STRINGSTRING
A4GNT A4GNT IFT80 IFT80 CAV1 CAV1 CAV2 CAV2 PDCD10 PDCD10 ENSPCTP00005001136 ENSPCTP00005001136 AIMP1 AIMP1 LIMS2 LIMS2 B4GALT1 B4GALT1 CDC73 CDC73 SYNJ2BP SYNJ2BP KRIT1 KRIT1 WDR77 WDR77 TGFB2 TGFB2 TRIM24 TRIM24 CDK6 CDK6 IL12B IL12B ENSPCTP00005004128 ENSPCTP00005004128 IL26 IL26 IFT57 IFT57 DUSP10-2 DUSP10-2 SFRP2 SFRP2 DLG1 DLG1 ZEB1 ZEB1 KLF9 KLF9 GATA3 GATA3 IL12A IL12A NGFR NGFR TNMD TNMD PTCH1 PTCH1 ATOH8 ATOH8 STK3 STK3 CNMD CNMD MEF2C MEF2C FGFR3 FGFR3 WDR13 WDR13 AR AR MMRN2 MMRN2 GHRL GHRL MED1 MED1 PTPRK PTPRK GDF5 GDF5 SOX9 SOX9 GDF2 GDF2 OVOL1 OVOL1 ATP5F1A ATP5F1A EAF2 EAF2 MTSS1 MTSS1 ENSPCTP00005011984 ENSPCTP00005011984 APOH APOH MARVELD3 MARVELD3 NOTCH1 NOTCH1 XDH XDH DLG2 DLG2 TBC1D31 TBC1D31 LOC112064560 LOC112064560 PEX2 PEX2 NKX2-8 NKX2-8 PTPRM PTPRM TGFBR1 TGFBR1 NF1 NF1 INTU INTU SNAI2 SNAI2 SFRP1 SFRP1 NFIB NFIB SERPINF1 SERPINF1 NR2F2 NR2F2 AQP11 AQP11 PHOX2B PHOX2B LOC114486517 LOC114486517 CCL2 CCL2 COL4A3 COL4A3 PAX6 PAX6 PDX1 PDX1 LOC102985248 LOC102985248 SLURP1 SLURP1 LOC102995227 LOC102995227 SULF1 SULF1 SAV1 SAV1 FLT1 FLT1 STK4 STK4 HPN HPN ACVRL1 ACVRL1 KRT4 KRT4 NKX3-1 NKX3-1 WNT10B WNT10B LOC112067463 LOC112067463 ENSPCTP00005022980 ENSPCTP00005022980 KDF1 KDF1 CDKN2A CDKN2A CDKN2B CDKN2B SFN SFN TGFB1 TGFB1 IFT74 IFT74 BRCA2 BRCA2 RB1 RB1 DUSP10 DUSP10 APOE APOE CDKN1B CDKN1B GPC3 GPC3 DAB2IP DAB2IP NUPR1 NUPR1 ROBO1 ROBO1 STAT1 STAT1 DLL4 DLL4 PHB2 PHB2 LOC102985024 LOC102985024 MCC MCC CASK CASK LOC114485528 LOC114485528 THBS1 THBS1 STK11 STK11 DRD2 DRD2 IRF6 IRF6 TINF2 TINF2 IFT52 IFT52 MAGED1 MAGED1 WNT5A WNT5A FGFR2 FGFR2 CD109 CD109 PPARD PPARD BMP4 BMP4 VASH1 VASH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A4GNTalpha-1,4-N-acetylglucosaminyltransferase. (341 aa)
IFT80Intraflagellar transport protein 80 homolog. (777 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
PDCD10Programmed cell death protein 10. (212 aa)
ENSPCTP00005001136annotation not available (90 aa)
AIMP1Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 isoform X1. (305 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (366 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (404 aa)
CDC73Parafibromin. (531 aa)
SYNJ2BPSynaptojanin-2-binding protein isoform X2. (145 aa)
KRIT1Krev interaction trapped protein 1. (736 aa)
WDR77Methylosome protein 50 isoform X1. (342 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TRIM24Transcription intermediary factor 1-alpha isoform X1. (1052 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)
ENSPCTP00005004128annotation not available (95 aa)
IL26LOW QUALITY PROTEIN: interleukin-26. (171 aa)
IFT57Intraflagellar transport protein 57 homolog. (427 aa)
DUSP10-2Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (177 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
DLG1Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (927 aa)
ZEB1Zinc finger E-box-binding homeobox 1 isoform X2. (1125 aa)
KLF9Krueppel-like factor 9 isoform X1. (244 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
TNMDTenomodulin. (317 aa)
PTCH1Protein patched homolog 1. (1449 aa)
ATOH8Protein atonal homolog 8 isoform X4. (317 aa)
STK3Serine/threonine-protein kinase 3 isoform X2. (491 aa)
CNMDLeukocyte cell-derived chemotaxin 1. (335 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (483 aa)
FGFR3Fibroblast growth factor receptor. (805 aa)
WDR13WD repeat-containing protein 13 isoform X1. (485 aa)
ARAndrogen receptor isoform X1. (892 aa)
MMRN2Multimerin-2 isoform X1. (933 aa)
GHRLLOW QUALITY PROTEIN: appetite-regulating hormone. (115 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
PTPRKReceptor-type tyrosine-protein phosphatase kappa isoform X1. (1471 aa)
GDF5Growth/differentiation factor 5. (499 aa)
SOX9Transcription factor SOX-9. (501 aa)
GDF2Growth/differentiation factor 2. (432 aa)
OVOL1Putative transcription factor Ovo-like 1. (267 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa)
EAF2ELL-associated factor 2. (264 aa)
MTSS1Metastasis suppressor protein 1 isoform X5. (760 aa)
ENSPCTP00005011984annotation not available (66 aa)
APOHBeta-2-glycoprotein 1. (345 aa)
MARVELD3MARVEL domain-containing protein 3. (384 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2531 aa)
XDHXanthine dehydrogenase/oxidase. (219 aa)
DLG2Disks large homolog 2 isoform X2. (904 aa)
TBC1D31TBC1 domain family member 31 isoform X1. (1061 aa)
LOC112064560Synaptojanin-2-binding protein-like. (142 aa)
PEX2Peroxisome biogenesis factor 2 isoform X2. (305 aa)
NKX2-8Homeobox protein Nkx-2.8. (235 aa)
PTPRMReceptor-type tyrosine-protein phosphatase mu isoform X5. (1465 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (513 aa)
NF1Neurofibromin isoform X3. (2860 aa)
INTUProtein inturned isoform X1. (934 aa)
SNAI2Zinc finger protein SNAI2. (268 aa)
SFRP1Secreted frizzled-related protein 1. (307 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
SERPINF1Pigment epithelium-derived factor; Belongs to the serpin family. (437 aa)
NR2F2COUP transcription factor 2 isoform X1. (489 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (251 aa)
PHOX2BPaired mesoderm homeobox protein 2B. (314 aa)
LOC114486517Vitamin D3 receptor-like. (144 aa)
CCL2Monocyte chemotactic protein 1B. (98 aa)
COL4A3Collagen alpha-3(IV) chain. (1670 aa)
PAX6Paired box protein Pax-6 isoform X1. (436 aa)
PDX1Pancreas/duodenum homeobox protein 1. (283 aa)
LOC102985248Mucin-16. (246 aa)
SLURP1Secreted Ly-6/uPAR-related protein 1. (104 aa)
LOC102995227Folliculin isoform X1. (478 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (868 aa)
SAV1Protein salvador homolog 1. (384 aa)
FLT1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
STK4Serine/threonine-protein kinase 4. (448 aa)
HPNSerine protease hepsin; Belongs to the peptidase S1 family. (417 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
KRT4Keratin, type II cytoskeletal 4; Belongs to the intermediate filament family. (520 aa)
NKX3-1Homeobox protein Nkx-3.1. (158 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LOC112067463Cyclin-dependent kinase inhibitor 1C-like. (269 aa)
ENSPCTP00005022980annotation not available (174 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
CDKN2ACyclin-dependent kinase inhibitor 2A-like isoform X1. (156 aa)
CDKN2BCyclin-dependent kinase 4 inhibitor B isoform X1. (138 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
IFT74Intraflagellar transport protein 74 homolog isoform X1. (600 aa)
BRCA2LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein. (3429 aa)
RB1Retinoblastoma-associated protein isoform X2. (929 aa)
DUSP10Dual specificity phosphatase 10. (292 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
GPC3Glypican-3 isoform X1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
DAB2IPDisabled homolog 2-interacting protein. (1112 aa)
NUPR1Nuclear protein 1. (82 aa)
ROBO1Roundabout homolog 1. (1649 aa)
STAT1Signal transducer and activator of transcription. (749 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
PHB2Prohibitin. (299 aa)
LOC102985024Vitamin D3 receptor. (318 aa)
MCCColorectal mutant cancer protein. (1016 aa)
CASKPeripheral plasma membrane protein CASK isoform X2; Belongs to the MAGUK family. (962 aa)
LOC114485528Arachidonate 5-lipoxygenase-like. (367 aa)
THBS1Thrombospondin-1. (1198 aa)
STK11Serine/threonine-protein kinase STK11 isoform X4; Belongs to the protein kinase superfamily. (437 aa)
DRD2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (443 aa)
IRF6Interferon regulatory factor 6 isoform X1. (473 aa)
TINF2TERF1-interacting nuclear factor 2. (465 aa)
IFT52Intraflagellar transport protein 52 homolog isoform X1. (446 aa)
MAGED1Melanoma-associated antigen D1. (884 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
CD109CD109 antigen isoform X1. (1440 aa)
PPARDPeroxisome proliferator-activated receptor delta. (441 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
VASH1tubulinyl-Tyr carboxypeptidase 1 isoform X1. (363 aa)
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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