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HSD3B2 HSD3B2 TOP3A TOP3A P4HB P4HB PUS7L PUS7L HYI HYI DEGS1 DEGS1 RPUSD1 RPUSD1 TRUB2 TRUB2 DCT DCT MIF MIF PGM2L1 PGM2L1 PMM2 PMM2 KATNAL1 KATNAL1 LSS LSS FKBP3 FKBP3 PTGDS PTGDS IDI1 IDI1 MMUT MMUT GNPDA1 GNPDA1 ISYNA1 ISYNA1 FKBP11 FKBP11 FKBP5 FKBP5 TXNDC16 TXNDC16 DDTL DDTL ENOX1 ENOX1 KATNAL2 KATNAL2 MCEE MCEE RPIA RPIA PGM1 PGM1 PGM2 PGM2 KATNA1 KATNA1 PTGES2 PTGES2 ERP27 ERP27 PGM3 PGM3 FKBP1B FKBP1B RPUSD4 RPUSD4 AIP AIP G3SW83_LOXAF G3SW83_LOXAF TBXAS1 TBXAS1 CFTR CFTR QSOX2 QSOX2 IDI2 IDI2 RENBP RENBP PDIA4 PDIA4 PDIA2 PDIA2 CRELD2 CRELD2 PGAM2 PGAM2 PGAM4 PGAM4 PDIA3 PDIA3 PPIC PPIC NAXE NAXE TXNDC5 TXNDC5 FKBP1A FKBP1A G3U0Q5_LOXAF G3U0Q5_LOXAF PPIL1 PPIL1 G3TZG9_LOXAF G3TZG9_LOXAF SRR SRR TXNDC15 TXNDC15 PPIA PPIA FKBP14 FKBP14 PIN1 PIN1 MPI MPI HPGDS HPGDS BPGM BPGM GSTZ1 GSTZ1 PPIG PPIG PTGES3 PTGES3 FKBP15 FKBP15 PPIE PPIE FUOM FUOM ENOPH1 ENOPH1 FKBP8 FKBP8 FKBP2 FKBP2 DSE DSE QSOX1 QSOX1 EHHADH EHHADH PPIL3 PPIL3 GLCE GLCE TSTA3 TSTA3 PUS10 PUS10 GNPDA2 GNPDA2 TTC9C TTC9C PPWD1 PPWD1 MRI1 MRI1 PBLD PBLD PDIA5 PDIA5 ITPK1 ITPK1 PUSL1 PUSL1 GPI GPI TMX3 TMX3 ITGB3 ITGB3 PPID PPID SPO11 SPO11 PTGES PTGES TRUB1 TRUB1 RPUSD2 RPUSD2 CUNH11orf80 CUNH11orf80 TOP2B TOP2B PPIH PPIH FKBP7 FKBP7 PPIL2 PPIL2 PMM1 PMM1 ECI2 ECI2 ENOSF1 ENOSF1 NKTR NKTR FKBP4 FKBP4 LOC100655872 LOC100655872 GALM GALM TPI1 TPI1 TOP1 TOP1 PTPA PTPA TTC9B TTC9B RPE RPE FKBP9 FKBP9 FKBP10 FKBP10 CUNH2orf16 CUNH2orf16 PPIB PPIB TOP3B TOP3B G3TL25_LOXAF G3TL25_LOXAF PIN4 PIN4 THAP4 THAP4 EBPL EBPL AIPL1 AIPL1 ECHS1 ECHS1 GNE GNE LENG1 LENG1 RPUSD3 RPUSD3 PUS7 PUS7 GALE GALE AMACR AMACR HSD17B4 HSD17B4 CWC27 CWC27 G3UH85_LOXAF G3UH85_LOXAF PDILT PDILT LOC100659162 LOC100659162 PDIA6 PDIA6 TTC9 TTC9 LRR1 LRR1 TOP2A TOP2A G3UJB1_LOXAF G3UJB1_LOXAF PTGIS PTGIS ERP44 ERP44 DSEL DSEL G3ULH8_LOXAF G3ULH8_LOXAF PPIL4 PPIL4 PUS1 PUS1 HSPD1 HSPD1 DKC1 DKC1 PPIF PPIF PUS3 PUS3 ECI1 ECI1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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HSD3B23Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (367 aa)
TOP3ADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1008 aa)
P4HBProtein disulfide-isomerase. (509 aa)
PUS7LPseudouridine synthase 7 like. (702 aa)
HYIPutative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family. (277 aa)
DEGS1Delta 4-desaturase, sphingolipid 1. (296 aa)
RPUSD1RNA pseudouridine synthase domain containing 1. (302 aa)
TRUB2TruB pseudouridine synthase family member 2. (303 aa)
DCTDopachrome tautomerase. (460 aa)
MIFMacrophage migration inhibitory factor. (114 aa)
PGM2L1Phosphoglucomutase 2 like 1. (622 aa)
PMM2Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (243 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
LSSTerpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (734 aa)
FKBP3Peptidylprolyl isomerase. (224 aa)
PTGDSLipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (191 aa)
IDI1Isopentenyl-diphosphate delta isomerase 1. (227 aa)
MMUTMethylmalonyl-CoA mutase. (750 aa)
GNPDA1Glucosamine-6-phosphate isomerase. (289 aa)
ISYNA1Inositol-3-phosphate synthase 1. (464 aa)
FKBP11Peptidylprolyl isomerase. (198 aa)
FKBP5Peptidylprolyl isomerase. (457 aa)
TXNDC16Thioredoxin domain containing 16. (822 aa)
DDTLD-dopachrome tautomerase like. (118 aa)
ENOX1Ecto-NOX disulfide-thiol exchanger 1. (663 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (405 aa)
MCEEMethylmalonyl-CoA epimerase. (164 aa)
RPIARibose 5-phosphate isomerase A. (310 aa)
PGM1Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. (580 aa)
PGM2Phosphoglucomutase 2. (616 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (496 aa)
PTGES2Prostaglandin E synthase 2; Belongs to the GST superfamily. (363 aa)
ERP27Endoplasmic reticulum protein 27. (273 aa)
PGM3Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family. (546 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
RPUSD4RNA pseudouridine synthase D4. (376 aa)
AIPPeptidylprolyl isomerase. (330 aa)
G3SW83_LOXAFEXPERA domain-containing protein. (232 aa)
TBXAS1Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (533 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1479 aa)
QSOX2Sulfhydryl oxidase. (609 aa)
IDI2Isopentenyl-diphosphate delta isomerase 2. (227 aa)
RENBPRenin binding protein. (412 aa)
PDIA4Protein disulfide isomerase family A member 4; Belongs to the protein disulfide isomerase family. (617 aa)
PDIA2Protein disulfide isomerase family A member 2. (467 aa)
CRELD2Cysteine rich with EGF like domains 2. (311 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (262 aa)
PGAM4Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
PDIA3Protein disulfide-isomerase. (505 aa)
PPICPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (213 aa)
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (288 aa)
TXNDC5Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (344 aa)
FKBP1APeptidylprolyl isomerase. (137 aa)
G3U0Q5_LOXAFUncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (324 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
G3TZG9_LOXAFUncharacterized protein. (171 aa)
SRRSerine racemase. (334 aa)
TXNDC15Thioredoxin domain containing 15. (355 aa)
PPIAPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (206 aa)
FKBP14Peptidylprolyl isomerase. (211 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
MPIMannose-6-phosphate isomerase. (422 aa)
HPGDSHematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa)
BPGMPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa)
GSTZ1Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (216 aa)
PPIGPeptidylprolyl isomerase G. (755 aa)
PTGES3CS domain-containing protein. (159 aa)
FKBP15Peptidylprolyl isomerase. (1201 aa)
PPIEPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (286 aa)
FUOMFucose mutarotase. (151 aa)
ENOPH1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa)
FKBP8Peptidylprolyl isomerase. (405 aa)
FKBP2Peptidylprolyl isomerase. (140 aa)
DSEDermatan sulfate epimerase. (955 aa)
QSOX1Sulfhydryl oxidase. (751 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
PPIL3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (160 aa)
GLCEGlucuronic acid epimerase. (616 aa)
TSTA3Tissue specific transplantation antigen P35B. (321 aa)
PUS10Pseudouridine synthase 10. (534 aa)
GNPDA2Glucosamine-6-phosphate deaminase 2. (277 aa)
TTC9CTetratricopeptide repeat domain 9C. (171 aa)
PPWD1Peptidylprolyl isomerase domain and WD repeat containing 1. (644 aa)
MRI1Methylthioribose-1-phosphate isomerase 1; Belongs to the eIF-2B alpha/beta/delta subunits family. (312 aa)
PBLDPhenazine biosynthesis like protein domain containing. (288 aa)
PDIA5Protein disulfide isomerase family A member 5. (518 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (414 aa)
PUSL1tRNA pseudouridine synthase. (266 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
TMX3Thioredoxin related transmembrane protein 3. (420 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (778 aa)
PPIDPeptidylprolyl isomerase D. (372 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (396 aa)
PTGESProstaglandin E synthase. (153 aa)
TRUB1TruB pseudouridine synthase family member 1. (350 aa)
RPUSD2RNA pseudouridine synthase domain containing 2. (529 aa)
CUNH11orf80Uncharacterized protein. (409 aa)
TOP2BDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1604 aa)
PPIHPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
FKBP7Peptidylprolyl isomerase. (211 aa)
PPIL2Peptidylprolyl isomerase like 2. (522 aa)
PMM1Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (264 aa)
ECI2Enoyl-CoA delta isomerase 2. (390 aa)
ENOSF1Enolase superfamily member 1. (443 aa)
NKTRNatural killer cell triggering receptor. (1447 aa)
FKBP4Peptidylprolyl isomerase. (420 aa)
LOC100655872Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (329 aa)
GALMAldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (342 aa)
TPI1Triosephosphate isomerase. (249 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (770 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (324 aa)
TTC9BTetratricopeptide repeat domain 9B. (236 aa)
RPERibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (235 aa)
FKBP9Peptidylprolyl isomerase. (572 aa)
FKBP10Peptidylprolyl isomerase. (582 aa)
CUNH2orf16Uncharacterized protein. (563 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
TOP3BDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (862 aa)
G3TL25_LOXAFUncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (329 aa)
PIN4Peptidyl-prolyl cis-trans isomerase. (131 aa)
THAP4THAP domain containing 4. (574 aa)
EBPLEBP like. (149 aa)
AIPL1Aryl hydrocarbon receptor interacting protein like 1. (328 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
GNEGlucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase. (752 aa)
LENG1Leukocyte receptor cluster member 1. (256 aa)
RPUSD3RNA pseudouridine synthase D3. (344 aa)
PUS7Pseudouridine synthase 7. (673 aa)
GALEUDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (348 aa)
AMACRAlpha-methylacyl-CoA racemase. (384 aa)
HSD17B4MaoC_dehydrat_N domain-containing protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (500 aa)
CWC27CWC27 spliceosome associated cyclophilin. (472 aa)
G3UH85_LOXAFPPIase cyclophilin-type domain-containing protein. (139 aa)
PDILTProtein disulfide isomerase like, testis expressed. (575 aa)
LOC100659162Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
PDIA6Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (446 aa)
TTC9Tetratricopeptide repeat domain 9. (182 aa)
LRR1Leucine rich repeat protein 1. (425 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1537 aa)
G3UJB1_LOXAFPeptidylprolyl isomerase. (224 aa)
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (438 aa)
ERP44Endoplasmic reticulum protein 44. (407 aa)
DSELDermatan sulfate epimerase like. (1212 aa)
G3ULH8_LOXAFDUF3699 domain-containing protein. (585 aa)
PPIL4Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (493 aa)
PUS1Pseudouridine synthase 1. (370 aa)
HSPD1Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa)
DKC1Dyskerin pseudouridine synthase 1. (514 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (206 aa)
PUS3Pseudouridine synthase 3. (480 aa)
ECI1Enoyl-CoA delta isomerase 1. (233 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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