STRINGSTRING
TNFRSF4 TNFRSF4 CD274 CD274 TNFRSF14 TNFRSF14 TNFSF4 TNFSF4 CD40LG CD40LG CTLA4 CTLA4 ICOS ICOS CD160 CD160 G3T1U1_LOXAF G3T1U1_LOXAF CD70 CD70 G3TBU1_LOXAF G3TBU1_LOXAF CD276 CD276 ICOSLG ICOSLG BTLA BTLA TNFRSF18 TNFRSF18 CD28 CD28 TNFSF8 TNFSF8 TNFSF14 TNFSF14 CD27 CD27 PDCD1 PDCD1 G3TSJ7_LOXAF G3TSJ7_LOXAF CD86 CD86 CD40 CD40 ACKR1 ACKR1 G3UII3_LOXAF G3UII3_LOXAF TNFRSF9 TNFRSF9 TNFSF9 TNFSF9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNFRSF4TNF receptor superfamily member 4. (265 aa)
CD274CD274 molecule. (290 aa)
TNFRSF14Uncharacterized protein. (232 aa)
TNFSF4TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (143 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)
ICOSInducible T cell costimulator. (198 aa)
CD160CD160 molecule. (187 aa)
G3T1U1_LOXAFTNFR-Cys domain-containing protein. (447 aa)
CD70TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (198 aa)
G3TBU1_LOXAFUncharacterized protein. (89 aa)
CD276CD276 molecule. (508 aa)
ICOSLGUncharacterized protein. (259 aa)
BTLAB and T lymphocyte associated. (275 aa)
TNFRSF18Uncharacterized protein. (226 aa)
CD28CD28 molecule. (203 aa)
TNFSF8Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family. (235 aa)
TNFSF14Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family. (241 aa)
CD27CD27 molecule. (261 aa)
PDCD1Programmed cell death 1. (283 aa)
G3TSJ7_LOXAFIG domain-containing protein. (280 aa)
CD86Ig-like domain-containing protein. (291 aa)
CD40CD40 molecule. (260 aa)
ACKR1Atypical chemokine receptor 1 (Duffy blood group). (331 aa)
G3UII3_LOXAFUncharacterized protein. (236 aa)
TNFRSF9TNF receptor superfamily member 9. (255 aa)
TNFSF9TNF superfamily member 9; Belongs to the tumor necrosis factor family. (244 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (22%) [HD]