STRINGSTRING
PLCG1 PLCG1 PIK3CB PIK3CB NCK1 NCK1 MYO1G MYO1G LOC114486352 LOC114486352 ENSPCTP00005000591 ENSPCTP00005000591 VAV3 VAV3 LOC102983864 LOC102983864 ACTR3 ACTR3 FCGR3A FCGR3A LOC112062432 LOC112062432 ENSPCTP00005001666 ENSPCTP00005001666 PLD5 PLD5 ELMO1 ELMO1 PLD1 PLD1 CYFIP2 CYFIP2 ENSPCTP00005003353 ENSPCTP00005003353 WASL WASL PIK3CA PIK3CA ENSPCTP00005003646 ENSPCTP00005003646 ARPC5 ARPC5 CYFIP1 CYFIP1 MYO5C MYO5C LOC102991986 LOC102991986 ABI1 ABI1 MYO5A MYO5A MYO10 MYO10 ABI2 ABI2 LOC102978676 LOC102978676 ENSPCTP00005005957 ENSPCTP00005005957 VAV2 VAV2 ENSPCTP00005006801 ENSPCTP00005006801 ENSPCTP00005007648 ENSPCTP00005007648 WIPF3 WIPF3 RAC1-2 RAC1-2 ENSPCTP00005007913 ENSPCTP00005007913 WIPF1 WIPF1 NF2 NF2 ENSPCTP00005009779 ENSPCTP00005009779 LOC102994593 LOC102994593 HSP90AB1 HSP90AB1 TRAV3 TRAV3 WAS WAS CRK CRK ENSPCTP00005009958 ENSPCTP00005009958 ENSPCTP00005010003 ENSPCTP00005010003 ENSPCTP00005010067 ENSPCTP00005010067 PLD4 PLD4 ENSPCTP00005010137 ENSPCTP00005010137 ENSPCTP00005010194 ENSPCTP00005010194 TRAV10 TRAV10 ENSPCTP00005010581 ENSPCTP00005010581 ENSPCTP00005010619 ENSPCTP00005010619 ENSPCTP00005010632 ENSPCTP00005010632 ENSPCTP00005010645 ENSPCTP00005010645 ENSPCTP00005010661 ENSPCTP00005010661 ENSPCTP00005010685 ENSPCTP00005010685 BRK1 BRK1 LOC102983835 LOC102983835 ACTR2 ACTR2 ENSPCTP00005011318 ENSPCTP00005011318 ENSPCTP00005011611 ENSPCTP00005011611 NCKAP1L NCKAP1L ARPC4 ARPC4 CFL2 CFL2 ACTR3B ACTR3B CDC42 CDC42 PAK1 PAK1 ABL1 ABL1 WASF2 WASF2 ENSPCTP00005013590 ENSPCTP00005013590 ENSPCTP00005013825 ENSPCTP00005013825 WIPF2 WIPF2 WASF1 WASF1 SYK SYK ELMO2 ELMO2 ENSPCTP00005015321 ENSPCTP00005015321 ENSPCTP00005016243 ENSPCTP00005016243 ENSPCTP00005016244 ENSPCTP00005016244 PRKCE PRKCE ENSPCTP00005016399 ENSPCTP00005016399 ENSPCTP00005016496 ENSPCTP00005016496 ENSPCTP00005016606 ENSPCTP00005016606 ENSPCTP00005016647 ENSPCTP00005016647 MYO1D MYO1D ARPC5L ARPC5L DOCK1 DOCK1 WASF3 WASF3 DSTN DSTN NCKAP1 NCKAP1 CD3G CD3G ARPC1A ARPC1A MYO1H MYO1H VAV1 VAV1 MAPK1 MAPK1 LOC114485415 LOC114485415 WASHC1 WASHC1 ENSPCTP00005020019 ENSPCTP00005020019 ENSPCTP00005020143 ENSPCTP00005020143 PLD3 PLD3 MAPK3 MAPK3 ELMO3 ELMO3 PIK3R1 PIK3R1 ARPC1B ARPC1B FMN2 FMN2 LOC112063002 LOC112063002 LIMK1 LIMK1 RAC1 RAC1 ENSPCTP00005023192 ENSPCTP00005023192 ACTL8 ACTL8 PLPP5 PLPP5 LOC102988905 LOC102988905 PTK2 PTK2 PLCG2 PLCG2 ENSPCTP00005024762 ENSPCTP00005024762 PLD2 PLD2 IGLL5 IGLL5 LOC102994479 LOC102994479 MYO1A MYO1A LOC102976708 LOC102976708 ENSPCTP00005026837 ENSPCTP00005026837 IGLV4-3 IGLV4-3 ENSPCTP00005027157 ENSPCTP00005027157 ENSPCTP00005027383 ENSPCTP00005027383 ENSPCTP00005027488 ENSPCTP00005027488 MYO1B MYO1B ENSPCTP00005027663 ENSPCTP00005027663 ENSPCTP00005027746 ENSPCTP00005027746 ENSPCTP00005027880 ENSPCTP00005027880 ENSPCTP00005028174 ENSPCTP00005028174 LOC114485526 LOC114485526 ARPC3 ARPC3 BAIAP2 BAIAP2 FMN1 FMN1 PIK3R2 PIK3R2 ACTG1 ACTG1 NCKIPSD NCKIPSD HSP90AA1 HSP90AA1 PLPP4 PLPP4 PRKCD PRKCD LOC114484905 LOC114484905 GRB2 GRB2 ENSPCTP00005032015 ENSPCTP00005032015
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1165 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
NCK1Cytoplasmic protein. (377 aa)
MYO1GUnconventional myosin-Ig; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1014 aa)
LOC114486352Unconventional myosin-Ig-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (278 aa)
ENSPCTP00005000591annotation not available (163 aa)
VAV3LOW QUALITY PROTEIN: guanine nucleotide exchange factor VAV3. (875 aa)
LOC102983864Low affinity immunoglobulin gamma Fc region receptor II. (317 aa)
ACTR3Actin-related protein 3 isoform X1; Belongs to the actin family. (418 aa)
FCGR3ALow affinity immunoglobulin gamma Fc region receptor III-A isoform X1. (257 aa)
LOC112062432Low affinity immunoglobulin gamma Fc region receptor III-like isoform X2. (275 aa)
ENSPCTP00005001666annotation not available (139 aa)
PLD5Inactive phospholipase D5. (535 aa)
ELMO1Engulfment and cell motility protein 1 isoform X2. (727 aa)
PLD1Phospholipase. (1180 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
ENSPCTP00005003353annotation not available (377 aa)
WASLNeural Wiskott-Aldrich syndrome protein isoform X2. (505 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSPCTP00005003646annotation not available (406 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
CYFIP1LOW QUALITY PROTEIN: cytoplasmic FMR1-interacting protein 1. (1253 aa)
MYO5CUnconventional myosin-Vc; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1742 aa)
LOC102991986Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
ABI1Abl interactor 1 isoform X9. (508 aa)
MYO5AUnconventional myosin-Va isoform X5; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1924 aa)
MYO10Unconventional myosin-X isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1958 aa)
ABI2Abl interactor 2 isoform X9. (510 aa)
LOC102978676TCR gamma alternate reading frame protein. (165 aa)
ENSPCTP00005005957annotation not available (127 aa)
VAV2Guanine nucleotide exchange factor VAV2. (864 aa)
ENSPCTP00005006801annotation not available (87 aa)
ENSPCTP00005007648annotation not available (204 aa)
WIPF3WAS/WASL-interacting protein family member 3 isoform X4. (462 aa)
RAC1-2Ras-related C3 botulinum toxin substrate 1. (185 aa)
ENSPCTP00005007913annotation not available (197 aa)
WIPF1WAS/WASL-interacting protein family member 1. (495 aa)
NF2Merlin. (541 aa)
ENSPCTP00005009779annotation not available (235 aa)
LOC102994593Immunoglobulin kappa light chain-like. (140 aa)
HSP90AB1Heat shock protein HSP 90-beta. (728 aa)
TRAV3T cell receptor alpha variable 3 (gene/pseudogene). (124 aa)
WASwiskott-Aldrich syndrome protein. (502 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
ENSPCTP00005009958annotation not available (151 aa)
ENSPCTP00005010003annotation not available (167 aa)
ENSPCTP00005010067annotation not available (103 aa)
PLD4Phospholipase D4 isoform X1. (432 aa)
ENSPCTP00005010137annotation not available (76 aa)
ENSPCTP00005010194annotation not available (135 aa)
TRAV10T cell receptor alpha variable 10. (135 aa)
ENSPCTP00005010581annotation not available (136 aa)
ENSPCTP00005010619annotation not available (143 aa)
ENSPCTP00005010632annotation not available (124 aa)
ENSPCTP00005010645annotation not available (136 aa)
ENSPCTP00005010661annotation not available (269 aa)
ENSPCTP00005010685annotation not available (148 aa)
BRK1Protein BRICK1 isoform X2. (75 aa)
LOC10298383585/88 kDa calcium-independent phospholipase A2 isoform X1. (778 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
ENSPCTP00005011318annotation not available (149 aa)
ENSPCTP00005011611annotation not available (160 aa)
NCKAP1LNck-associated protein 1-like. (1128 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
CFL2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
ACTR3BActin-related protein 3B isoform X3; Belongs to the actin family. (418 aa)
CDC42Cell division control protein 42 homolog isoform X1. (191 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
WASF2wiskott-Aldrich syndrome protein family member 2. (498 aa)
ENSPCTP00005013590annotation not available (707 aa)
ENSPCTP00005013825annotation not available (148 aa)
WIPF2WAS/WASL-interacting protein family member 2. (440 aa)
WASF1wiskott-Aldrich syndrome protein family member 1 isoform X3. (559 aa)
SYKTyrosine-protein kinase. (627 aa)
ELMO2Engulfment and cell motility protein 2 isoform X1. (720 aa)
ENSPCTP00005015321LOW QUALITY PROTEIN: heat shock protein HSP 90-alpha-like. (119 aa)
ENSPCTP00005016243annotation not available (581 aa)
ENSPCTP00005016244annotation not available (114 aa)
PRKCENon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (219 aa)
ENSPCTP00005016399annotation not available (160 aa)
ENSPCTP00005016496annotation not available (191 aa)
ENSPCTP00005016606annotation not available (151 aa)
ENSPCTP00005016647annotation not available (224 aa)
MYO1DUnconventional myosin-Id isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
DOCK1Dedicator of cytokinesis protein 1 isoform X1; Belongs to the DOCK family. (1331 aa)
WASF3wiskott-Aldrich syndrome protein family member 3 isoform X1. (501 aa)
DSTNDestrin; Belongs to the actin-binding proteins ADF family. (165 aa)
NCKAP1Nck-associated protein 1. (1156 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain. (178 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (367 aa)
MYO1HUnconventional myosin-Ih; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1038 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
LOC114485415Protein kinase C epsilon type-like. (172 aa)
WASHC1WASH complex subunit 1 isoform X3. (492 aa)
ENSPCTP00005020019annotation not available (211 aa)
ENSPCTP00005020143annotation not available (74 aa)
PLD3Phospholipase D3. (490 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
ELMO3Engulfment and cell motility protein 3 isoform X1. (720 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
FMN2Formin-2. (198 aa)
LOC112063002Heat shock protein 90-like. (498 aa)
LIMK1LIM domain kinase 1. (628 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (211 aa)
ENSPCTP00005023192annotation not available (146 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (365 aa)
PLPP5LOW QUALITY PROTEIN: phospholipid phosphatase 5. (258 aa)
LOC102988905Actin, cytoplasmic 1. (375 aa)
PTK2Focal adhesion kinase 1 isoform X10; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
ENSPCTP00005024762annotation not available (294 aa)
PLD2Phospholipase. (929 aa)
IGLL5Immunoglobulin lambda-like polypeptide 5. (139 aa)
LOC102994479Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (146 aa)
MYO1AUnconventional myosin-Ia; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
LOC102976708Immunoglobulin lambda-1 light chain-like. (240 aa)
ENSPCTP00005026837annotation not available (463 aa)
IGLV4-3Immunoglobulin lambda variable 4-3. (138 aa)
ENSPCTP00005027157annotation not available (160 aa)
ENSPCTP00005027383annotation not available (142 aa)
ENSPCTP00005027488annotation not available (146 aa)
MYO1BUnconventional myosin-Ib isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1136 aa)
ENSPCTP00005027663annotation not available (271 aa)
ENSPCTP00005027746annotation not available (128 aa)
ENSPCTP00005027880annotation not available (126 aa)
ENSPCTP00005028174annotation not available (144 aa)
LOC114485526Dedicator of cytokinesis protein 1-like; Belongs to the DOCK family. (210 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
BAIAP2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1. (350 aa)
FMN1LOW QUALITY PROTEIN: formin-1. (1184 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
NCKIPSDNCK-interacting protein with SH3 domain isoform X1. (721 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (733 aa)
PLPP4Phospholipid phosphatase 4 isoform X1. (271 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
LOC11448490585/88 kDa calcium-independent phospholipase A2-like. (156 aa)
GRB2Growth factor receptor-bound protein 2. (136 aa)
ENSPCTP00005032015annotation not available (235 aa)
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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