(90 nodes) Mixed, incl. Microbody membrane, and Claudin network (Loxodonta africana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PEX11A	Peroxisomal biogenesis factor 11 alpha. (271 aa)
	PEX13	Peroxisomal biogenesis factor 13. (375 aa)
	CLDN14	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (239 aa)
	ATAD1	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (361 aa)
	LMBRD1	LMBR1 domain containing 1. (539 aa)
	HTRA3	HtrA serine peptidase 3. (471 aa)
	TJP1	Tight junction protein 1; Belongs to the MAGUK family. (1750 aa)
	STOML1	Stomatin like 1. (397 aa)
	SLC27A5	Solute carrier family 27 member 5. (539 aa)
	AFDN	Afadin, adherens junction formation factor. (1501 aa)
	ABCD4	ATP binding cassette subfamily D member 4. (602 aa)
	ACOT8	Acyl-CoA thioesterase 8. (309 aa)
	PEX2	Peroxisomal biogenesis factor 2. (305 aa)
	ABCD2	ATP binding cassette subfamily D member 2. (742 aa)
	ABCD3	ATP binding cassette subfamily D member 3. (650 aa)
	PXMP2	Peroxisomal membrane protein 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (196 aa)
	SCP2	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (515 aa)
	GDAP1	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (358 aa)
	PXMP4	Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family. (212 aa)
	G3SV42_LOXAF	ACB domain-containing protein. (331 aa)
	DBI	Diazepam binding inhibitor, acyl-CoA binding protein. (103 aa)
	WFDC1	WAP four-disulfide core domain 1. (214 aa)
	JAM2	Junctional adhesion molecule 2. (261 aa)
	PEX5	Peroxisomal biogenesis factor 5. (641 aa)
	PEX10	Peroxisomal biogenesis factor 10. (318 aa)
	G3SZN8_LOXAF	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (208 aa)
	PEX7	Peroxisomal biogenesis factor 7. (322 aa)
	CLDN19	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
	CLDN1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	CLDN16	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
	PEX26	Peroxisomal biogenesis factor 26. (305 aa)
	ESAM	Endothelial cell adhesion molecule. (393 aa)
	TJP2	Uncharacterized protein; Belongs to the MAGUK family. (1151 aa)
	PLTP	Phospholipid transfer protein. (493 aa)
	BAAT	Bile acid-CoA:amino acid N-acyltransferase. (418 aa)
	STXBP6	Syntaxin binding protein 6. (210 aa)
	ATP10B	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1310 aa)
	CLDN5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
	CLDN11	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
	SLC25A17	Solute carrier family 25 member 17; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
	PEX12	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (359 aa)
	G3T8F1_LOXAF	Myosin_tail_1 domain-containing protein. (1201 aa)
	PEX3	Peroxisomal biogenesis factor 3. (373 aa)
	STXBP5	WD_REPEATS_REGION domain-containing protein. (716 aa)
	PEX6	Peroxisomal biogenesis factor 6. (978 aa)
	SDR39U1	Short chain dehydrogenase/reductase family 39U member 1. (294 aa)
	AGPS	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (671 aa)
	PEX5L	Peroxisomal biogenesis factor 5 like. (595 aa)
	GDAP1L1	Ganglioside induced differentiation associated protein 1 like 1. (370 aa)
	CLDN4	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
	CLDN6	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
	AMACR	Alpha-methylacyl-CoA racemase. (384 aa)
	HSDL2	Hydroxysteroid dehydrogenase like 2. (420 aa)
	CLDN15	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (241 aa)
	RAI1	Retinoic acid induced 1. (1821 aa)
	PEX1	Peroxisomal biogenesis factor 1. (1291 aa)
	JAM3	Junctional adhesion molecule 3. (311 aa)
	F11R	F11 receptor. (282 aa)
	ACBD5	Acyl-CoA binding domain containing 5. (389 aa)
	G3TTT1_LOXAF	Uncharacterized protein. (116 aa)
	G3TUG5_LOXAF	ACB domain-containing protein. (87 aa)
	GNPAT	Dihydroxyacetone phosphate acyltransferase. (655 aa)
	CLDN12	Claudin 12. (244 aa)
	CLDN9	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
	CLDN10	Claudin 10. (183 aa)
	G3U3R0_LOXAF	Uncharacterized protein. (272 aa)
	SLC25A33	Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
	OSTF1	Osteoclast stimulating factor 1. (216 aa)
	G3U4B3_LOXAF	Uncharacterized protein. (190 aa)
	PEX11G	Peroxisomal biogenesis factor 11 gamma. (240 aa)
	CLDN17	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
	CLDN8	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
	FAR1	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (515 aa)
	CBLN3	Cerebellin 3 precursor. (197 aa)
	PEX14	Peroxisomal biogenesis factor 14. (372 aa)
	PEX19	Uncharacterized protein. (300 aa)
	FAR2	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (515 aa)
	PEX16	Peroxisomal membrane protein PEX16. (339 aa)
	LOC100654296	Uncharacterized protein. (420 aa)
	CLDN2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
	ABCD1	ATP binding cassette subfamily D member 1. (739 aa)
	SLC25A36	Solute carrier family 25 member 36; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa)
	LOC100670825	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
	MPV17L	Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (196 aa)
	FAM185A	Family with sequence similarity 185 member A. (382 aa)
	CLDN3	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	TJP3	Tight junction protein 3; Belongs to the MAGUK family. (940 aa)
	CLDN23	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (291 aa)
	MPV17L2	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (200 aa)
	PEX11B	Peroxisomal biogenesis factor 11 beta. (259 aa)

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCD1	ABCD3	ENSLAFP00000027056	ENSLAFP00000003109	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 3.	0.724
ABCD1	ABCD4	ENSLAFP00000027056	ENSLAFP00000002397	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 4.	0.617
ABCD1	ACBD5	ENSLAFP00000027056	ENSLAFP00000018596	ATP binding cassette subfamily D member 1.	Acyl-CoA binding domain containing 5.	0.471
ABCD1	ATAD1	ENSLAFP00000027056	ENSLAFP00000001148	ATP binding cassette subfamily D member 1.	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	0.577
ABCD1	CLDN10	ENSLAFP00000027056	ENSLAFP00000021691	ATP binding cassette subfamily D member 1.	Claudin 10.	0.414
ABCD1	CLDN15	ENSLAFP00000027056	ENSLAFP00000014636	ATP binding cassette subfamily D member 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.449
ABCD1	FAM185A	ENSLAFP00000027056	ENSLAFP00000028613	ATP binding cassette subfamily D member 1.	Family with sequence similarity 185 member A.	0.564
ABCD1	G3SV42_LOXAF	ENSLAFP00000027056	ENSLAFP00000004083	ATP binding cassette subfamily D member 1.	ACB domain-containing protein.	0.471
ABCD1	GDAP1	ENSLAFP00000027056	ENSLAFP00000003664	ATP binding cassette subfamily D member 1.	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.	0.508
ABCD1	GDAP1L1	ENSLAFP00000027056	ENSLAFP00000013075	ATP binding cassette subfamily D member 1.	Ganglioside induced differentiation associated protein 1 like 1.	0.436
ABCD1	HSDL2	ENSLAFP00000027056	ENSLAFP00000014420	ATP binding cassette subfamily D member 1.	Hydroxysteroid dehydrogenase like 2.	0.412
ABCD1	LMBRD1	ENSLAFP00000027056	ENSLAFP00000001247	ATP binding cassette subfamily D member 1.	LMBR1 domain containing 1.	0.564
ABCD1	MPV17L2	ENSLAFP00000027056	ENSLAFP00000029385	ATP binding cassette subfamily D member 1.	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	0.421
ABCD1	PEX11A	ENSLAFP00000027056	ENSLAFP00000000465	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 11 alpha.	0.580
ABCD1	PEX11B	ENSLAFP00000027056	ENSLAFP00000029476	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 11 beta.	0.580
ABCD1	PEX11G	ENSLAFP00000027056	ENSLAFP00000022840	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 11 gamma.	0.538
ABCD1	PEX12	ENSLAFP00000027056	ENSLAFP00000009891	ATP binding cassette subfamily D member 1.	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.	0.642
ABCD1	PEX13	ENSLAFP00000027056	ENSLAFP00000000691	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 13.	0.718
ABCD1	PEX14	ENSLAFP00000027056	ENSLAFP00000024736	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 14.	0.652
ABCD1	PEX16	ENSLAFP00000027056	ENSLAFP00000025749	ATP binding cassette subfamily D member 1.	Peroxisomal membrane protein PEX16.	0.605

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