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| | LOC112062897 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (476 aa) |
| | LOC112062939 | 14-3-3 protein homolog; Belongs to the 14-3-3 family. (193 aa) |
| | ATR | Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | TFDP2 | Transcription factor. (446 aa) |
| | STAG1 | Cohesin subunit SA-1 isoform X1. (1258 aa) |
| | ANAPC13 | Anaphase-promoting complex subunit 13 isoform X2. (74 aa) |
| | ENSPCTP00005000285 | LOW QUALITY PROTEIN: cullin-1-like. (471 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | CCNB1 | G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (433 aa) |
| | CDK7 | Cyclin-dependent kinase 7 isoform X1; Belongs to the protein kinase superfamily. (354 aa) |
| | ZBTB17 | Zinc finger and BTB domain-containing protein 17 isoform X3. (795 aa) |
| | SMC1B | Structural maintenance of chromosomes protein. (1236 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | CDC14A | Dual specificity protein phosphatase CDC14A isoform X10. (621 aa) |
| | WEE2 | Wee1-like protein kinase. (570 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | ORC2 | Origin recognition complex subunit 2 isoform X2. (578 aa) |
| | TTK | Dual specificity protein kinase TTK isoform X1. (901 aa) |
| | MAD2L2 | Mitotic spindle assembly checkpoint protein MAD2B. (176 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | PTTG1 | Securin isoform X1. (202 aa) |
| | DBF4 | Protein DBF4 homolog A isoform X2. (679 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa) |
| | CDC7 | Cell division cycle 7-related protein kinase isoform X1. (574 aa) |
| | YWHAH | 14-3-3 protein gamma/eta. (176 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (808 aa) |
| | TFDP1 | Transcription factor Dp-1 isoform X2. (457 aa) |
| | BUB3 | Mitotic checkpoint protein BUB3 isoform X2. (333 aa) |
| | CDC16 | Cell division cycle protein 16 homolog isoform X5. (620 aa) |
| | CCND3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (358 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3057 aa) |
| | RBL1 | Retinoblastoma-like protein 1 isoform X4. (1068 aa) |
| | CDC14B | Dual specificity protein phosphatase CDC14B isoform X5. (498 aa) |
| | CCNH | cyclin-H isoform X5; Belongs to the cyclin family. (328 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | CCNE2 | G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (405 aa) |
| | YWHAE | 14-3-3 protein epsilon isoform X1; Belongs to the 14-3-3 family. (255 aa) |
| | CHEK2 | Serine/threonine-protein kinase Chk2. (544 aa) |
| | MAD2L1 | Mitotic spindle assembly checkpoint protein MAD2A. (205 aa) |
| | ANAPC2 | Anaphase-promoting complex subunit 2; Belongs to the cullin family. (820 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (604 aa) |
| | CCNA2 | cyclin-A2; Belongs to the cyclin family. (432 aa) |
| | WEE1 | Wee1-like protein kinase. (646 aa) |
| | CDC25B | M-phase inducer phosphatase 2 isoform X1. (574 aa) |
| | ANAPC1 | Anaphase-promoting complex subunit 1 isoform X1. (1944 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | CCNB2 | G2/mitotic-specific cyclin-B2 isoform X1; Belongs to the cyclin family. (398 aa) |
| | ABL1 | Tyrosine-protein kinase. (1148 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (862 aa) |
| | LOC102982702 | S-phase kinase-associated protein 1-like; Belongs to the SKP1 family. (163 aa) |
| | BUB1 | Mitotic checkpoint serine/threonine-protein kinase BUB1 isoform X1. (1123 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | YWHAG | 14-3-3 protein gamma isoform X1; Belongs to the 14-3-3 family. (247 aa) |
| | SKP1 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | CDC26 | Anaphase-promoting complex subunit CDC26 isoform X2. (85 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa) |
| | ESPL1 | Separin. (1572 aa) |
| | RBX1 | E3 ubiquitin-protein ligase RBX1 isoform X1. (108 aa) |
| | CCND2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa) |
| | EP300 | Histone acetyltransferase p300 isoform X2. (2353 aa) |
| | RBL2 | Retinoblastoma-like protein 2. (1141 aa) |
| | ENSPCTP00005017127 | LOW QUALITY PROTEIN: 14-3-3 protein zeta/delta-like. (119 aa) |
| | CDKN2C | Cyclin-dependent kinase 4 inhibitor C. (168 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | YWHAQ | 14-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa) |
| | ORC3 | Origin recognition complex subunit 3 isoform X3. (779 aa) |
| | LOC102991021 | S-phase kinase-associated protein 2 isoform X1. (94 aa) |
| | RAD21 | Double-strand-break repair protein rad21 homolog. (630 aa) |
| | SMC1A | Structural maintenance of chromosomes protein. (1233 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (553 aa) |
| | SMC3 | Structural maintenance of chromosomes protein. (1217 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa) |
| | YWHAB | LOW QUALITY PROTEIN: 14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (245 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa) |
| | HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa) |
| | LOC112062958 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (228 aa) |
| | E2F4 | Transcription factor E2F4. (405 aa) |
| | CDKN2D | Cyclin-dependent kinase 4 inhibitor D. (166 aa) |
| | HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (422 aa) |
| | CDC23 | Cell division cycle protein 23 homolog. (597 aa) |
| | CDC25C | M-phase inducer phosphatase 3 isoform X1. (500 aa) |
| | TGFB3 | Transforming growth factor beta-3 proprotein. (456 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | LOC112067463 | Cyclin-dependent kinase inhibitor 1C-like. (269 aa) |
| | CDC25A | M-phase inducer phosphatase 1 isoform X1. (524 aa) |
| | CDKN2A | Cyclin-dependent kinase inhibitor 2A-like isoform X1. (156 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (560 aa) |
| | CDKN2B | Cyclin-dependent kinase 4 inhibitor B isoform X1. (138 aa) |
| | SFN | 14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | PRKDC | DNA-dependent protein kinase catalytic subunit isoform X1; Belongs to the PI3/PI4-kinase family. (4147 aa) |
| | E2F3 | Transcription factor E2F3 isoform X1. (467 aa) |
| | LOC114485751 | Dual specificity protein phosphatase CDC14A-like. (350 aa) |
| | CDC27 | Cell division cycle protein 27 homolog isoform X6. (831 aa) |
| | ENSPCTP00005024342 | LOW QUALITY PROTEIN: S-phase kinase-associated protein 1-like. (56 aa) |
| | CCNE1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa) |
| | RB1 | Retinoblastoma-associated protein isoform X2. (929 aa) |
| | CUL1 | Cullin-1 isoform X1; Belongs to the cullin family. (759 aa) |
| | E2F1 | Transcription factor E2F1 isoform X2. (437 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | FZR1 | Fizzy-related protein homolog isoform X2. (493 aa) |
| | CDC20 | Cell division cycle protein 20 homolog. (499 aa) |
| | ORC6 | Origin recognition complex subunit 6 isoform X1. (252 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) |
| | BUB1B | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta. (960 aa) |
| | CDK4 | Cyclin-dependent kinase 4 isoform X1; Belongs to the protein kinase superfamily. (303 aa) |
| | E2F2 | Transcription factor E2F2. (299 aa) |
| | ANAPC7 | LOW QUALITY PROTEIN: anaphase-promoting complex subunit 7. (565 aa) |
| | PKMYT1 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; Belongs to the protein kinase superfamily. (497 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (823 aa) |
| | CCNA1 | cyclin-A1; Belongs to the cyclin family. (421 aa) |
| | ANAPC5 | Anaphase-promoting complex subunit 5 isoform X1. (755 aa) |
| | CDK1 | Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (297 aa) |
| | MAD1L1 | Mitotic spindle assembly checkpoint protein MAD1. (717 aa) |
| | ANAPC11 | Anaphase-promoting complex subunit 11. (84 aa) |
| | CDC45 | Cell division control protein 45 homolog isoform X1. (567 aa) |
| | STAG2 | Cohesin subunit SA-2 isoform X1. (1268 aa) |
| | CREBBP | CREB-binding protein. (1362 aa) |
| | CCNB3 | G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (1511 aa) |
