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| | LMTK2 | Lemur tyrosine kinase 2. (1441 aa) |
| | GFRAL | GDNF family receptor alpha like. (316 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1257 aa) |
| | NRTN | Neurturin. (197 aa) |
| | PIK3R2 | Uncharacterized protein. (724 aa) |
| | G3SMI1_LOXAF | Uncharacterized protein. (239 aa) |
| | INPPL1 | Inositol polyphosphate phosphatase like 1. (1265 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (795 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1038 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa) |
| | GAB1 | GRB2 associated binding protein 1. (694 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | FGF13 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa) |
| | NGFR | Nerve growth factor receptor. (414 aa) |
| | PSPN | TGF_BETA_2 domain-containing protein. (157 aa) |
| | PDGFD | Platelet derived growth factor D. (370 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1220 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1112 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (359 aa) |
| | PIR | Pirin; Belongs to the pirin family. (290 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | GFRA1 | GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (457 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (270 aa) |
| | G3SYI0_LOXAF | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (660 aa) |
| | ANGPT4 | Angiopoietin 4. (502 aa) |
| | GRAP2 | GRB2 related adaptor protein 2. (327 aa) |
| | ABL1 | Tyrosine-protein kinase. (1142 aa) |
| | CBL | Cbl proto-oncogene. (906 aa) |
| | NTRK2 | Tyrosine-protein kinase receptor. (820 aa) |
| | ANGPT1 | Angiopoietin 1. (498 aa) |
| | SH2B3 | SH2B adaptor protein 3. (568 aa) |
| | GFRA2 | GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. (464 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | EPGN | Epithelial mitogen. (153 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (96 aa) |
| | HBEGF | Heparin binding EGF like growth factor. (208 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | FLT4 | Fms related tyrosine kinase 4. (1271 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1330 aa) |
| | SH2D2A | SH2 domain containing 2A. (386 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa) |
| | HIVEP2 | Human immunodeficiency virus type I enhancer binding protein 2. (2446 aa) |
| | SHC1 | SHC adaptor protein 1. (583 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | EREG | Epiregulin. (163 aa) |
| | VAV2 | Vav guanine nucleotide exchange factor 2. (866 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1316 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1091 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | GRAP | Uncharacterized protein. (217 aa) |
| | BMX | Tyrosine-protein kinase. (655 aa) |
| | IGF2 | Insulin like growth factor 2. (175 aa) |
| | PIK3AP1 | Phosphoinositide-3-kinase adaptor protein 1. (844 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1381 aa) |
| | CD34 | CD34 molecule. (386 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (191 aa) |
| | KLB | Klotho beta. (1042 aa) |
| | SYK | Tyrosine-protein kinase. (629 aa) |
| | ANGPT2 | Angiopoietin 2. (495 aa) |
| | LCP2 | Lymphocyte cytosolic protein 2. (535 aa) |
| | FGFRL1 | Fibroblast growth factor receptor like 1. (478 aa) |
| | GDNF | Glial cell derived neurotrophic factor. (240 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | DOK6 | Docking protein 6. (331 aa) |
| | SHC3 | SHC adaptor protein 3. (463 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1168 aa) |
| | AREG | Amphiregulin. (249 aa) |
| | TXK | Tyrosine-protein kinase. (528 aa) |
| | TEC | Tyrosine-protein kinase. (631 aa) |
| | IGFBP3 | Insulin like growth factor binding protein 3. (296 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1206 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | CBLB | Cbl proto-oncogene B. (983 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (200 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1342 aa) |
| | GFRA3 | GDNF family receptor alpha 3. (372 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (508 aa) |
| | G3TEJ6_LOXAF | Uncharacterized protein. (646 aa) |
| | NTRK3 | Tyrosine-protein kinase receptor. (825 aa) |
| | BCR | BCR activator of RhoGEF and GTPase. (1250 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (801 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (996 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | G3TG57_LOXAF | IlGF domain-containing protein. (118 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (271 aa) |
| | INPP5D | Inositol polyphosphate-5-phosphatase D. (1191 aa) |
| | BTC | Betacellulin. (177 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (160 aa) |
| | SH2B1 | SH2B adaptor protein 1. (756 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (960 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa) |
| | NRG1 | Neuregulin 1. (700 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa) |
| | ARTN | Artemin. (209 aa) |
| | SORT1 | Sortilin. (729 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (878 aa) |
| | FRS3 | Fibroblast growth factor receptor substrate 3. (494 aa) |
| | IRS2 | Insulin receptor substrate 2. (1342 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (847 aa) |
| | BTK | Tyrosine-protein kinase. (661 aa) |
| | RET | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1112 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (831 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (845 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa) |
| | NRG4 | Neuregulin 4. (111 aa) |
| | TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1139 aa) |
| | G3TML4_LOXAF | Uncharacterized protein. (411 aa) |
| | DOK2 | Docking protein 2. (430 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa) |
| | TGFA | Transforming growth factor alpha. (129 aa) |
| | HGF | Uncharacterized protein; Belongs to the peptidase S1 family. (480 aa) |
| | G3TR48_LOXAF | TGF_BETA_2 domain-containing protein. (307 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (804 aa) |
| | SORCS2 | Sortilin. (357 aa) |
| | MPL | MPL proto-oncogene, thrombopoietin receptor. (633 aa) |
| | IL34 | Interleukin 34. (234 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa) |
| | IGFBP5 | Insulin like growth factor binding protein 5. (272 aa) |
| | VEGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (215 aa) |
| | G3TWY0_LOXAF | Uncharacterized protein. (88 aa) |
| | SPRY1 | Sprouty RTK signaling antagonist 1. (318 aa) |
| | TEK | TEK receptor tyrosine kinase. (1125 aa) |
| | NGF | Nerve growth factor; Belongs to the NGF-beta family. (242 aa) |
| | THPO | Thrombopoietin. (319 aa) |
| | ERBB4 | GF_recep_IV domain-containing protein. (135 aa) |
| | BLNK | B cell linker. (448 aa) |
| | DOK5 | Docking protein 5. (306 aa) |
| | INSRR | Insulin receptor related receptor. (1300 aa) |
| | G3U2E6_LOXAF | Ig-like domain-containing protein. (293 aa) |
| | PIK3R3 | Uncharacterized protein. (509 aa) |
| | G3U4I8_LOXAF | PH domain-containing protein. (316 aa) |
| | RAPGEF1 | Rap guanine nucleotide exchange factor 1. (1221 aa) |
| | IGFBP6 | Insulin like growth factor binding protein 6. (234 aa) |
| | NRG2 | Neuregulin 2. (625 aa) |
| | G3U868_LOXAF | Ig-like domain-containing protein. (168 aa) |
| | G3U8E8_LOXAF | TGF_BETA_2 domain-containing protein. (150 aa) |
| | SPRY3 | Sprouty RTK signaling antagonist 3. (222 aa) |
| | G3U9C7_LOXAF | Uncharacterized protein. (259 aa) |
| | G3UAF1_LOXAF | Uncharacterized protein. (221 aa) |
| | LMTK3 | Protein kinase domain-containing protein. (271 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa) |
| | FLT3LG | Fms related tyrosine kinase 3 ligand. (240 aa) |
| | IRS1 | Insulin receptor substrate 1. (1119 aa) |
| | IGFBP2 | Insulin like growth factor binding protein 2. (178 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1161 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (555 aa) |
| | LAT | Linker for activation of T cells. (246 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1366 aa) |
| | G3UEY2_LOXAF | Recep_L_domain domain-containing protein. (62 aa) |
| | NTF4 | Neurotrophin 4; Belongs to the NGF-beta family. (208 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (414 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (134 aa) |
| | PTPRJ | Protein tyrosine phosphatase receptor type J. (1053 aa) |
| | PDGFRL | Platelet derived growth factor receptor like. (373 aa) |
| | G3ULQ3_LOXAF | Tyrosine-protein phosphatase non-receptor type. (369 aa) |
| | FGF18 | Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (198 aa) |
| | G3UMU2_LOXAF | Uncharacterized protein. (43 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (840 aa) |
| | GAB2 | GRB2 associated binding protein 2. (672 aa) |
| | BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (255 aa) |
