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| | GLRX2 | Glutaredoxin 2 isoform X1. (166 aa) |
| | GART | Trifunctional purine biosynthetic protein adenosine-3. (437 aa) |
| | CEP44 | Centrosomal protein of 44 kDa isoform X1. (459 aa) |
| | GMPS | GMP synthase [glutamine-hydrolyzing]. (693 aa) |
| | LOC102975756 | Hypoxanthine-guanine phosphoribosyltransferase-like. (227 aa) |
| | DCK | Deoxycytidine kinase isoform X1. (376 aa) |
| | PNP | Purine nucleoside phosphorylase. (96 aa) |
| | NUDT9 | ADP-ribose pyrophosphatase, mitochondrial isoform X1. (350 aa) |
| | ENSPCTP00005003046 | annotation not available (114 aa) |
| | GDA | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (472 aa) |
| | DPYD | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa) |
| | UCK2 | Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa) |
| | ENSPCTP00005002743 | annotation not available (205 aa) |
| | IMPDH1 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (571 aa) |
| | GUK1 | Guanylate kinase isoform X4. (198 aa) |
| | NT5C1A | Cytosolic 5'-nucleotidase 1A. (365 aa) |
| | AMPD1 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (779 aa) |
| | ENSPCTP00005001205 | annotation not available (74 aa) |
| | ADSS | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa) |
| | SMIM3 | Small integral membrane protein 3. (60 aa) |
| | PRTFDC1 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (225 aa) |
| | ENKUR | Enkurin isoform X1. (255 aa) |
| | AK6 | Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa) |
| | CTPS1 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (700 aa) |
| | ENSPCTP00005000539 | annotation not available (286 aa) |
| | ENSPCTP00005000448 | annotation not available (191 aa) |
| | ENSPCTP00005000408 | annotation not available (218 aa) |
| | AK2 | Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (241 aa) |
| | NUDT16 | U8 snoRNA-decapping enzyme. (195 aa) |
| | NME9 | Thioredoxin domain-containing protein 6 isoform X1; Belongs to the NDK family. (329 aa) |
| | LOC112062886 | Nucleoside diphosphate kinase. (154 aa) |
| | LOC114484769 | Adenylate kinase 4-like; Belongs to the adenylate kinase family. (143 aa) |
| | AK4 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa) |
| | NME4 | Nucleoside diphosphate kinase. (187 aa) |
| | ENSPCTP00005031685 | annotation not available (290 aa) |
| | NUDT18 | 8-oxo-dGDP phosphatase NUDT18 isoform X1. (323 aa) |
| | ENTPD1 | Ectonucleoside triphosphate diphosphohydrolase 1 isoform X1; Belongs to the GDA1/CD39 NTPase family. (513 aa) |
| | ENTPD5 | Ectonucleoside triphosphate diphosphohydrolase 5 isoform X1; Belongs to the GDA1/CD39 NTPase family. (428 aa) |
| | TXNDC2 | Thioredoxin domain-containing protein 2. (79 aa) |
| | DALRD3 | DALR anticodon-binding domain-containing protein 3 isoform X5. (539 aa) |
| | IMPDH2 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa) |
| | LOC102989831 | Glutamine-rich protein 1. (313 aa) |
| | GMPR2 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (340 aa) |
| | ADAL | LOW QUALITY PROTEIN: adenosine deaminase-like protein. (354 aa) |
| | NUDT1 | 7,8-dihydro-8-oxoguanine triphosphatase; Belongs to the Nudix hydrolase family. (156 aa) |
| | ENSPCTP00005030070 | annotation not available (142 aa) |
| | LOC102984303 | Thioredoxin; Belongs to the thioredoxin family. (105 aa) |
| | AK7 | Adenylate kinase 7 isoform X1. (722 aa) |
| | ENSPCTP00005029477 | annotation not available (112 aa) |
| | UPB1 | Beta-ureidopropionase. (378 aa) |
| | NT5C2 | Cytosolic purine 5'-nucleotidase isoform X1. (573 aa) |
| | GSR | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (519 aa) |
| | ADK | Adenosine kinase isoform X5. (362 aa) |
| | RRM1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (791 aa) |
| | DPYS | Dihydropyrimidinase isoform X1. (519 aa) |
| | TK1 | Thymidine kinase. (266 aa) |
| | TXNRD3 | LOW QUALITY PROTEIN: thioredoxin reductase 3. (611 aa) |
| | DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. (232 aa) |
| | DHODH | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (395 aa) |
| | LOC102985101 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa) |
| | SLC25A42 | Mitochondrial coenzyme A transporter SLC25A42 isoform X2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (364 aa) |
| | TXNRD1 | Thioredoxin reductase 1, cytoplasmic isoform X3. (565 aa) |
| | LOC102992058 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa) |
| | LOC112062729 | Uridine phosphorylase 1-like. (169 aa) |
| | TYMS | Thymidylate synthase. (315 aa) |
| | NUDT16L1 | Tudor-interacting repair regulator protein isoform X1. (211 aa) |
| | ENTPD3 | Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (529 aa) |
| | AMPD2 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (799 aa) |
| | LOC112065412 | LOW QUALITY PROTEIN: nucleotide triphosphate diphosphatase NUDT15-like. (165 aa) |
| | ENSPCTP00005025016 | LOW QUALITY PROTEIN: nucleotide triphosphate diphosphatase NUDT15-like. (132 aa) |
| | AK5 | Adenylate kinase isoenzyme 5; Belongs to the adenylate kinase family. (561 aa) |
| | ENTPD8 | Ectonucleoside triphosphate diphosphohydrolase 8 isoform X1; Belongs to the GDA1/CD39 NTPase family. (494 aa) |
| | NUDT13 | LOW QUALITY PROTEIN: nucleoside diphosphate-linked moiety X motif 13. (351 aa) |
| | UCKL1 | Uridine-cytidine kinase; Belongs to the uridine kinase family. (549 aa) |
| | CDADC1 | Cytidine and dCMP deaminase domain-containing protein 1 isoform X1. (515 aa) |
| | NUDT5 | ADP-sugar pyrophosphatase isoform X3; Belongs to the Nudix hydrolase family. (219 aa) |
| | ENSPCTP00005005081 | annotation not available (385 aa) |
| | NT5C3A | 5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (331 aa) |
| | IQCJ | IQ domain-containing protein J. (110 aa) |
| | NME8 | Thioredoxin domain-containing protein 3. (429 aa) |
| | LOC102980579 | Schwannomin-interacting protein 1 isoform X1. (551 aa) |
| | PAICS | Multifunctional protein ADE2 isoform X2. (425 aa) |
| | PPAT | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (540 aa) |
| | RRM2B | Ribonucleoside-diphosphate reductase subunit M2 B. (351 aa) |
| | DCTD | Deoxycytidylate deaminase. (178 aa) |
| | NT5M | 5'(3')-deoxyribonucleotidase, mitochondrial. (228 aa) |
| | CTPS2 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (586 aa) |
| | PAPOLG | poly(A) polymerase gamma isoform X1. (813 aa) |
| | AK8 | Adenylate kinase 8 isoform X1; Belongs to the adenylate kinase family. (479 aa) |
| | SAMHD1 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X3. (628 aa) |
| | UMPS | Uridine 5'-monophosphate synthase. (480 aa) |
| | CAD | CAD protein isoform X2. (2225 aa) |
| | APRT | Adenine phosphoribosyltransferase isoform X2. (180 aa) |
| | ADSS1 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa) |
| | LOC102979298 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (328 aa) |
| | NT5C | 5'(3')-deoxyribonucleotidase, cytosolic type isoform X1. (214 aa) |
| | DGUOK | Deoxyguanosine kinase, mitochondrial isoform X2. (280 aa) |
| | SETBP1 | SET-binding protein isoform X2. (1598 aa) |
| | UCK1 | Uridine-cytidine kinase; Belongs to the uridine kinase family. (277 aa) |
| | UPP2 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (318 aa) |
| | AK1 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (211 aa) |
| | ENSPCTP00005011914 | annotation not available (109 aa) |
| | ENTPD6 | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (483 aa) |
| | GLRX | Glutaredoxin-1 isoform X1. (106 aa) |
| | LOC102976077 | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like. (165 aa) |
| | ENSPCTP00005012780 | annotation not available (218 aa) |
| | TK2 | Thymidine kinase 2, mitochondrial. (120 aa) |
| | XDH | Xanthine dehydrogenase/oxidase. (219 aa) |
| | NUDT6 | Nucleoside diphosphate-linked moiety X motif 6 isoform X1; Belongs to the Nudix hydrolase family. (316 aa) |
| | ATIC | Bifunctional purine biosynthesis protein PURH. (592 aa) |
| | ADSL | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (514 aa) |
| | NME3 | Nucleoside diphosphate kinase. (169 aa) |
| | CMPK2 | UMP-CMP kinase 2, mitochondrial. (447 aa) |
| | AK9 | Adenylate kinase 9. (724 aa) |
| | AK9-2 | Adenylate/nucleoside-diphosphate kinase. (294 aa) |
| | PUDP | Pseudouridine-5'-phosphatase isoform X6. (231 aa) |
| | LOC114484283 | Glutamine-rich protein 1. (455 aa) |
| | DCTPP1 | dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (169 aa) |
| | PFAS | Phosphoribosylformylglycinamidine synthase isoform X2. (1338 aa) |
| | RRM2 | Ribonucleoside-diphosphate reductase subunit M2 isoform X1. (408 aa) |
| | ENSPCTP00005018272 | annotation not available (153 aa) |
| | ADPRM | Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X7. (341 aa) |
| | LOC112063265 | Uridine phosphorylase 1-like. (169 aa) |
| | LOC112062924 | CTP synthase 1-B-like. (150 aa) |
| | MARVELD1 | MARVEL domain-containing protein 1. (173 aa) |
| | LOC112063121 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (838 aa) |
| | LOC102994250 | Trifunctional purine biosynthetic protein adenosine-3 isoform X1. (433 aa) |
| | NT5DC1 | 5'-nucleotidase domain-containing protein 1 isoform X1. (452 aa) |
| | CDA | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa) |
| | TXNDC8 | Thioredoxin; Belongs to the thioredoxin family. (127 aa) |
| | CMPK1 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (313 aa) |
| | LOC114485901 | Uracil phosphoribosyltransferase-like. (156 aa) |
| | TXN | Thioredoxin isoform X2. (105 aa) |
| | DTYMK | Thymidylate kinase isoform X3. (212 aa) |
| | LOC112063320 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (102 aa) |
| | ADA | Adenosine deaminase isoform X2. (352 aa) |
| | ENTPD4 | Ectonucleoside triphosphate diphosphohydrolase 4 isoform X1; Belongs to the GDA1/CD39 NTPase family. (616 aa) |
| | ENSPCTP00005021490 | annotation not available (102 aa) |
| | DUT | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X2. (167 aa) |
| | LOC112062733 | Uridine phosphorylase 1-like. (169 aa) |
| | ENTPD7 | Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (605 aa) |
| | ENTPD2 | LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (481 aa) |
| | NME2 | Nucleoside diphosphate kinase. (152 aa) |
| | NME1 | Nucleoside diphosphate kinase. (152 aa) |
| | NT5C1B | LOW QUALITY PROTEIN: cytosolic 5'-nucleotidase 1B. (539 aa) |
| | NRSN1 | Neurensin-1. (195 aa) |
| | IPO13 | Importin-13 isoform X1. (963 aa) |
| | NT5E | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. (574 aa) |
| | ENSPCTP00005023524 | annotation not available (222 aa) |
