(47 nodes) FERM superfamily, second domain network (Physeter catodon)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FARP1	FERM, ARHGEF and pleckstrin domain-containing protein 1 isoform X2. (1120 aa)
	FRMD4A	FERM domain-containing protein 4A isoform X2. (993 aa)
	TLN2	Talin-2. (2486 aa)
	FRMD4B	FERM domain-containing protein 4B isoform X1. (1035 aa)
	PTPN21	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1179 aa)
	FERMT1	Fermitin family homolog 1 isoform X1. (677 aa)
	EPB41L5	Band 4.1-like protein 5 isoform X1. (726 aa)
	FRMPD3	FERM and PDZ domain-containing protein 3. (1765 aa)
	FRMPD2	FERM and PDZ domain-containing protein 2. (1393 aa)
	FRMD5	FERM domain-containing protein 5 isoform X1. (570 aa)
	FRMD7	FERM domain-containing protein 7. (703 aa)
	FRMD8	FERM domain-containing protein 8. (465 aa)
	PTK2	Focal adhesion kinase 1 isoform X10; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
	EPB41L4B	Band 4.1-like protein 4B isoform X2. (863 aa)
	LOC114485433	Unconventional myosin-VIIa-like. (751 aa)
	FRMPD1	FERM and PDZ domain-containing protein 1. (1576 aa)
	PTPN3	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (944 aa)
	FRMPD4	FERM and PDZ domain-containing protein 4. (1779 aa)
	PLEKHH1	Pleckstrin homology domain-containing family H member 1 isoform X2. (1352 aa)
	FARP2	FERM, ARHGEF and pleckstrin domain-containing protein 2 isoform X3. (615 aa)
	EPB41L3	Band 4.1-like protein 3. (760 aa)
	FERMT3	Fermitin family homolog 3. (667 aa)
	TLN1	Talin-1 isoform X2. (2291 aa)
	FRMD6	FERM domain-containing protein 6 isoform X1. (622 aa)
	TYK2	Tyrosine-protein kinase. (1185 aa)
	FERMT2	Fermitin family homolog 2 isoform X3. (698 aa)
	JAK1	Tyrosine-protein kinase. (1154 aa)
	EPB41L4A	Band 4.1-like protein 4A isoform X1. (686 aa)
	PTPN13	Tyrosine-protein phosphatase non-receptor type 13 isoform X1. (2493 aa)
	MYO7B	Unconventional myosin-VIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2117 aa)
	PTK2B	Protein-tyrosine kinase 2-beta isoform X3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
	KRIT1	Krev interaction trapped protein 1. (736 aa)
	PLEKHH2	Pleckstrin homology domain-containing family H member 2 isoform X1. (1487 aa)
	EPB41L1	Band 4.1-like protein 1 isoform X7. (881 aa)
	MYO15B	LOW QUALITY PROTEIN: myosin XVB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1437 aa)
	EPB41L2	Band 4.1-like protein 2 isoform X7. (1083 aa)
	MSN	Moesin isoform X1. (674 aa)
	NF2	Merlin. (541 aa)
	JAK2	Tyrosine-protein kinase. (1132 aa)
	RDX	Radixin isoform X1. (604 aa)
	MYLIP	E3 ubiquitin-protein ligase MYLIP. (445 aa)
	EPB41	Protein 4.1 isoform X9. (841 aa)
	PTPN14	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1187 aa)
	EZR	Ezrin isoform X1. (586 aa)
	MYO10	Unconventional myosin-X isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1958 aa)
	FRMD3	FERM domain-containing protein 3. (597 aa)
	PTPN4	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (928 aa)

Your Current Organism:

Physeter catodon

NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EPB41	EPB41L1	ENSPCTP00005005364	ENSPCTP00005009478	Protein 4.1 isoform X9.	Band 4.1-like protein 1 isoform X7.	0.433
EPB41	EPB41L2	ENSPCTP00005005364	ENSPCTP00005009193	Protein 4.1 isoform X9.	Band 4.1-like protein 2 isoform X7.	0.413
EPB41	EPB41L3	ENSPCTP00005005364	ENSPCTP00005019115	Protein 4.1 isoform X9.	Band 4.1-like protein 3.	0.482
EPB41	EPB41L5	ENSPCTP00005005364	ENSPCTP00005004335	Protein 4.1 isoform X9.	Band 4.1-like protein 5 isoform X1.	0.488
EPB41	EZR	ENSPCTP00005005364	ENSPCTP00005004834	Protein 4.1 isoform X9.	Ezrin isoform X1.	0.666
EPB41	MSN	ENSPCTP00005005364	ENSPCTP00005008763	Protein 4.1 isoform X9.	Moesin isoform X1.	0.444
EPB41	RDX	ENSPCTP00005005364	ENSPCTP00005006634	Protein 4.1 isoform X9.	Radixin isoform X1.	0.555
EPB41L1	EPB41	ENSPCTP00005009478	ENSPCTP00005005364	Band 4.1-like protein 1 isoform X7.	Protein 4.1 isoform X9.	0.433
EPB41L1	EPB41L2	ENSPCTP00005009478	ENSPCTP00005009193	Band 4.1-like protein 1 isoform X7.	Band 4.1-like protein 2 isoform X7.	0.653
EPB41L1	EPB41L3	ENSPCTP00005009478	ENSPCTP00005019115	Band 4.1-like protein 1 isoform X7.	Band 4.1-like protein 3.	0.526
EPB41L1	EZR	ENSPCTP00005009478	ENSPCTP00005004834	Band 4.1-like protein 1 isoform X7.	Ezrin isoform X1.	0.548
EPB41L1	MSN	ENSPCTP00005009478	ENSPCTP00005008763	Band 4.1-like protein 1 isoform X7.	Moesin isoform X1.	0.529
EPB41L1	RDX	ENSPCTP00005009478	ENSPCTP00005006634	Band 4.1-like protein 1 isoform X7.	Radixin isoform X1.	0.529
EPB41L2	EPB41	ENSPCTP00005009193	ENSPCTP00005005364	Band 4.1-like protein 2 isoform X7.	Protein 4.1 isoform X9.	0.413
EPB41L2	EPB41L1	ENSPCTP00005009193	ENSPCTP00005009478	Band 4.1-like protein 2 isoform X7.	Band 4.1-like protein 1 isoform X7.	0.653
EPB41L2	EPB41L3	ENSPCTP00005009193	ENSPCTP00005019115	Band 4.1-like protein 2 isoform X7.	Band 4.1-like protein 3.	0.623
EPB41L3	EPB41	ENSPCTP00005019115	ENSPCTP00005005364	Band 4.1-like protein 3.	Protein 4.1 isoform X9.	0.482
EPB41L3	EPB41L1	ENSPCTP00005019115	ENSPCTP00005009478	Band 4.1-like protein 3.	Band 4.1-like protein 1 isoform X7.	0.526
EPB41L3	EPB41L2	ENSPCTP00005019115	ENSPCTP00005009193	Band 4.1-like protein 3.	Band 4.1-like protein 2 isoform X7.	0.623
EPB41L5	EPB41	ENSPCTP00005004335	ENSPCTP00005005364	Band 4.1-like protein 5 isoform X1.	Protein 4.1 isoform X9.	0.488