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| | DVL3 | Dishevelled segment polarity protein 3. (715 aa) |
| | CTDNEP1 | CTD nuclear envelope phosphatase 1. (245 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | GRHL3 | Grainyhead like transcription factor 3. (603 aa) |
| | LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (907 aa) |
| | CSNK1A1 | Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (337 aa) |
| | DKK4 | Dickkopf WNT signaling pathway inhibitor 4. (222 aa) |
| | CSNK1G2 | Casein kinase 1 gamma 2. (417 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (493 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa) |
| | GATA3 | GATA binding protein 3. (443 aa) |
| | CDK14 | Cyclin dependent kinase 14; Belongs to the protein kinase superfamily. (469 aa) |
| | JUP | Junction plakoglobin. (741 aa) |
| | CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | RSPO3 | R-spondin 3. (212 aa) |
| | WDR61 | WD repeat domain 61. (305 aa) |
| | CUL3 | Cullin 3; Belongs to the cullin family. (746 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) |
| | KLHL12 | Kelch like family member 12. (568 aa) |
| | STK4 | Serine/threonine kinase 4. (511 aa) |
| | PKD2 | Polycystin 2, transient receptor potential cation channel. (973 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | NKD1 | NKD inhibitor of WNT signaling pathway 1. (470 aa) |
| | TNKS | Poly [ADP-ribose] polymerase. (1317 aa) |
| | CELSR3 | Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3307 aa) |
| | CPE | Carboxypeptidase E. (476 aa) |
| | STK3 | Serine/threonine kinase 3. (497 aa) |
| | VAX2 | Ventral anterior homeobox 2. (206 aa) |
| | CTHRC1 | Collagen triple helix repeat containing 1. (244 aa) |
| | FERMT2 | Fermitin family member 2. (680 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2096 aa) |
| | CSNK1D | Casein kinase 1 delta. (416 aa) |
| | RSPO1 | R-spondin 1. (263 aa) |
| | NDRG2 | NDRG family member 2. (371 aa) |
| | EDN1 | Endothelin 1. (202 aa) |
| | SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (359 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | UBAC2 | UBA domain containing 2. (345 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | CSNK1G3 | Casein kinase 1 gamma 3; Belongs to the protein kinase superfamily. (449 aa) |
| | NDP | Norrin cystine knot growth factor NDP. (133 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (96 aa) |
| | KREMEN1 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (446 aa) |
| | DKK1 | Dickkopf-like protein 1. (268 aa) |
| | RECK | Reversion inducing cysteine rich protein with kazal motifs. (961 aa) |
| | TMEM88 | Transmembrane protein 88. (153 aa) |
| | LATS2 | Large tumor suppressor kinase 2. (1070 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2581 aa) |
| | EPM2A | EPM2A glucan phosphatase, laforin. (325 aa) |
| | AMOTL2 | Angiomotin like 2. (779 aa) |
| | ROR2 | Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (911 aa) |
| | PYGO2 | Pygopus family PHD finger 2. (406 aa) |
| | LZTS2 | Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (675 aa) |
| | LMBR1L | Limb development membrane protein 1 like; Belongs to the LIMR family. (489 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa) |
| | TLE3 | TLE family member 3, transcriptional corepressor. (772 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1140 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | DRAXIN | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | PAF1 | PAF1 homolog, Paf1/RNA polymerase II complex component. (464 aa) |
| | TLE4 | TLE family member 4, transcriptional corepressor. (758 aa) |
| | WWOX | Uncharacterized protein. (172 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) |
| | ROR1 | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (908 aa) |
| | SCYL2 | SCY1 like pseudokinase 2. (929 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (443 aa) |
| | WIF1 | WNT inhibitory factor 1. (379 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (349 aa) |
| | APC | APC regulator of WNT signaling pathway. (2836 aa) |
| | SFRP5 | Secreted frizzled related protein 5. (315 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | LRP4 | LDL receptor related protein 4. (1905 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | GID8 | GID complex subunit 8 homolog. (229 aa) |
| | CYLD | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (774 aa) |
| | MESD | Mesoderm development LRP chaperone. (231 aa) |
| | DAB2 | DAB adaptor protein 2. (768 aa) |
| | BCL9 | BCL9 transcription coactivator. (1426 aa) |
| | ZRANB1 | Zinc finger RANBP2-type containing 1. (708 aa) |
| | CCDC90B | Uncharacterized protein. (254 aa) |
| | PKD1 | Polycystin 1, transient receptor potential channel interacting. (4255 aa) |
| | GSK3A | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (482 aa) |
| | CALCOCO1 | Calcium binding and coiled-coil domain 1. (691 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa) |
| | PYGO1 | Pygopus family PHD finger 1. (403 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (600 aa) |
| | USP34 | Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3532 aa) |
| | LEO1 | LEO1 homolog, Paf1/RNA polymerase II complex component. (667 aa) |
| | RYK | Receptor like tyrosine kinase. (535 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (399 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa) |
| | NXN | Nucleoredoxin. (315 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | TCF7 | Transcription factor 7. (476 aa) |
| | INVS | Inversin. (1059 aa) |
| | MYOC | Myocilin. (506 aa) |
| | CCDC88C | Coiled-coil domain containing 88C. (1944 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (334 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa) |
| | SIAH1 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (282 aa) |
| | RTF1 | RTF1 homolog, Paf1/RNA polymerase II complex component. (711 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) |
| | CTNNB1 | Catenin beta 1. (780 aa) |
| | CCAR2 | Cell cycle and apoptosis regulator 2. (922 aa) |
| | STRN | Striatin. (780 aa) |
| | CSNK1G1 | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (459 aa) |
| | RSPO2 | R-spondin 2. (242 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (387 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (737 aa) |
| | AMOTL1 | Angiomotin like 1. (939 aa) |
| | LDB1 | LIM domain binding 1. (411 aa) |
| | TAX1BP3 | Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. (124 aa) |
| | CTNNBIP1 | Catenin beta interacting protein 1. (152 aa) |
| | SDC1 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (305 aa) |
| | FRAT2 | FRAT regulator of WNT signaling pathway 2. (185 aa) |
| | TLE6 | Uncharacterized protein. (304 aa) |
| | WLS | Wnt ligand secretion mediator. (541 aa) |
| | SFRP4 | Secreted frizzled related protein 4. (348 aa) |
| | LOC100666300 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa) |
| | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (449 aa) |
| | WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa) |
| | GSC | Goosecoid homeobox. (256 aa) |
| | BARX1 | BARX homeobox 1. (180 aa) |
| | FRZB | Frizzled related protein. (325 aa) |
| | HMGXB4 | HMG-box containing 4. (592 aa) |
| | PLPP3 | acidPPc domain-containing protein. (312 aa) |
| | EDA | Ectodysplasin A; Belongs to the tumor necrosis factor family. (224 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa) |
| | HESX1 | HESX homeobox 1. (185 aa) |
| | CDC73 | Cell division cycle 73. (536 aa) |
| | ZNRF3 | Zinc and ring finger 3. (810 aa) |
| | AXIN1 | Axin 1. (864 aa) |
| | DIXDC1 | DIX domain containing 1. (688 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (197 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | G3TVD3_LOXAF | EF-hand domain-containing protein. (102 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | ETV2 | ETS variant 2. (336 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (185 aa) |
| | AXIN2 | Axin 2. (820 aa) |
| | PTK7 | Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1061 aa) |
| | RSPO4 | R-spondin 4. (229 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (295 aa) |
| | VANGL2 | Vang-like protein. (575 aa) |
| | HBP1 | HMG-box transcription factor 1. (515 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (282 aa) |
| | DISC1 | Uncharacterized protein. (232 aa) |
| | KREMEN2 | Kringle containing transmembrane protein 2. (461 aa) |
| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (385 aa) |
| | GPC3 | Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (472 aa) |
| | FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (503 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1605 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | DLX3 | Distal-less homeobox 3. (292 aa) |
| | FZD1 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (629 aa) |
| | CELSR2 | Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2919 aa) |
| | G3UA64_LOXAF | Bromo domain-containing protein. (474 aa) |
| | CXXC4 | CXXC finger protein 4. (205 aa) |
| | BRD7 | Bromo domain-containing protein. (652 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (593 aa) |
| | TRABD2B | Uncharacterized protein. (222 aa) |
| | PORCN | Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (437 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (536 aa) |
| | IFT80 | Intraflagellar transport 80. (778 aa) |
| | LY6G5B | Uncharacterized protein. (194 aa) |
| | G3UFV4_LOXAF | Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (112 aa) |
| | TLE2 | TLE family member 2, transcriptional corepressor. (767 aa) |
| | EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (425 aa) |
| | TLE1 | TLE family member 1, transcriptional corepressor. (780 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (621 aa) |
| | RNF146 | Ring finger protein 146. (361 aa) |
| | FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (513 aa) |
| | BCL9L | Uncharacterized protein. (690 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (445 aa) |
| | C12orf43 | Chromosome 12 open reading frame 43. (262 aa) |
| | SOSTDC1 | Sclerostin domain containing 1. (206 aa) |
| | G3UMP2_LOXAF | Uncharacterized protein. (193 aa) |
| | CPZ | Peptidase_M14 domain-containing protein. (332 aa) |
| | SOST | Sclerostin. (213 aa) |
| | G3UNE7_LOXAF | Uncharacterized protein. (214 aa) |
