STRINGSTRING
LYN LYN REPS1 REPS1 CBL CBL HIP1R HIP1R KHDRBS2 KHDRBS2 ELMO3 ELMO3 RAD9B RAD9B AFAP1L2 AFAP1L2 WASF2 WASF2 GRB2 GRB2 CYBA CYBA KHDRBS3 KHDRBS3 EVL EVL ADAM10 ADAM10 DNM2 DNM2 INPP5J INPP5J HCLS1 HCLS1 QKI QKI ARHGAP17 ARHGAP17 ELMO2 ELMO2 ZNF106 ZNF106 MICAL1 MICAL1 ITGB1BP2 ITGB1BP2 INPPL1 INPPL1 CD2AP CD2AP ARHGAP27 ARHGAP27 SHANK3 SHANK3 G3UB08_LOXAF G3UB08_LOXAF VASP VASP G3U940_LOXAF G3U940_LOXAF WIPF1 WIPF1 PLSCR3 PLSCR3 ENAH ENAH ABI3 ABI3 G3U6T3_LOXAF G3U6T3_LOXAF G3U5I3_LOXAF G3U5I3_LOXAF OSTF1 OSTF1 WAS WAS CRK CRK G3TY27_LOXAF G3TY27_LOXAF BCAR1 BCAR1 ARHGAP31 ARHGAP31 ADAM19 ADAM19 G3TV61_LOXAF G3TV61_LOXAF DNAJC6 DNAJC6 PTPN6 PTPN6 G3TU53_LOXAF G3TU53_LOXAF DNM1 DNM1 CBLC CBLC LANCL1 LANCL1 SHANK2 SHANK2 ADAM15 ADAM15 ELMO1 ELMO1 ABI1 ABI1 NCF1 NCF1 SH3BP2 SH3BP2 UVRAG UVRAG INPP5D INPP5D CASP9 CASP9 RUFY1 RUFY1 ENKUR ENKUR ABI2 ABI2 SH3BP5 SH3BP5 CBLB CBLB FUT8 FUT8 DRD4 DRD4 SH3BGRL2 SH3BGRL2 PRRT2 PRRT2 PTPN12 PTPN12 SGIP1 SGIP1 AKAP5 AKAP5 AFAP1 AFAP1 AFAP1L1 AFAP1L1 SH3KBP1 SH3KBP1 G3TBG1_LOXAF G3TBG1_LOXAF ERRFI1 ERRFI1 SH3BGRL SH3BGRL G3TAY3_LOXAF G3TAY3_LOXAF DPYSL3 DPYSL3 RUFY2 RUFY2 SYNJ2 SYNJ2 TOM1L1 TOM1L1 SYNJ1 SYNJ1 DENND1A DENND1A EFS EFS PTTG1 PTTG1 G3T6R6_LOXAF G3T6R6_LOXAF SOS1 SOS1 SH3BP1 SH3BP1 ADAM17 ADAM17 KHDRBS1 KHDRBS1 MYPN MYPN SH2D2A SH2D2A RAD9A RAD9A PTPN22 PTPN22 DAB2IP DAB2IP MVB12A MVB12A SYNGAP1 SYNGAP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LYNTyrosine-protein kinase. (512 aa)
REPS1RALBP1 associated Eps domain containing 1. (745 aa)
CBLCbl proto-oncogene. (906 aa)
HIP1RHuntingtin interacting protein 1 related. (1065 aa)
KHDRBS2KH RNA binding domain containing, signal transduction associated 2. (349 aa)
ELMO3Engulfment and cell motility 3. (731 aa)
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (406 aa)
AFAP1L2Actin filament associated protein 1 like 2. (836 aa)
WASF2WASP family member 2. (497 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CYBACytochrome b-245 alpha chain. (169 aa)
KHDRBS3KH RNA binding domain containing, signal transduction associated 3. (333 aa)
EVLEnah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (405 aa)
ADAM10ADAM metallopeptidase domain 10. (639 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (817 aa)
INPP5JInositol polyphosphate-5-phosphatase J. (1009 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (487 aa)
QKIQKI, KH domain containing RNA binding. (306 aa)
ARHGAP17Rho GTPase activating protein 17. (880 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
ZNF106Zinc finger protein 106. (1881 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1048 aa)
ITGB1BP2Integrin subunit beta 1 binding protein 2. (347 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1265 aa)
CD2APCD2 associated protein. (641 aa)
ARHGAP27Rho GTPase activating protein 27. (746 aa)
SHANK3ANK_REP_REGION domain-containing protein. (342 aa)
G3UB08_LOXAFUncharacterized protein. (319 aa)
VASPVasodilator stimulated phosphoprotein. (484 aa)
G3U940_LOXAFUncharacterized protein. (318 aa)
WIPF1WAS/WASL interacting protein family member 1. (505 aa)
PLSCR3Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (295 aa)
ENAHENAH actin regulator. (789 aa)
ABI3ABI family member 3. (369 aa)
G3U6T3_LOXAFUncharacterized protein. (340 aa)
G3U5I3_LOXAFUncharacterized protein. (237 aa)
OSTF1Osteoclast stimulating factor 1. (216 aa)
WASWASP actin nucleation promoting factor. (502 aa)
CRKCRK proto-oncogene, adaptor protein. (307 aa)
G3TY27_LOXAFUncharacterized protein. (77 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (869 aa)
ARHGAP31Rho GTPase activating protein 31. (1420 aa)
ADAM19EGF-like domain-containing protein. (319 aa)
G3TV61_LOXAFUncharacterized protein. (419 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (957 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
G3TU53_LOXAFUncharacterized protein. (821 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (845 aa)
CBLCCbl proto-oncogene C. (503 aa)
LANCL1LanC like 1. (399 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1441 aa)
ADAM15ADAM metallopeptidase domain 15. (864 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
ABI1Abl interactor 1. (481 aa)
NCF1Neutrophil cytosolic factor 1. (409 aa)
SH3BP2SH3 domain binding protein 2. (563 aa)
UVRAGC2 domain-containing protein. (369 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1191 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (450 aa)
RUFY1RUN and FYVE domain containing 1. (689 aa)
ENKUREnkurin, TRPC channel interacting protein. (256 aa)
ABI2Abl interactor 2. (513 aa)
SH3BP5SH3 domain binding protein 5. (388 aa)
CBLBCbl proto-oncogene B. (983 aa)
FUT8Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (575 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (356 aa)
SH3BGRL2SH3 domain-binding glutamic acid-rich-like protein; Belongs to the SH3BGR family. (103 aa)
PRRT2Uncharacterized protein. (403 aa)
PTPN12Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (774 aa)
SGIP1SH3 domain GRB2 like endophilin interacting protein 1. (839 aa)
AKAP5A-kinase anchoring protein 5. (422 aa)
AFAP1Actin filament associated protein 1. (547 aa)
AFAP1L1Actin filament associated protein 1 like 1. (809 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (707 aa)
G3TBG1_LOXAFWH2 domain-containing protein. (213 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (458 aa)
SH3BGRLSH3 domain-binding glutamic acid-rich-like protein; Belongs to the SH3BGR family. (113 aa)
G3TAY3_LOXAFUncharacterized protein. (392 aa)
DPYSL3Dihydropyrimidinase like 3. (660 aa)
RUFY2RUN and FYVE domain containing 2. (606 aa)
SYNJ2Synaptojanin 2. (1467 aa)
TOM1L1Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. (475 aa)
SYNJ1Synaptojanin 1. (1581 aa)
DENND1AUncharacterized protein. (641 aa)
EFSEmbryonal Fyn-associated substrate. (562 aa)
PTTG1Uncharacterized protein. (191 aa)
G3T6R6_LOXAFUncharacterized protein. (488 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1316 aa)
SH3BP1Uncharacterized protein. (611 aa)
ADAM17ADAM metallopeptidase domain 17. (845 aa)
KHDRBS1KH RNA binding domain containing, signal transduction associated 1. (386 aa)
MYPNMyopalladin. (1317 aa)
SH2D2ASH2 domain containing 2A. (386 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (390 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (811 aa)
DAB2IPDAB2 interacting protein. (1189 aa)
MVB12AMultivesicular body subunit 12A. (271 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1067 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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