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| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | PPP2R3A | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1. (1151 aa) |
| | GNAI1 | Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (354 aa) |
| | DEGS1 | Sphingolipid delta(4)-desaturase DES1. (323 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (973 aa) |
| | GNAQ | Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa) |
| | FCER1G | High affinity immunoglobulin epsilon receptor subunit gamma. (86 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | S1PR1 | Sphingosine 1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | SGMS2 | Phosphatidylcholine:ceramide cholinephosphotransferase 2. (365 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (467 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa) |
| | PLD1 | Phospholipase. (1180 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | FCER1A | High affinity immunoglobulin epsilon receptor subunit alpha. (258 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5 isoform X1. (1366 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa) |
| | OPRD1 | Delta-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (368 aa) |
| | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (487 aa) |
| | GNAI3 | Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa) |
| | RAC1-2 | Ras-related C3 botulinum toxin substrate 1. (185 aa) |
| | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X2. (589 aa) |
| | MS4A2 | High affinity immunoglobulin epsilon receptor subunit beta-like. (241 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa) |
| | NSMAF | Protein FAN isoform X6. (917 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | S1PR2 | Sphingosine 1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | ASAH1 | Acid ceramidase isoform X1; Belongs to the acid ceramidase family. (395 aa) |
| | RAC2 | Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa) |
| | SPTLC3 | Serine palmitoyltransferase 3. (548 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (425 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | GNAI2 | Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa) |
| | SGPP1 | Sphingosine-1-phosphate phosphatase 1 isoform X1. (445 aa) |
| | SGPP2 | Sphingosine-1-phosphate phosphatase 2 isoform X2. (399 aa) |
| | GNA13 | Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (377 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | PPP2R3C | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1. (453 aa) |
| | BCL2 | Apoptosis regulator Bcl-2 isoform X1. (230 aa) |
| | ADORA3 | Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (123 aa) |
| | S1PR3 | Sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | RHOA | Ras homolog gene family, member A. (287 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | KNG1 | Kininogen-1 isoform X1. (627 aa) |
| | GAB2 | GRB2-associated-binding protein 2 isoform X1. (678 aa) |
| | CERS3 | Ceramide synthase 3. (431 aa) |
| | SPTLC1 | Serine palmitoyltransferase 1 isoform X1. (473 aa) |
| | CTSD | Cathepsin D; Belongs to the peptidase A1 family. (411 aa) |
| | SMPD2 | Sphingomyelin phosphodiesterase 2. (423 aa) |
| | PRKCE | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (219 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | CERS4 | Ceramide synthase 4. (393 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A isoform X1. (442 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (678 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa) |
| | LOC114485787 | Uncharacterized protein LOC114485787; Belongs to the peptidase A1 family. (436 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1200 aa) |
| | ROCK2 | Rho-associated protein kinase 2 isoform X5; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1387 aa) |
| | LOC114485885 | Uncharacterized protein LOC114485885; Belongs to the peptidase A1 family. (221 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (453 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa) |
| | S1PR5 | Sphingosine 1-phosphate receptor 5. (398 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | SGPL1 | Sphingosine-1-phosphate lyase 1. (559 aa) |
| | ACER1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa) |
| | SPHK1 | Sphingosine kinase 1. (391 aa) |
| | S1PR4 | Sphingosine 1-phosphate receptor 4. (385 aa) |
| | SPHK2 | Sphingosine kinase 2 isoform X1. (655 aa) |
| | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | PLD2 | Phospholipase. (929 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (623 aa) |
| | HRAS | GTPase HRas isoform X2. (189 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa) |
| | RELA | Transcription factor p65 isoform X3. (551 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | ASAH2 | Neutral ceramidase. (760 aa) |
| | SGMS1 | Phosphatidylcholine:ceramide cholinephosphotransferase 1. (419 aa) |
| | PDPK1 | 3-phosphoinositide-dependent protein kinase 1 isoform X1. (565 aa) |
| | CERS1 | Ceramide synthase 1. (350 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa) |
| | LOC102995842 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (210 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | BDKRB2 | B2 bradykinin receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (399 aa) |
| | CERS2 | Ceramide synthase 2. (380 aa) |
| | GNA12 | Guanine nucleotide-binding protein subunit alpha-12. (382 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa) |
| | RAC3 | Ras-related C3 botulinum toxin substrate 3 isoform X1. (192 aa) |
| | DEGS2 | Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform X2. (323 aa) |
| | ABCC1 | Multidrug resistance-associated protein 1 isoform X4. (1530 aa) |
| | PPP2R1B | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (668 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 isoform X2; Belongs to the protein kinase superfamily. (400 aa) |
| | SPTLC2 | Serine palmitoyltransferase 2 isoform X1. (561 aa) |
