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TRPC1 TRPC1 GNAI1 GNAI1 PPP3CA PPP3CA ADCY1 ADCY1 GNAQ GNAQ GRIA2 GRIA2 GRM1 GRM1 GRIA1 GRIA1 GRM6 GRM6 PLD1 PLD1 GNB1 GNB1 GRM8 GRM8 GNB4 GNB4 SHANK3 SHANK3 GNGT1 GNGT1 GNG11 GNG11 GNB5 GNB5 PLA2G4A PLA2G4A CACNA1C CACNA1C GRIK3 GRIK3 HOMER1 HOMER1 GRM3 GRM3 GNAI3 GNAI3 GNG13 GNG13 SLC1A1 SLC1A1 SLC1A6 SLC1A6 PLCB4 PLCB4 PRKCG PRKCG GRIA4 GRIA4 ADCY5 ADCY5 GRM5 GRM5 GRM2 GRM2 KCNJ3 KCNJ3 PRKCB PRKCB GRIN1 GRIN1 GNAI2 GNAI2 SLC38A3 SLC38A3 PPP3R1 PPP3R1 GRIN3A GRIN3A SLC17A6 SLC17A6 ADCY6 ADCY6 GRIN2B GRIN2B PLCB1 PLCB1 GRK2 GRK2 GRM7 GRM7 ADCY7 ADCY7 SLC17A8 SLC17A8 SLC1A2 SLC1A2 GNG5 GNG5 GNG10 GNG10 GLUL GLUL SLC38A2 SLC38A2 SLC38A1 SLC38A1 GNGT2 GNGT2 GNG4 GNG4 MAPK1 MAPK1 GNG12 GNG12 LOC112062965 LOC112062965 PPP3CC PPP3CC PRKACB PRKACB MAPK3 MAPK3 SLC1A3 SLC1A3 ITPR3 ITPR3 PLCB3 PLCB3 SHANK2 SHANK2 PLA2G4D PLA2G4D DLGAP1 DLGAP1 SLC17A7 SLC17A7 PLA2G4E PLA2G4E DLG4 DLG4 PRKACA PRKACA GNG3 GNG3 GRIK2 GRIK2 LOC102990390 LOC102990390 GNG8 GNG8 GRIN2C GRIN2C PLD2 PLD2 SHANK1 SHANK1 SLC1A7 SLC1A7 GNAS GNAS PPP3CB PPP3CB GNB3 GNB3 HOMER3 HOMER3 GLS GLS GNG7 GNG7 ITPR2 ITPR2 GLS2 GLS2 LOC102987258 LOC102987258 GNG2 GNG2 GRIK4 GRIK4 ADCY8 ADCY8 GRIA3 GRIA3 HOMER2 HOMER2 ADCY4 ADCY4 ADCY9 ADCY9 GNB2 GNB2 CACNA1A CACNA1A CACNA1D CACNA1D GRIN2D GRIN2D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRPC1Short transient receptor potential channel 1 isoform X4; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (354 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
GRIA2Glutamate receptor 2 isoform X1. (901 aa)
GRM1Metabotropic glutamate receptor 1 isoform X1. (1196 aa)
GRIA1Glutamate receptor 1 isoform X2. (918 aa)
GRM6Metabotropic glutamate receptor 6. (868 aa)
PLD1Phospholipase. (1180 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
GRM8Metabotropic glutamate receptor 8. (908 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
SHANK3SH3 and multiple ankyrin repeat domains protein 3. (1721 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (42 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X1. (395 aa)
PLA2G4APhospholipase A2. (781 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2187 aa)
GRIK3Glutamate receptor ionotropic, kainate 3. (919 aa)
HOMER1Homer protein homolog 1 isoform X2. (354 aa)
GRM3Metabotropic glutamate receptor 3 isoform X1. (879 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
SLC1A1Amino acid transporter. (524 aa)
SLC1A6Amino acid transporter. (564 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GRIA4Glutamate receptor 4 isoform X2. (902 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1260 aa)
GRM5Metabotropic glutamate receptor 5 isoform X1. (1204 aa)
GRM2Metabotropic glutamate receptor 2 isoform X1. (872 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1. (235 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (959 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
SLC38A3Sodium-coupled neutral amino acid transporter 3 isoform X2. (504 aa)
PPP3R1Calcineurin subunit B type 1. (188 aa)
GRIN3AGlutamate receptor ionotropic, NMDA 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1115 aa)
SLC17A6Vesicular glutamate transporter 2. (582 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1481 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
GRM7Metabotropic glutamate receptor 7 isoform X2. (922 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
SLC17A8Vesicular glutamate transporter 3 isoform X1. (589 aa)
SLC1A2Amino acid transporter. (579 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GLULGlutamine synthetase. (505 aa)
SLC38A2Sodium-coupled neutral amino acid transporter 2 isoform X1. (506 aa)
SLC38A1Sodium-coupled neutral amino acid transporter 1 isoform X1. (502 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC112062965cAMP-dependent protein kinase catalytic subunit beta-like. (470 aa)
PPP3CCSerine/threonine-protein phosphatase. (522 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily. (397 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
SLC1A3Amino acid transporter. (542 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
SHANK2SH3 and multiple ankyrin repeat domains protein 2. (1849 aa)
PLA2G4DPhospholipase A2. (817 aa)
DLGAP1Disks large-associated protein 1 isoform X1. (978 aa)
SLC17A7Vesicular glutamate transporter 1. (560 aa)
PLA2G4EPhospholipase A2. (868 aa)
DLG4Disks large homolog 4 isoform X2; Belongs to the MAGUK family. (696 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GRIK2Glutamate receptor ionotropic, kainate 2 isoform X1. (908 aa)
LOC102990390Phospholipase A2. (781 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GRIN2CGlutamate receptor ionotropic, NMDA 2C. (1221 aa)
PLD2Phospholipase. (929 aa)
SHANK1SH3 and multiple ankyrin repeat domains protein 1. (2156 aa)
SLC1A7Amino acid transporter. (504 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoform X1. (395 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
HOMER3Homer protein homolog 3. (360 aa)
GLSGlutaminase kidney isoform, mitochondrial isoform X1. (678 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
GLS2Glutaminase liver isoform, mitochondrial isoform X1. (602 aa)
LOC102987258Neuroendocrine secretory protein 55-like. (241 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (153 aa)
GRIK4Glutamate receptor ionotropic, kainate 4. (957 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1247 aa)
GRIA3Glutamate receptor 3 isoform X1. (894 aa)
HOMER2Homer protein homolog 2 isoform X2. (354 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (577 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2439 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
GRIN2DGlutamate receptor ionotropic, NMDA 2D. (1336 aa)
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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