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| | LOC114487532 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B-like; Belongs to the cyclic nucleotide phosphodiesterase family. (357 aa) |
| | LOC114484769 | Adenylate kinase 4-like; Belongs to the adenylate kinase family. (143 aa) |
| | LOC112062886 | Nucleoside diphosphate kinase. (154 aa) |
| | NUDT16 | U8 snoRNA-decapping enzyme. (195 aa) |
| | AK2 | Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (241 aa) |
| | GUCY1A1 | Guanylate cyclase soluble subunit alpha-1 isoform X2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (699 aa) |
| | GUCY1B1 | Guanylate cyclase soluble subunit beta-1 isoform X3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (655 aa) |
| | PDE6A | Phosphodiesterase. (861 aa) |
| | ADCY1 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa) |
| | AK6 | Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa) |
| | ADSS | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa) |
| | HDDC3 | guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase MESH1. (179 aa) |
| | AMPD1 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (779 aa) |
| | PAPSS1 | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 isoform X1. (624 aa) |
| | PGM1-2 | Phosphoglucomutase-1 isoform X2; Belongs to the phosphohexose mutase family. (287 aa) |
| | NT5C1A | Cytosolic 5'-nucleotidase 1A. (365 aa) |
| | GUK1 | Guanylate kinase isoform X4. (198 aa) |
| | IMPDH1 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (571 aa) |
| | GDA | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (472 aa) |
| | NUDT9 | ADP-ribose pyrophosphatase, mitochondrial isoform X1. (350 aa) |
| | PNP | Purine nucleoside phosphorylase. (96 aa) |
| | PDE10A | Phosphodiesterase. (790 aa) |
| | DCK | Deoxycytidine kinase isoform X1. (376 aa) |
| | NUDT2 | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Belongs to the Nudix hydrolase family. (147 aa) |
| | LOC102975756 | Hypoxanthine-guanine phosphoribosyltransferase-like. (227 aa) |
| | GMPS | GMP synthase [glutamine-hydrolyzing]. (693 aa) |
| | ADCY10 | Adenylate cyclase type 10. (1614 aa) |
| | PDE7B | Phosphodiesterase. (500 aa) |
| | PDE8B | Phosphodiesterase. (841 aa) |
| | NME7 | Nucleoside diphosphate kinase 7; Belongs to the NDK family. (377 aa) |
| | NUDT5 | ADP-sugar pyrophosphatase isoform X3; Belongs to the Nudix hydrolase family. (219 aa) |
| | PDE11A | Phosphodiesterase. (933 aa) |
| | NT5C3A | 5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (331 aa) |
| | PDE1C | Phosphodiesterase. (769 aa) |
| | PPAT | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (540 aa) |
| | RRM2B | Ribonucleoside-diphosphate reductase subunit M2 B. (351 aa) |
| | NT5M | 5'(3')-deoxyribonucleotidase, mitochondrial. (228 aa) |
| | PDE7A | Phosphodiesterase. (483 aa) |
| | ENPP1 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (925 aa) |
| | AK8 | Adenylate kinase 8 isoform X1; Belongs to the adenylate kinase family. (479 aa) |
| | ENPP3 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. (874 aa) |
| | AK3 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (227 aa) |
| | GUCY1A2 | Guanylate cyclase soluble subunit alpha-2 isoform X2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (726 aa) |
| | APRT | Adenine phosphoribosyltransferase isoform X2. (180 aa) |
| | LOC102986245 | Phosphodiesterase. (627 aa) |
| | ADCY5 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1260 aa) |
| | ADSS1 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa) |
| | PDE5A | Phosphodiesterase. (865 aa) |
| | NT5C | 5'(3')-deoxyribonucleotidase, cytosolic type isoform X1. (214 aa) |
| | DGUOK | Deoxyguanosine kinase, mitochondrial isoform X2. (280 aa) |
| | ENPP4 | Bis(5'-adenosyl)-triphosphatase ENPP4 isoform X1. (456 aa) |
| | AK1 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (211 aa) |
| | ENTPD6 | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (483 aa) |
| | PRPS1 | Ribose-phosphate pyrophosphokinase 1. (318 aa) |
| | PDE6B | Phosphodiesterase. (854 aa) |
| | XDH | Xanthine dehydrogenase/oxidase. (219 aa) |
| | PDE4D | Phosphodiesterase. (807 aa) |
| | ADCY6 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa) |
| | GUCY2C | Guanylate cyclase. (1073 aa) |
| | ATIC | Bifunctional purine biosynthesis protein PURH. (592 aa) |
| | ADCY7 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa) |
| | ADSL | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (514 aa) |
| | NME3 | Nucleoside diphosphate kinase. (169 aa) |
| | PDE6H | Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma. (83 aa) |
| | PKM | Pyruvate kinase; Belongs to the pyruvate kinase family. (531 aa) |
| | AK9-2 | Adenylate/nucleoside-diphosphate kinase. (294 aa) |
| | PDE1A | Phosphodiesterase. (545 aa) |
| | NTPCR | Cancer-related nucleoside-triphosphatase isoform X2. (190 aa) |
| | PDE3B | Phosphodiesterase. (1117 aa) |
| | LOC102983042 | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (299 aa) |
| | PFAS | Phosphoribosylformylglycinamidine synthase isoform X2. (1338 aa) |
| | RRM2 | Ribonucleoside-diphosphate reductase subunit M2 isoform X1. (408 aa) |
| | ADPRM | Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X7. (341 aa) |
| | LOC112063121 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (838 aa) |
| | URAD | LOW QUALITY PROTEIN: putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. (167 aa) |
| | PDE3A | Phosphodiesterase. (1144 aa) |
| | GUCY2D | Guanylate cyclase. (1102 aa) |
| | PDE9A | Phosphodiesterase. (532 aa) |
| | PRPS2 | Ribose-phosphate pyrophosphokinase 2. (318 aa) |
| | ENTPD4 | Ectonucleoside triphosphate diphosphohydrolase 4 isoform X1; Belongs to the GDA1/CD39 NTPase family. (616 aa) |
| | ENTPD2 | LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (481 aa) |
| | NME2 | Nucleoside diphosphate kinase. (152 aa) |
| | NME1 | Nucleoside diphosphate kinase. (152 aa) |
| | NPR1 | Guanylate cyclase. (1058 aa) |
| | GUCY2F | Guanylate cyclase. (1108 aa) |
| | FHIT | Bis(5'-adenosyl)-triphosphatase. (149 aa) |
| | NT5E | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. (574 aa) |
| | ENTPD8 | Ectonucleoside triphosphate diphosphohydrolase 8 isoform X1; Belongs to the GDA1/CD39 NTPase family. (494 aa) |
| | PGM2 | Phosphoglucomutase-2 isoform X1. (616 aa) |
| | AK5 | Adenylate kinase isoenzyme 5; Belongs to the adenylate kinase family. (561 aa) |
| | AMPD2 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (799 aa) |
| | ENTPD3 | Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (529 aa) |
| | PDE6D | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...] (150 aa) |
| | PDE2A | Phosphodiesterase. (941 aa) |
| | LOC102992058 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa) |
| | LOC102985101 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa) |
| | NPR2 | Guanylate cyclase. (1047 aa) |
| | PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (573 aa) |
| | PAPSS2 | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 isoform X2. (621 aa) |
| | PDE1B | Phosphodiesterase. (516 aa) |
| | RRM1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (791 aa) |
| | ADK | Adenosine kinase isoform X5. (362 aa) |
| | NT5C2 | Cytosolic purine 5'-nucleotidase isoform X1. (573 aa) |
| | LOC102982435 | Exopolyphosphatase PRUNE1 isoform X1. (304 aa) |
| | NT5C3B | 5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (300 aa) |
| | AK7 | Adenylate kinase 7 isoform X1. (722 aa) |
| | ADCY8 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1247 aa) |
| | PDE6G | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma. (87 aa) |
| | PDE4C | Phosphodiesterase. (710 aa) |
| | PDE4B | Phosphodiesterase. (735 aa) |
| | GMPR2 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (340 aa) |
| | ADCY4 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa) |
| | ADCY9 | Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (577 aa) |
| | PDE6C | Phosphodiesterase. (860 aa) |
| | IMPDH2 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa) |
| | PDE8A | Phosphodiesterase. (831 aa) |
| | ENTPD5 | Ectonucleoside triphosphate diphosphohydrolase 5 isoform X1; Belongs to the GDA1/CD39 NTPase family. (428 aa) |
| | CANT1 | Soluble calcium-activated nucleotidase 1 isoform X1. (401 aa) |
| | ENTPD1 | Ectonucleoside triphosphate diphosphohydrolase 1 isoform X1; Belongs to the GDA1/CD39 NTPase family. (513 aa) |
| | NME4 | Nucleoside diphosphate kinase. (187 aa) |
| | AK4 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa) |
