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| | LOC112062897 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (476 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | MET | Hepatocyte growth factor receptor. (1412 aa) |
| | APC | Adenomatous polyposis coli protein isoform X1. (2875 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (973 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1208 aa) |
| | ZEB2 | Zinc finger E-box-binding homeobox 2 isoform X2. (1193 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | BMI1 | Polycomb complex protein BMI-1. (326 aa) |
| | FZD3 | Frizzled-3 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | HMGA2 | High mobility group protein HMGI-C. (109 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | PTGS2 | Prostaglandin G/H synthase 2. (604 aa) |
| | ZEB1 | Zinc finger E-box-binding homeobox 1 isoform X2. (1125 aa) |
| | EZR | Ezrin isoform X1. (586 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1049 aa) |
| | HNRNPK | Heterogeneous nuclear ribonucleoprotein K isoform X1. (464 aa) |
| | CCNG1 | cyclin-G1 isoform X1; Belongs to the cyclin family. (295 aa) |
| | ABCB1 | Multidrug resistance protein 1 isoform X1. (1278 aa) |
| | IGF2BP1 | Insulin-like growth factor 2 mRNA-binding protein 1. (577 aa) |
| | SIRT1 | NAD-dependent protein deacetylase sirtuin-1 isoform X1. (731 aa) |
| | ENSPCTP00005006491 | LOW QUALITY PROTEIN: induced myeloid leukemia cell differentiation protein Mcl-1 homolog. (186 aa) |
| | PDGFA | Platelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (158 aa) |
| | RDX | Radixin isoform X1. (604 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3057 aa) |
| | LOC102975528 | Caspase-3-like; Belongs to the peptidase C14A family. (277 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | NOTCH4 | Neurogenic locus notch homolog protein 4 isoform X1. (1989 aa) |
| | TIMP3 | Metalloproteinase inhibitor 3. (211 aa) |
| | HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa) |
| | CYP1B1 | Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (544 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa) |
| | NOTCH3 | Neurogenic locus notch homolog protein 3 isoform X2. (2320 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1610 aa) |
| | TNXB | LOW QUALITY PROTEIN: tenascin-X. (705 aa) |
| | SOS1 | Son of sevenless homolog 1 isoform X1. (1333 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (805 aa) |
| | CCNE2 | G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (405 aa) |
| | CRK | Adapter molecule crk isoform X1. (304 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1302 aa) |
| | HOXD10 | Homeobox protein Hox-D10. (340 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (466 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | CDC25B | M-phase inducer phosphatase 2 isoform X1. (574 aa) |
| | MCL1 | Induced myeloid leukemia cell differentiation protein Mcl-1. (351 aa) |
| | STMN1 | Stathmin; Belongs to the stathmin family. (149 aa) |
| | ABL1 | Tyrosine-protein kinase. (1148 aa) |
| | BCL2 | Apoptosis regulator Bcl-2 isoform X1. (230 aa) |
| | TRIM71 | E3 ubiquitin-protein ligase TRIM71. (870 aa) |
| | ST14 | Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (854 aa) |
| | BCL2L11 | Bcl-2-like protein 11 isoform X1. (196 aa) |
| | FOXP1 | Forkhead box protein P1 isoform X4. (696 aa) |
| | NOTCH1 | Neurogenic locus notch homolog protein 1. (2531 aa) |
| | SERPINB5 | Serpin B5; Belongs to the serpin family. (375 aa) |
| | STAT3 | Signal transducer and activator of transcription. (801 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (277 aa) |
| | MMP16 | Matrix metalloproteinase-16. (607 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (215 aa) |
| | RHOA | Ras homolog gene family, member A. (287 aa) |
| | ITGA5 | Integrin alpha-5; Belongs to the integrin alpha chain family. (1054 aa) |
| | TPM1 | Tropomyosin alpha-1 chain isoform X10; Belongs to the tropomyosin family. (421 aa) |
| | EFNA4 | ephrin-A4 isoform X1; Belongs to the ephrin family. (204 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1056 aa) |
| | CD44 | CD44 antigen isoform X1. (785 aa) |
| | SOS2 | Son of sevenless homolog 2. (1331 aa) |
| | PRKCE | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (219 aa) |
| | CCND2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa) |
| | EP300 | Histone acetyltransferase p300 isoform X2. (2353 aa) |
| | IRS1 | Insulin receptor substrate 1. (1245 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1701 aa) |
| | MMP9 | Matrix metalloproteinase-9. (709 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (800 aa) |
| | SHC1 | SHC-transforming protein 1 isoform X1. (584 aa) |
| | PDGFB | Platelet-derived growth factor subunit B isoform X2; Belongs to the PDGF/VEGF growth factor family. (240 aa) |
| | EFNA3 | ephrin-A3; Belongs to the ephrin family. (262 aa) |
| | DNMT3B | DNA (Cytosine-5)-methyltransferase 3B isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (855 aa) |
| | DDIT4 | DNA damage-inducible transcript 4 protein. (229 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1165 aa) |
| | VEGFA | Vascular endothelial growth factor A isoform X5; Belongs to the PDGF/VEGF growth factor family. (451 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa) |
| | CDCA5 | Sororin. (253 aa) |
| | TNR | tenascin-R. (1358 aa) |
| | SHC4 | SHC-transforming protein 4 isoform X2. (630 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer. (211 aa) |
| | SPRY2 | Protein sprouty homolog 2. (315 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa) |
| | PDCD4 | Programmed cell death protein 4 isoform X1. (469 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) |
| | HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa) |
| | MARCKS | Myristoylated alanine-rich C-kinase substrate. (334 aa) |
| | SLC7A1 | High affinity cationic amino acid transporter 1 isoform X1. (629 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | BCL2L2 | Bcl-2-like protein 2 isoform X2. (193 aa) |
| | HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (422 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (553 aa) |
| | CDC25C | M-phase inducer phosphatase 3 isoform X1. (500 aa) |
| | NOTCH2 | Neurogenic locus notch homolog protein 2. (2471 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (593 aa) |
| | CDC25A | M-phase inducer phosphatase 1 isoform X1. (524 aa) |
| | CDKN2A | Cyclin-dependent kinase inhibitor 2A-like isoform X1. (156 aa) |
| | SOX4 | Transcription factor SOX. (479 aa) |
| | E2F3 | Transcription factor E2F3 isoform X1. (467 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (776 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1112 aa) |
| | RASSF1 | Ras association domain-containing protein 1 isoform X2. (272 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (784 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | CCNE1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa) |
| | UBE2I | SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | EZH2 | Histone-lysine N-methyltransferase EZH2 isoform X7. (751 aa) |
| | ERBB3 | Receptor tyrosine-protein kinase erbB-3. (1338 aa) |
| | E2F1 | Transcription factor E2F1 isoform X2. (437 aa) |
| | HRAS | GTPase HRas isoform X2. (189 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (771 aa) |
| | EFNA2 | ephrin-A2; Belongs to the ephrin family. (214 aa) |
| | CRKL | Crk-like protein. (279 aa) |
| | IRS2 | Insulin receptor substrate 2 isoform X1. (1370 aa) |
| | RECK | Reversion-inducing cysteine-rich protein with Kazal motifs isoform X1. (971 aa) |
| | EFNA5 | ephrin-A5 isoform X1; Belongs to the ephrin family. (248 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | GLS | Glutaminase kidney isoform, mitochondrial isoform X1. (678 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1003 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | TNC | Tenascin isoform X1. (2201 aa) |
| | PLAU | Urokinase-type plasminogen activator isoform X1. (430 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) |
| | ZFPM2 | Zinc finger protein ZFPM2. (1151 aa) |
| | GLS2 | Glutaminase liver isoform, mitochondrial isoform X1. (602 aa) |
| | E2F2 | Transcription factor E2F2. (299 aa) |
| | BMF | Bcl-2-modifying factor. (204 aa) |
| | DICER1 | Endoribonuclease Dicer isoform X1; Belongs to the helicase family. Dicer subfamily. (1922 aa) |
| | PIM1 | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa) |
| | KIF23 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (967 aa) |
| | CYP24A1 | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (514 aa) |
| | APC2 | Adenomatous polyposis coli protein 2. (2257 aa) |
| | THBS1 | Thrombospondin-1. (1198 aa) |
| | RPTOR | Regulatory-associated protein of mTOR isoform X2. (1281 aa) |
| | DNMT3A | DNA (Cytosine-5)-methyltransferase 3A isoform X2; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (913 aa) |
| | EFNA1 | ephrin-A1 isoform X2; Belongs to the ephrin family. (142 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa) |
| | CREBBP | CREB-binding protein. (1362 aa) |
| | ABCC1 | Multidrug resistance-associated protein 1 isoform X4. (1530 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 isoform X2; Belongs to the protein kinase superfamily. (400 aa) |
| | GRB2 | Growth factor receptor-bound protein 2. (136 aa) |
