STRINGSTRING
EGR2 EGR2 G3SXL2_LOXAF G3SXL2_LOXAF PHF20L1 PHF20L1 KAT14 KAT14 VIPAS39 VIPAS39 SENP7 SENP7 OGFOD2 OGFOD2 BEND3 BEND3 SUV39H1 SUV39H1 SUPT3H SUPT3H MRGBP MRGBP UBE2I UBE2I MYOD1 MYOD1 LOXL3 LOXL3 SETD3 SETD3 DYDC1 DYDC1 MAP3K7 MAP3K7 CTH CTH MEAF6 MEAF6 KMT2B KMT2B DPY30 DPY30 GCC1 GCC1 BRPF3 BRPF3 LDB1 LDB1 SUV39H2 SUV39H2 LOXL2 LOXL2 FKBP10 FKBP10 ANTKMT ANTKMT MSL3 MSL3 RFPL4B RFPL4B SUMO1 SUMO1 SIRT2 SIRT2 TRPM4 TRPM4 RNF212B RNF212B ATPSCKMT ATPSCKMT SETD1A SETD1A MLLT6 MLLT6 PCGF2 PCGF2 PWP1 PWP1 SMYD2 SMYD2 KANSL2 KANSL2 EPC2 EPC2 METTL18 METTL18 NCOA1 NCOA1 POLE3 POLE3 NSMCE2 NSMCE2 SPHK2 SPHK2 EP400 EP400 LOX LOX GTF3C4 GTF3C4 PAX6 PAX6 GCSH GCSH CREBBP CREBBP KAT5 KAT5 RLF RLF ZMPSTE24 ZMPSTE24 WDR5B WDR5B TAF12 TAF12 ZNF335 ZNF335 MECP2 MECP2 BRPF1 BRPF1 LEF1 LEF1 NFYA NFYA TRIM16 TRIM16 G3THQ5_LOXAF G3THQ5_LOXAF METTL21A METTL21A ATAT1 ATAT1 VCPKMT VCPKMT WDR82 WDR82 DMRTC2 DMRTC2 SETD1B SETD1B LOXL1 LOXL1 JMJD6 JMJD6 KIAA2013 KIAA2013 RUVBL1 RUVBL1 TET3 TET3 TADA3 TADA3 DR1 DR1 RTF1 RTF1 NCOA6 NCOA6 HNF1A HNF1A CAMKMT CAMKMT PIAS1 PIAS1 SMC5 SMC5 G3SVD7_LOXAF G3SVD7_LOXAF ING5 ING5 G3UN99_LOXAF G3UN99_LOXAF G3UMU6_LOXAF G3UMU6_LOXAF LOC100661536 LOC100661536 SIRT7 SIRT7 SENP3 SENP3 TET2 TET2 DOT1L DOT1L KMT2A KMT2A SENP2 SENP2 IZUMO4 IZUMO4 RANGAP1 RANGAP1 SETD7 SETD7 RBBP5 RBBP5 MLLT1 MLLT1 G3UH36_LOXAF G3UH36_LOXAF ACTL6B ACTL6B G3UFS4_LOXAF G3UFS4_LOXAF G3UF27_LOXAF G3UF27_LOXAF PLOD1 PLOD1 NAA40 NAA40 G3UE49_LOXAF G3UE49_LOXAF EEF1AKMT3 EEF1AKMT3 SUMO2 SUMO2 ATXN7L3 ATXN7L3 APBB1 APBB1 CRTC2 CRTC2 G3UBZ7_LOXAF G3UBZ7_LOXAF KAT6B KAT6B BRD8 BRD8 PBXIP1 PBXIP1 G3U994_LOXAF G3U994_LOXAF SENP6 SENP6 PAGR1 PAGR1 SENP5 SENP5 PLOD3 PLOD3 G3U6X7_LOXAF G3U6X7_LOXAF TAF6L TAF6L CXXC1 CXXC1 TRIM28 TRIM28 TAF10 TAF10 SIRT3 SIRT3 TADA2A TADA2A G3U343_LOXAF G3U343_LOXAF ARID4B ARID4B HDAC10 HDAC10 TAF1 TAF1 G3U120_LOXAF G3U120_LOXAF G3U0S4_LOXAF G3U0S4_LOXAF RUVBL2 RUVBL2 TAF5L TAF5L G3U019_LOXAF G3U019_LOXAF PIAS2 PIAS2 MORF4L2 MORF4L2 ATXN7L2 ATXN7L2 MEN1 MEN1 SGF29 SGF29 ESCO1 ESCO1 TAF5 TAF5 ETFBKMT ETFBKMT KAT6A KAT6A MSL2 MSL2 DHPS DHPS G3TWI0_LOXAF G3TWI0_LOXAF KANSL1 KANSL1 ING3 ING3 DESI1 DESI1 KDM3A KDM3A GTF2B GTF2B LIPT2 LIPT2 CTR9 CTR9 MBIP MBIP EEF1AKMT1 EEF1AKMT1 TAF2 TAF2 TAF6 TAF6 VPS72 VPS72 ACTL6A ACTL6A TRRAP TRRAP UBA2 UBA2 RNF113A RNF113A KAT8 KAT8 EOMES EOMES NAA50 NAA50 SETDB1 SETDB1 SETD4 SETD4 TEX30 TEX30 METTL21C METTL21C PARK7 PARK7 LIAS LIAS DOHH DOHH EHMT1 EHMT1 EPC1 EPC1 KMT5A KMT5A SETDB2 SETDB2 TRIM27 TRIM27 EP300 EP300 ZZZ3 ZZZ3 BLOC1S1 BLOC1S1 FOXP3 FOXP3 SETBP1 SETBP1 MCM3AP MCM3AP SETD2 SETD2 ENY2 ENY2 MCRS1 MCRS1 WDR61 WDR61 BCL11A BCL11A KAT7 KAT7 PML PML BRCA2 BRCA2 EYA1 EYA1 TRIM38 TRIM38 SIRT4 SIRT4 ASH1L ASH1L ASH2L ASH2L MLLT3 MLLT3 G3SPK1_LOXAF G3SPK1_LOXAF PLOD2 PLOD2 TAF4 TAF4 SAE1 SAE1 EZH2 EZH2 N6AMT1 N6AMT1 LOXL4 LOXL4 NFYC NFYC NDUFAB1 NDUFAB1 JADE2 JADE2 JADE1 JADE1 RANBP2 RANBP2 UHRF2 UHRF2 NCOA3 NCOA3 YEATS4 YEATS4 BRD1 BRD1 MUL1 MUL1 DMAP1 DMAP1 SETD6 SETD6 PNO1 PNO1 WDR5 WDR5 SUPT7L SUPT7L VPS33B VPS33B G3T5M6_LOXAF G3T5M6_LOXAF G3T5M5_LOXAF G3T5M5_LOXAF EZH1 EZH1 YEATS2 YEATS2 PHF20 PHF20 HAT1 HAT1 MSL1 MSL1 KMT2D KMT2D SENP1 SENP1 IFIH1 IFIH1 G3T4Q6_LOXAF G3T4Q6_LOXAF MORF4L1 MORF4L1 TADA1 TADA1 BAG6 BAG6 SMYD5 SMYD5 SIRT1 SIRT1 PIAS4 PIAS4 SETD5 SETD5 ATXN7L1 ATXN7L1 OGT OGT ARID4A ARID4A MED24 MED24 JADE3 JADE3 HDAC6 HDAC6 ING4 ING4 PIAS3 PIAS3 EHMT2 EHMT2 NSD2 NSD2 KAT2A KAT2A KMT2C KMT2C SMYD1 SMYD1 MBTD1 MBTD1 USPL1 USPL1 EEF1AKMT2 EEF1AKMT2 SIRT5 SIRT5 ZNF451 ZNF451 C6orf136 C6orf136 KANSL3 KANSL3 P3H3 P3H3 PRDM5 PRDM5 KMT5B KMT5B ATF2 ATF2 CHD5 CHD5 KAT2B KAT2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EGR2Early growth response 2. (472 aa)
G3SXL2_LOXAFUncharacterized protein. (242 aa)
PHF20L1PHD finger protein 20 like 1. (1021 aa)
KAT14Lysine acetyltransferase 14. (771 aa)
VIPAS39VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog. (494 aa)
SENP7SUMO specific peptidase 7. (952 aa)
OGFOD22-oxoglutarate and iron dependent oxygenase domain containing 2. (350 aa)
BEND3BEN domain containing 3. (828 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (364 aa)
SUPT3HSPT3 homolog, SAGA and STAGA complex component. (326 aa)
MRGBPMRG domain binding protein. (204 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
LOXL3Lysyl oxidase like 3. (746 aa)
SETD3Protein-histidine N-methyltransferase. (598 aa)
DYDC1DPY30 domain containing 1. (175 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
CTHCystathionine gamma-lyase. (397 aa)
MEAF6MYST/Esa1 associated factor 6. (169 aa)
KMT2BLysine methyltransferase 2B. (2303 aa)
DPY30Dpy-30 histone methyltransferase complex regulatory subunit. (99 aa)
GCC1GRIP and coiled-coil domain containing 1. (774 aa)
BRPF3Bromodomain and PHD finger containing 3. (1201 aa)
LDB1LIM domain binding 1. (411 aa)
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (403 aa)
LOXL2Lysyl oxidase like 2. (772 aa)
FKBP10Peptidylprolyl isomerase. (582 aa)
ANTKMTAdenine nucleotide translocase lysine methyltransferase. (207 aa)
MSL3MSL complex subunit 3. (334 aa)
RFPL4BUncharacterized protein. (296 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (392 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1139 aa)
RNF212BRing finger protein 212B. (263 aa)
ATPSCKMTATP synthase c subunit lysine N-methyltransferase. (215 aa)
SETD1ASET domain containing 1A, histone lysine methyltransferase. (1691 aa)
MLLT6MLLT6, PHD finger containing. (1049 aa)
PCGF2Polycomb group ring finger 2. (343 aa)
PWP1PWP1 homolog, endonuclein. (500 aa)
SMYD2SET and MYND domain containing 2. (430 aa)
KANSL2KAT8 regulatory NSL complex subunit 2. (488 aa)
EPC2Enhancer of polycomb homolog. (784 aa)
METTL18Methyltransferase like 18. (372 aa)
NCOA1Nuclear receptor coactivator. (1444 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (96 aa)
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (245 aa)
SPHK2Sphingosine kinase 2. (615 aa)
EP400E1A binding protein p400. (3005 aa)
LOXLysyl oxidase. (415 aa)
GTF3C4General transcription factor IIIC subunit 4. (821 aa)
PAX6Paired box 6. (436 aa)
GCSHGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (171 aa)
CREBBPCREB binding protein. (2433 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (545 aa)
RLFRearranged L-myc fusion. (1915 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
WDR5BWD repeat domain 5B. (330 aa)
TAF12TATA-box binding protein associated factor 12. (213 aa)
ZNF335Zinc finger protein 335. (1345 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (469 aa)
BRPF1Bromodomain and PHD finger containing 1. (1248 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
NFYANuclear transcription factor Y subunit alpha. (347 aa)
TRIM16Uncharacterized protein. (549 aa)
G3THQ5_LOXAFRING-type domain-containing protein. (330 aa)
METTL21AMethyltransferase like 21A. (218 aa)
ATAT1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (422 aa)
VCPKMTValosin containing protein lysine methyltransferase. (229 aa)
WDR82WD repeat domain 82. (312 aa)
DMRTC2DMRT like family C2. (412 aa)
SETD1BSET domain containing 1B, histone lysine methyltransferase. (1772 aa)
LOXL1Lysyl oxidase like 1. (596 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (367 aa)
KIAA2013KIAA2013. (627 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
TET3Tet_JBP domain-containing protein. (693 aa)
TADA3Transcriptional adaptor 3. (432 aa)
DR1Down-regulator of transcription 1. (176 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (711 aa)
NCOA6Nuclear receptor coactivator 6. (2056 aa)
HNF1AHNF1 homeobox A. (631 aa)
CAMKMTCalmodulin-lysine N-methyltransferase. (197 aa)
PIAS1Protein inhibitor of activated STAT 1. (642 aa)
SMC5SMC_N domain-containing protein. (1101 aa)
G3SVD7_LOXAFUncharacterized protein. (241 aa)
ING5Inhibitor of growth family member 5. (228 aa)
G3UN99_LOXAFSmall ubiquitin-related modifier. (100 aa)
G3UMU6_LOXAFUncharacterized protein. (474 aa)
LOC100661536Uncharacterized protein. (307 aa)
SIRT7Sirtuin 7. (329 aa)
SENP3ULP_PROTEASE domain-containing protein. (567 aa)
TET2Tet_JBP domain-containing protein. (183 aa)
DOT1LHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1546 aa)
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3964 aa)
SENP2SUMO specific peptidase 2. (589 aa)
IZUMO4IZUMO family member 4. (232 aa)
RANGAP1Ran GTPase activating protein 1. (602 aa)
SETD7Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes. (366 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (541 aa)
MLLT1MLLT1 super elongation complex subunit. (553 aa)
G3UH36_LOXAFBromo domain-containing protein. (277 aa)
ACTL6BActin like 6B; Belongs to the actin family. (373 aa)
G3UFS4_LOXAFUncharacterized protein. (259 aa)
G3UF27_LOXAFSET domain-containing protein. (338 aa)
PLOD1Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (772 aa)
NAA40N(alpha)-acetyltransferase 40, NatD catalytic subunit. (238 aa)
G3UE49_LOXAFSmall ubiquitin-related modifier. (95 aa)
EEF1AKMT3EEF1A lysine methyltransferase 3. (225 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (352 aa)
APBB1Amyloid beta precursor protein binding family B member 1. (708 aa)
CRTC2CREB regulated transcription coactivator 2. (689 aa)
G3UBZ7_LOXAFUncharacterized protein. (634 aa)
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1699 aa)
BRD8Bromodomain containing 8. (953 aa)
PBXIP1PBX homeobox interacting protein 1. (704 aa)
G3U994_LOXAFSmall ubiquitin-related modifier. (95 aa)
SENP6SUMO specific peptidase 6. (1134 aa)
PAGR1PAXIP1 associated glutamate rich protein 1. (250 aa)
SENP5SUMO specific peptidase 5. (756 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (741 aa)
G3U6X7_LOXAFUncharacterized protein. (267 aa)
TAF6LTATA-box binding protein associated factor 6 like. (621 aa)
CXXC1CXXC finger protein 1. (466 aa)
TRIM28Tripartite motif containing 28. (785 aa)
TAF10Uncharacterized protein. (108 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (257 aa)
TADA2ATranscriptional adapter. (441 aa)
G3U343_LOXAFUncharacterized protein. (176 aa)
ARID4BAT-rich interaction domain 4B. (1312 aa)
HDAC10Histone deacetylase 10. (652 aa)
TAF1Transcription initiation factor TFIID subunit. (1898 aa)
G3U120_LOXAFUncharacterized protein. (764 aa)
G3U0S4_LOXAFUncharacterized protein. (1523 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (461 aa)
TAF5LTATA-box binding protein associated factor 5 like. (589 aa)
G3U019_LOXAFThiF domain-containing protein. (422 aa)
PIAS2Protein inhibitor of activated STAT 2. (621 aa)
MORF4L2Mortality factor 4 like 2. (288 aa)
ATXN7L2Ataxin 7 like 2. (719 aa)
MEN1Menin 1. (616 aa)
SGF29SAGA complex associated factor 29. (293 aa)
ESCO1Establishment of sister chromatid cohesion N-acetyltransferase 1. (846 aa)
TAF5TATA-box binding protein associated factor 5. (801 aa)
ETFBKMTElectron transfer flavoprotein subunit beta lysine methyltransferase. (266 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2016 aa)
MSL2MSL complex subunit 2. (602 aa)
DHPSUncharacterized protein. (369 aa)
G3TWI0_LOXAFN-acetyltransferase domain-containing protein. (222 aa)
KANSL1KAT8 regulatory NSL complex subunit 1. (1103 aa)
ING3Inhibitor of growth protein. (418 aa)
DESI1Desumoylating isopeptidase 1. (139 aa)
KDM3AUncharacterized protein. (372 aa)
GTF2BGeneral transcription factor IIB. (316 aa)
LIPT2Lipoyl(octanoyl) transferase 2. (168 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1164 aa)
MBIPMAP3K12 binding inhibitory protein 1. (345 aa)
EEF1AKMT1EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family. (218 aa)
TAF2TATA-box binding protein associated factor 2. (1196 aa)
TAF6TATA-box binding protein associated factor 6. (678 aa)
VPS72Vacuolar protein sorting 72 homolog. (363 aa)
ACTL6AActin like 6A; Belongs to the actin family. (429 aa)
TRRAPUncharacterized protein; Belongs to the PI3/PI4-kinase family. (2909 aa)
UBA2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (639 aa)
RNF113ARing finger protein 113A. (342 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (466 aa)
EOMESEomesodermin. (700 aa)
NAA50N(alpha)-acetyltransferase 50, NatE catalytic subunit. (169 aa)
SETDB1SET domain bifurcated histone lysine methyltransferase 1. (1307 aa)
SETD4SET domain containing 4. (442 aa)
TEX30Testis expressed 30. (225 aa)
METTL21CMethyltransferase like 21C. (234 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa)
DOHHDeoxyhypusine hydroxylase. (209 aa)
EHMT1Euchromatic histone lysine methyltransferase 1. (846 aa)
EPC1Enhancer of polycomb homolog. (842 aa)
KMT5ALysine methyltransferase 5A. (317 aa)
SETDB2SET domain bifurcated histone lysine methyltransferase 2. (711 aa)
TRIM27Tripartite motif containing 27. (615 aa)
EP300E1A binding protein p300. (2420 aa)
ZZZ3Uncharacterized protein. (909 aa)
BLOC1S1Uncharacterized protein. (125 aa)
FOXP3Forkhead box P3. (427 aa)
SETBP1SET binding protein 1. (1280 aa)
MCM3APNupH_GANP domain-containing protein. (504 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (1941 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (99 aa)
MCRS1Microspherule protein 1. (463 aa)
WDR61WD repeat domain 61. (305 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (835 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (613 aa)
PMLPromyelocytic leukemia. (861 aa)
BRCA2BRCA2 DNA repair associated. (3302 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (591 aa)
TRIM38Tripartite motif containing 38. (469 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (312 aa)
ASH1LASH1 like histone lysine methyltransferase. (1974 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (628 aa)
MLLT3MLLT3 super elongation complex subunit. (506 aa)
G3SPK1_LOXAFSmall ubiquitin-related modifier. (87 aa)
PLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (705 aa)
TAF4TATA-box binding protein associated factor 4. (633 aa)
SAE1SUMO1 activating enzyme subunit 1. (346 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
N6AMT1N-6 adenine-specific DNA methyltransferase 1. (214 aa)
LOXL4Lysyl oxidase like 4. (757 aa)
NFYCNuclear transcription factor Y subunit gamma. (336 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa)
JADE2Jade family PHD finger 2. (844 aa)
JADE1Jade family PHD finger 1. (839 aa)
RANBP2RAN binding protein 2. (3072 aa)
UHRF2Ubiquitin like with PHD and ring finger domains 2. (803 aa)
NCOA3Nuclear receptor coactivator. (1413 aa)
YEATS4YEATS domain containing 4. (227 aa)
BRD1Bromodomain containing 1. (1188 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (468 aa)
SETD6N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. (476 aa)
PNO1Partner of NOB1 homolog. (246 aa)
WDR5WD repeat domain 5. (350 aa)
SUPT7LSPT7 like, STAGA complex gamma subunit. (412 aa)
VPS33BUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (613 aa)
G3T5M6_LOXAFN-acetyltransferase domain-containing protein. (227 aa)
G3T5M5_LOXAFN-acetyltransferase domain-containing protein. (227 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (747 aa)
YEATS2YEATS domain containing 2. (1402 aa)
PHF20PHD finger protein 20. (1025 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (422 aa)
MSL1MSL complex subunit 1. (614 aa)
KMT2DLysine methyltransferase 2D. (4936 aa)
SENP1SUMO specific peptidase 1. (666 aa)
IFIH1Interferon induced with helicase C domain 1. (1006 aa)
G3T4Q6_LOXAFJmjC domain-containing protein. (236 aa)
MORF4L1Mortality factor 4 like 1. (362 aa)
TADA1Transcriptional adaptor 1. (335 aa)
BAG6BCL2 associated athanogene 6. (1151 aa)
SMYD5SMYD family member 5. (417 aa)
SIRT1Sirtuin 1. (605 aa)
PIAS4Protein inhibitor of activated STAT 4. (515 aa)
SETD5SET domain containing 5. (1462 aa)
ATXN7L1Ataxin 7 like 1. (860 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
ARID4AAT-rich interaction domain 4A. (1268 aa)
MED24Mediator complex subunit 24. (1008 aa)
JADE3Jade family PHD finger 3. (824 aa)
HDAC6Histone deacetylase 6. (1122 aa)
ING4Inhibitor of growth protein. (249 aa)
PIAS3Protein inhibitor of activated STAT 3. (626 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1225 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1361 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (802 aa)
KMT2CUncharacterized protein. (2177 aa)
SMYD1SET and MYND domain containing 1. (445 aa)
MBTD1Mbt domain containing 1. (632 aa)
USPL1Ubiquitin specific peptidase like 1. (1088 aa)
EEF1AKMT2EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family. (235 aa)
SIRT5Sirtuin 5. (196 aa)
ZNF451Zinc finger protein 451. (1062 aa)
C6orf136Uncharacterized protein. (296 aa)
KANSL3KAT8 regulatory NSL complex subunit 3. (904 aa)
P3H3Prolyl 3-hydroxylase 3. (694 aa)
PRDM5Zinc finger protein. (599 aa)
KMT5BLysine methyltransferase 5B. (883 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (487 aa)
CHD5Chromodomain helicase DNA binding protein 5. (1928 aa)
KAT2BLysine acetyltransferase 2B. (755 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (22%) [HD]