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NMNAT3 NMNAT3 NMRK1 NMRK1 NT5C1A NT5C1A AOX1 AOX1 NADK NADK PNP PNP NMNAT2 NMNAT2 NAMPT NAMPT NMNAT1 NMNAT1 SIRT1 SIRT1 NT5M NT5M ENPP1 ENPP1 ENPP3 ENPP3 NT5C NT5C SIRT2 SIRT2 NAPRT NAPRT NADK2 NADK2 NADSYN1 NADSYN1 SIRT6 SIRT6 CD38 CD38 NT5E NT5E BST1 BST1 NMRK2 NMRK2 QPRT QPRT ASPDH ASPDH NUDT12 NUDT12 LOC102992890 LOC102992890 SIRT4 SIRT4 NNMT NNMT NNT NNT NT5C2 NT5C2 SIRT7 SIRT7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NMNAT3Nicotinamide-nucleotide adenylyltransferase. (244 aa)
NMRK1Nicotinamide riboside kinase 1. (199 aa)
NT5C1ACytosolic 5'-nucleotidase 1A. (365 aa)
AOX1Aldehyde oxidase. (1338 aa)
NADKNAD kinase. (451 aa)
PNPPurine nucleoside phosphorylase. (96 aa)
NMNAT2Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 isoform X1. (307 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (491 aa)
NMNAT1Nicotinamide-nucleotide adenylyltransferase. (281 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (731 aa)
NT5M5'(3')-deoxyribonucleotidase, mitochondrial. (228 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (925 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. (874 aa)
NT5C5'(3')-deoxyribonucleotidase, cytosolic type isoform X1. (214 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (426 aa)
NAPRTNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (538 aa)
NADK2NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. (442 aa)
NADSYN1Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (706 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6 isoform X1. (359 aa)
CD38ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1. (291 aa)
NT5E5'-nucleotidase; Belongs to the 5'-nucleotidase family. (574 aa)
BST1ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 isoform X1. (320 aa)
NMRK2Nicotinamide riboside kinase 2 isoform X6. (224 aa)
QPRTNicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (298 aa)
ASPDHPutative L-aspartate dehydrogenase isoform X2. (284 aa)
NUDT12Peroxisomal NADH pyrophosphatase NUDT12. (461 aa)
LOC102992890NAD-dependent protein deacetylase sirtuin-3. (172 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
NNMTNicotinamide N-methyltransferase. (264 aa)
NNTNAD(P) transhydrogenase, mitochondrial isoform X1. (1086 aa)
NT5C2Cytosolic purine 5'-nucleotidase isoform X1. (573 aa)
SIRT7NAD-dependent protein deacetylase sirtuin-7 isoform X1. (420 aa)
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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