
	PFAS	Phosphoribosylformylglycinamidine synthase isoform X2. (1338 aa)
	LOC102983042	Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (299 aa)
	ATIC	Bifunctional purine biosynthesis protein PURH. (592 aa)
	XDH	Xanthine dehydrogenase/oxidase. (219 aa)
	AK1	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (211 aa)
	ADSS1	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
	APRT	Adenine phosphoribosyltransferase isoform X2. (180 aa)
	AK3	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (227 aa)
	PPAT	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (540 aa)
	NUDT2	Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Belongs to the Nudix hydrolase family. (147 aa)
	NT5C1A	Cytosolic 5'-nucleotidase 1A. (365 aa)
	AMPD1	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (779 aa)
	ENSPCTP00005001421	annotation not available (162 aa)
	ADSS	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa)

Your Current Organism:

Physeter catodon

NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADA	ADK	ENSPCTP00005021172	ENSPCTP00005028593	Adenosine deaminase isoform X2.	Adenosine kinase isoform X5.	0.841
ADA	ADSL	ENSPCTP00005021172	ENSPCTP00005014883	Adenosine deaminase isoform X2.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.402
ADA	AMPD1	ENSPCTP00005021172	ENSPCTP00005001488	Adenosine deaminase isoform X2.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.546
ADA	AMPD2	ENSPCTP00005021172	ENSPCTP00005025423	Adenosine deaminase isoform X2.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.568
ADA	APRT	ENSPCTP00005021172	ENSPCTP00005008911	Adenosine deaminase isoform X2.	Adenine phosphoribosyltransferase isoform X2.	0.878
ADA	LOC102983042	ENSPCTP00005021172	ENSPCTP00005017790	Adenosine deaminase isoform X2.	Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family.	0.494
ADA	NT5E	ENSPCTP00005021172	ENSPCTP00005023155	Adenosine deaminase isoform X2.	5'-nucleotidase; Belongs to the 5'-nucleotidase family.	0.787
ADK	ADA	ENSPCTP00005028593	ENSPCTP00005021172	Adenosine kinase isoform X5.	Adenosine deaminase isoform X2.	0.841
ADK	ADSL	ENSPCTP00005028593	ENSPCTP00005014883	Adenosine kinase isoform X5.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.959
ADK	ADSS	ENSPCTP00005028593	ENSPCTP00005001181	Adenosine kinase isoform X5.	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.478
ADK	ADSS1	ENSPCTP00005028593	ENSPCTP00005009464	Adenosine kinase isoform X5.	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.431
ADK	AK1	ENSPCTP00005028593	ENSPCTP00005011895	Adenosine kinase isoform X5.	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.	0.945
ADK	AK3	ENSPCTP00005028593	ENSPCTP00005007926	Adenosine kinase isoform X5.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.946
ADK	AK4	ENSPCTP00005028593	ENSPCTP00005031894	Adenosine kinase isoform X5.	Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.	0.924
ADK	AMPD1	ENSPCTP00005028593	ENSPCTP00005001488	Adenosine kinase isoform X5.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.958
ADK	AMPD2	ENSPCTP00005028593	ENSPCTP00005025423	Adenosine kinase isoform X5.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.966
ADK	APRT	ENSPCTP00005028593	ENSPCTP00005008911	Adenosine kinase isoform X5.	Adenine phosphoribosyltransferase isoform X2.	0.981
ADK	ATIC	ENSPCTP00005028593	ENSPCTP00005014693	Adenosine kinase isoform X5.	Bifunctional purine biosynthesis protein PURH.	0.806
ADK	ENSPCTP00005001421	ENSPCTP00005028593	ENSPCTP00005001421	Adenosine kinase isoform X5.	annotation not available	0.485
ADK	ENSPCTP00005023524	ENSPCTP00005028593	ENSPCTP00005023524	Adenosine kinase isoform X5.	annotation not available	0.431