STRINGSTRING
PIK3CB PIK3CB DGKB DGKB ITPKB ITPKB INPP4B INPP4B PIP4K2A PIP4K2A PIK3CA PIK3CA SYNJ1 SYNJ1 DGKI DGKI SYNJ2 SYNJ2 PIP5K1B PIP5K1B PLCD1 PLCD1 MTMR7 MTMR7 DGKH DGKH CALML5 CALML5 PIKFYVE PIKFYVE ITPKC ITPKC MTMR8 MTMR8 IPPK IPPK PIP4K2B PIP4K2B PLCB4 PLCB4 PRKCG PRKCG LOC102975028 LOC102975028 IMPAD1 IMPAD1 DGKA DGKA PIK3C3 PIK3C3 PRKCB PRKCB IMPA1 IMPA1 CDS2 CDS2 DGKQ DGKQ MTMR14 MTMR14 IMPA2 IMPA2 MTMR4 MTMR4 INPP4A INPP4A INPP5E INPP5E PLCB1 PLCB1 LOC102996886 LOC102996886 IPMK IPMK CDS1 CDS1 PI4K2B PI4K2B SACM1L SACM1L MTMR2 MTMR2 CDIPT CDIPT MTMR6 MTMR6 CALM3 CALM3 DGKE DGKE PIK3C2G PIK3C2G PLCZ1 PLCZ1 PLCG1 PLCG1 OCRL OCRL PI4K2A PI4K2A PLCD3 PLCD3 LOC102982193 LOC102982193 ITPR3 ITPR3 PLCB3 PLCB3 PIK3R1 PIK3R1 PIK3C2A PIK3C2A IP6K3 IP6K3 PLCG2 PLCG2 MTM1 MTM1 MTMR1 MTMR1 LOC114485603 LOC114485603 PI4KA PI4KA INPP5A INPP5A PIK3R3 PIK3R3 PPIP5K2 PPIP5K2 LOC102976604 LOC102976604 INPP1 INPP1 ITPKA ITPKA PI4KB PI4KB PIP5K1C PIP5K1C PIP5K1A PIP5K1A INPP5D INPP5D CALM2 CALM2 ITPR2 ITPR2 INPPL1 INPPL1 PTEN PTEN CALML4 CALML4 DGKD DGKD IP6K1 IP6K1 DGKZ DGKZ PIP4P1 PIP4P1 PIK3R2 PIK3R2 IP6K2 IP6K2 INPP5F INPP5F PLCE1 PLCE1 DGKK DGKK LOC102975509 LOC102975509
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
DGKBDiacylglycerol kinase. (803 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (940 aa)
INPP4BType II inositol 3,4-bisphosphate 4-phosphatase isoform X4. (939 aa)
PIP4K2APhosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1. (406 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SYNJ1Synaptojanin-1 isoform X6. (1603 aa)
DGKIDiacylglycerol kinase. (1079 aa)
SYNJ2Synaptojanin-2. (1243 aa)
PIP5K1BPhosphatidylinositol 4-phosphate 5-kinase type-1 beta. (540 aa)
PLCD1Phosphoinositide phospholipase C. (781 aa)
MTMR7Myotubularin-related protein 7 isoform X6. (660 aa)
DGKHDiacylglycerol kinase. (1162 aa)
CALML5Calmodulin-like. (153 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase isoform X1. (2110 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (685 aa)
MTMR8Myotubularin-related protein 8. (692 aa)
IPPKInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (547 aa)
PIP4K2BPhosphatidylinositol 5-phosphate 4-kinase type-2 beta isoform X1. (416 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
LOC102975028Kinase; Belongs to the inositol phosphokinase (IPK) family. (382 aa)
IMPAD1Inositol monophosphatase 3. (359 aa)
DGKADiacylglycerol kinase. (734 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
IMPA1Inositol-1-monophosphatase. (277 aa)
CDS2Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (445 aa)
DGKQDiacylglycerol kinase. (859 aa)
MTMR14Myotubularin-related protein 14 isoform X1. (648 aa)
IMPA2Inositol-1-monophosphatase. (288 aa)
MTMR4Myotubularin-related protein 4. (1122 aa)
INPP4AType I inositol 3,4-bisphosphate 4-phosphatase isoform X1. (973 aa)
INPP5E72 kDa inositol polyphosphate 5-phosphatase. (612 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC102996886Calmodulin-like; Belongs to the calmodulin family. (83 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (418 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (461 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2-beta isoform X1. (551 aa)
SACM1LPhosphatidylinositide phosphatase SAC1 isoform X3. (587 aa)
MTMR2Myotubularin-related protein 2 isoform X1. (643 aa)
CDIPTCDP-diacylglycerol--inositol 3-phosphatidyltransferase. (251 aa)
MTMR6Myotubularin-related protein 6. (621 aa)
CALM3Calmodulin-1; Belongs to the calmodulin family. (149 aa)
DGKEDiacylglycerol kinase. (564 aa)
PIK3C2GPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1; Belongs to the PI3/PI4-kinase family. (1483 aa)
PLCZ1Phosphoinositide phospholipase C. (640 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1165 aa)
OCRLInositol polyphosphate 5-phosphatase OCRL-1 isoform X1. (901 aa)
PI4K2APhosphatidylinositol 4-kinase type 2-alpha. (479 aa)
PLCD3Phosphoinositide phospholipase C. (784 aa)
LOC102982193Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma. (233 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
PIK3C2APhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha; Belongs to the PI3/PI4-kinase family. (1689 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (389 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
MTM1Myotubularin isoform X4. (603 aa)
MTMR1Myotubularin-related protein 1 isoform X3. (676 aa)
LOC114485603Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like. (143 aa)
PI4KAPhosphatidylinositol 4-kinase alpha isoform X1; Belongs to the PI3/PI4-kinase family. (1305 aa)
INPP5AType I inositol 1,4,5-trisphosphate 5-phosphatase isoform X2. (513 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
PPIP5K2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1263 aa)
LOC102976604Myotubularin-related protein 3. (589 aa)
INPP1Inositol polyphosphate 1-phosphatase isoform X1. (402 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
PI4KBPhosphatidylinositol 4-kinase beta isoform X1. (431 aa)
PIP5K1CPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1. (672 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X3. (562 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1180 aa)
CALM2Calmodulin-2. (82 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1264 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
CALML4Calmodulin-like protein 4 isoform X1. (120 aa)
DGKDDiacylglycerol kinase. (1216 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (276 aa)
DGKZDiacylglycerol kinase. (1119 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (277 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (425 aa)
INPP5FPhosphatidylinositide phosphatase SAC2 isoform X2. (1135 aa)
PLCE1Phosphoinositide phospholipase C. (2286 aa)
DGKKDiacylglycerol kinase. (1234 aa)
LOC102975509CDP-diacylglycerol--inositol 3-phosphatidyltransferase-like; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (266 aa)
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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