Your Input: | |||||
RUBCNL | Rubicon like autophagy enhancer. (691 aa) | ||||
SPHK2 | Sphingosine kinase 2. (615 aa) | ||||
HTR2A | 5-hydroxytryptamine receptor 2A. (470 aa) | ||||
AMBRA1 | WD_REPEATS_REGION domain-containing protein. (766 aa) | ||||
LACTB | Lactamase beta. (433 aa) | ||||
FGFR4 | Fibroblast growth factor receptor. (801 aa) | ||||
FITM2 | Fat storage inducing transmembrane protein 2. (262 aa) | ||||
FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) | ||||
KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (545 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa) | ||||
ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) | ||||
MTMR9 | Myotubularin related protein 9. (545 aa) | ||||
SLC45A3 | Solute carrier family 45 member 3. (552 aa) | ||||
DKKL1 | Dickkopf like acrosomal protein 1. (233 aa) | ||||
FMO2 | Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa) | ||||
ABHD6 | Abhydrolase domain containing 6. (338 aa) | ||||
PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa) | ||||
IDH1 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (420 aa) | ||||
NR4A3 | Nuclear receptor subfamily 4 group A member 3. (626 aa) | ||||
CD81 | Tetraspanin. (214 aa) | ||||
RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (342 aa) | ||||
RUBCN | Rubicon autophagy regulator. (957 aa) | ||||
ASXL3 | ASXL transcriptional regulator 3. (2181 aa) | ||||
VAV3 | Vav guanine nucleotide exchange factor 3. (847 aa) | ||||
ATG14 | Autophagy related 14. (492 aa) | ||||
LPGAT1 | Lysophosphatidylglycerol acyltransferase 1. (385 aa) | ||||
ABCG4 | ATP binding cassette subfamily G member 4. (645 aa) | ||||
PPARD | Peroxisome proliferator activated receptor delta. (441 aa) | ||||
CD74 | CD74 molecule. (280 aa) | ||||
H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (796 aa) | ||||
PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) | ||||
ELOVL5 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (300 aa) | ||||
SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (361 aa) | ||||
ACADVL | Acyl-CoA dehydrogenase very long chain. (655 aa) | ||||
PRMT3 | Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (449 aa) | ||||
ERLIN1 | ER lipid raft associated 1. (350 aa) | ||||
RORC | RAR related orphan receptor C. (517 aa) | ||||
PLIN5 | Perilipin; Belongs to the perilipin family. (371 aa) | ||||
GPS2 | G protein pathway suppressor 2. (327 aa) | ||||
PHB2 | Prohibitin. (300 aa) | ||||
HCAR1 | Hydroxycarboxylic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (299 aa) | ||||
IGFBP7 | Insulin like growth factor binding protein 7. (283 aa) | ||||
CCN1 | Cellular communication network factor 1. (383 aa) | ||||
FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
FMO1 | Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa) | ||||
PDK3 | Protein-serine/threonine kinase. (415 aa) | ||||
CCL21 | SCY domain-containing protein. (110 aa) | ||||
PROX1 | Prospero homeobox 1. (737 aa) | ||||
TM6SF2 | Transmembrane 6 superfamily member 2. (377 aa) | ||||
SPHK1 | Sphingosine kinase 1. (386 aa) | ||||
SREBF1 | Sterol regulatory element binding transcription factor 1. (1087 aa) | ||||
THRSP | Thyroid hormone responsive. (150 aa) | ||||
STOML2 | Stomatin like 2. (357 aa) | ||||
FGFR3 | Fibroblast growth factor receptor. (804 aa) | ||||
MFSD2A | Major facilitator superfamily domain containing 2A. (531 aa) | ||||
G3TTA5_LOXAF | Uncharacterized protein. (152 aa) | ||||
SCAP | SREBF chaperone. (1285 aa) | ||||
G3TUG9_LOXAF | Flavin-containing monooxygenase. (178 aa) | ||||
PRKCD | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (701 aa) | ||||
THRA | Thyroid hormone receptor alpha. (487 aa) | ||||
WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) | ||||
APOC2 | Apolipoprotein C2. (101 aa) | ||||
G3TWY0_LOXAF | Uncharacterized protein. (88 aa) | ||||
DGKZ | Diacylglycerol kinase. (1118 aa) | ||||
DNAJC19 | Uncharacterized protein. (129 aa) | ||||
TEK | TEK receptor tyrosine kinase. (1125 aa) | ||||
CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (185 aa) | ||||
ETFBKMT | Electron transfer flavoprotein subunit beta lysine methyltransferase. (266 aa) | ||||
CLCN2 | Chloride channel protein. (902 aa) | ||||
G3TZS1_LOXAF | PlsC domain-containing protein. (488 aa) | ||||
G3TZT1_LOXAF | Uncharacterized protein. (294 aa) | ||||
ARMC5 | Armadillo repeat containing 5. (925 aa) | ||||
APOBEC1 | Apolipoprotein B mRNA editing enzyme catalytic subunit 1. (223 aa) | ||||
PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) | ||||
PLA2G6 | Phospholipase A2 group VI. (808 aa) | ||||
FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) | ||||
EPHX2 | Epoxide hydrolase 2. (558 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1011 aa) | ||||
SEC14L3 | SEC14 like lipid binding 3. (400 aa) | ||||
DAGLB | Lipase_3 domain-containing protein. (354 aa) | ||||
PDK1 | Protein-serine/threonine kinase. (389 aa) | ||||
GIP | Gastric inhibitory polypeptide. (144 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) | ||||
DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (282 aa) | ||||
DNAJC15 | DnaJ heat shock protein family (Hsp40) member C15. (146 aa) | ||||
SCP2 | Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (515 aa) | ||||
DGKQ | Diacylglycerol kinase. (850 aa) | ||||
IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (262 aa) | ||||
DISP3 | Dispatched RND transporter family member 3. (1389 aa) | ||||
ADIPOQ | Adiponectin, C1Q and collagen domain containing. (245 aa) | ||||
ABCD2 | ATP binding cassette subfamily D member 2. (742 aa) | ||||
LPCAT3 | Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa) | ||||
MTMR4 | Myotubularin related protein 4. (1198 aa) | ||||
INSIG2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) | ||||
SORBS1 | Sorbin and SH3 domain containing 1. (1291 aa) | ||||
PIK3IP1 | Phosphoinositide-3-kinase interacting protein 1. (262 aa) | ||||
ZBTB20 | Zinc finger and BTB domain containing 20. (743 aa) | ||||
CIDEA | Cell death inducing DFFA like effector a. (217 aa) | ||||
ANGPTL3 | Angiopoietin like 3. (454 aa) | ||||
SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (312 aa) | ||||
STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) | ||||
CCDC3 | Coiled-coil domain containing 3. (256 aa) | ||||
ACSL3 | Acyl-CoA synthetase long chain family member 3. (720 aa) | ||||
ORMDL3 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) | ||||
CRTC3 | CREB regulated transcription coactivator 3. (547 aa) | ||||
SIK1 | Uncharacterized protein. (795 aa) | ||||
PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (405 aa) | ||||
CTDNEP1 | CTD nuclear envelope phosphatase 1. (245 aa) | ||||
CGA | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (121 aa) | ||||
BSCL2 | BSCL2 lipid droplet biogenesis associated, seipin. (381 aa) | ||||
MID1IP1 | MID1 interacting protein 1. (183 aa) | ||||
PSAP | Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (527 aa) | ||||
RORA | RAR related orphan receptor A. (467 aa) | ||||
LDLR | Low density lipoprotein receptor. (858 aa) | ||||
DHCR7 | 7-dehydrocholesterol reductase. (475 aa) | ||||
DDX20 | DEAD-box helicase 20; Belongs to the DEAD box helicase family. (800 aa) | ||||
STARD4 | StAR related lipid transfer domain containing 4. (209 aa) | ||||
SEC14L5 | SEC14 like lipid binding 5. (633 aa) | ||||
BBS4 | Bardet-Biedl syndrome 4. (506 aa) | ||||
TRIB3 | Tribbles pseudokinase 3. (358 aa) | ||||
CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (503 aa) | ||||
ABCB11 | ATP binding cassette subfamily B member 11. (1324 aa) | ||||
LAMTOR1 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa) | ||||
WDTC1 | WD and tetratricopeptide repeats 1. (677 aa) | ||||
CREBL2 | cAMP responsive element binding protein like 2. (170 aa) | ||||
SF1 | Splicing factor 1. (645 aa) | ||||
MACROH2A1 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) | ||||
ORMDL1 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) | ||||
LYN | Tyrosine-protein kinase. (512 aa) | ||||
DAB2IP | DAB2 interacting protein. (1189 aa) | ||||
LPIN1 | Lipin 1. (929 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (96 aa) | ||||
ABHD5 | Abhydrolase domain containing 5. (345 aa) | ||||
MLYCD | Malonyl-CoA decarboxylase. (497 aa) | ||||
MTMR2 | Myotubularin related protein 2. (617 aa) | ||||
NR1H2 | Nuclear receptor subfamily 1 group H member 2. (454 aa) | ||||
ASAH1 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (394 aa) | ||||
G3T2K6_LOXAF | Myotubularin phosphatase domain-containing protein. (520 aa) | ||||
SORL1 | Sortilin related receptor 1. (2220 aa) | ||||
LOC100660588 | Dimethylaniline monooxygenase [N-oxide-forming]. (539 aa) | ||||
NCOA2 | Nuclear receptor coactivator. (1461 aa) | ||||
PIBF1 | Progesterone immunomodulatory binding factor 1. (730 aa) | ||||
PPARA | Peroxisome proliferator activated receptor alpha. (468 aa) | ||||
TTC39B | Tetratricopeptide repeat domain 39B. (556 aa) | ||||
STAT5B | Signal transducer and activator of transcription. (787 aa) | ||||
STAT5A | Signal transducer and activator of transcription. (794 aa) | ||||
LONP2 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (853 aa) | ||||
NOD2 | Nucleotide binding oligomerization domain containing 2. (1020 aa) | ||||
APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (662 aa) | ||||
APOE | Apolipoprotein E. (314 aa) | ||||
DAB2 | DAB adaptor protein 2. (768 aa) | ||||
FMO5 | Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa) | ||||
NR1H4 | Nuclear receptor subfamily 1 group H member 4. (486 aa) | ||||
ABCG1 | ATP binding cassette subfamily G member 1. (666 aa) | ||||
ANXA1 | Annexin. (348 aa) | ||||
APOB | Apolipoprotein B. (3100 aa) | ||||
BCL11B | BAF chromatin remodeling complex subunit BCL11B. (883 aa) | ||||
NR1H3 | Nuclear receptor subfamily 1 group H member 3. (447 aa) | ||||
PCK1 | Phosphoenolpyruvate carboxykinase 1. (624 aa) | ||||
SIRT1 | Sirtuin 1. (605 aa) | ||||
SNAI2 | Snail family transcriptional repressor 2. (268 aa) | ||||
ADGRF5 | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1271 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (973 aa) | ||||
PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1359 aa) | ||||
DHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa) | ||||
APOA5 | Apolipoprotein A5. (371 aa) | ||||
F2 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (619 aa) | ||||
SIRT3 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (257 aa) | ||||
G3U4G1_LOXAF | Ig-like domain-containing protein. (504 aa) | ||||
EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (548 aa) | ||||
SERPINA12 | Serpin family A member 12; Belongs to the serpin family. (413 aa) | ||||
PDE3B | Phosphodiesterase. (1112 aa) | ||||
SIRT6 | Sirtuin 6. (336 aa) | ||||
GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa) | ||||
VAV2 | Vav guanine nucleotide exchange factor 2. (866 aa) | ||||
HTR2B | 5-hydroxytryptamine receptor 2B. (477 aa) | ||||
LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) | ||||
CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa) | ||||
FMC1 | Formation of mitochondrial complex V assembly factor 1 homolog. (113 aa) | ||||
AVIL | Advillin. (822 aa) | ||||
PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1091 aa) | ||||
ERFE | Erythroferrone. (331 aa) | ||||
ZFP69B | ZFP69 zinc finger protein B. (417 aa) | ||||
LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (631 aa) | ||||
PDK4 | Protein-serine/threonine kinase. (412 aa) | ||||
GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (840 aa) | ||||
ERLIN2 | ER lipid raft associated 2. (339 aa) | ||||
LPCAT1 | Uncharacterized protein. (477 aa) | ||||
MTMR3 | Myotubularin related protein 3. (1204 aa) | ||||
ARV1 | ARV1 homolog, fatty acid homeostasis modulator. (271 aa) | ||||
PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (191 aa) | ||||
ANKRD26 | Ankyrin repeat domain 26. (1604 aa) | ||||
EPHA8 | EPH receptor A8. (974 aa) | ||||
APOD | Apolipoprotein D. (190 aa) | ||||
GOLM1 | Golgi membrane protein 1. (364 aa) | ||||
EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) | ||||
ACER1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (233 aa) | ||||
PLA2G3 | Phospholipase A2 group III. (494 aa) | ||||
CNEP1R1 | CTD nuclear envelope phosphatase 1 regulatory subunit 1. (125 aa) | ||||
CREB1 | cAMP responsive element binding protein 1. (341 aa) | ||||
SAMD8 | Sterile alpha motif domain containing 8. (467 aa) | ||||
BMP6 | Bone morphogenetic protein 6. (298 aa) | ||||
BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1854 aa) | ||||
FMO4 | Dimethylaniline monooxygenase [N-oxide-forming]. (555 aa) | ||||
SREBF2 | Sterol regulatory element binding transcription factor 2. (1109 aa) | ||||
MBOAT7 | Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family. (471 aa) | ||||
MTMR1 | Myotubularin related protein 1. (620 aa) | ||||
CERS2 | Ceramide synthase 2. (389 aa) | ||||
PIP4K2C | Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (422 aa) | ||||
ENPP7 | Ectonucleotide pyrophosphatase/phosphodiesterase 7. (401 aa) | ||||
ORMDL2 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) | ||||
SNAI1 | Snail family transcriptional repressor 1. (264 aa) | ||||
TTC39A | Tetratricopeptide repeat domain 39A. (585 aa) | ||||
NCOR1 | Nuclear receptor corepressor 1. (2457 aa) | ||||
MLXIPL | MLX interacting protein like. (860 aa) | ||||
PDK2 | Protein-serine/threonine kinase. (362 aa) | ||||
FABP5 | Fatty acid binding protein 5. (134 aa) | ||||
G3UIG1_LOXAF | J domain-containing protein. (116 aa) | ||||
NR1D2 | Nuclear receptor subfamily 1 group D member 2. (576 aa) | ||||
PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (424 aa) | ||||
ABCD1 | ATP binding cassette subfamily D member 1. (739 aa) | ||||
G3UGT0_LOXAF | Uncharacterized protein. (152 aa) | ||||
TYSND1 | Trypsin domain containing 1. (455 aa) | ||||
STUB1 | STIP1 homology and U-box containing protein 1. (303 aa) | ||||
FGR | Tyrosine-protein kinase. (527 aa) | ||||
G3UEB2_LOXAF | Uncharacterized protein. (544 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1161 aa) | ||||
CCL19 | C-C motif chemokine. (103 aa) | ||||
G3UC04_LOXAF | Uncharacterized protein. (327 aa) | ||||
WASHC1 | WASH complex subunit 1. (474 aa) | ||||
INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (263 aa) | ||||
MALRD1 | Uncharacterized protein. (351 aa) | ||||
G3UA36_LOXAF | Uncharacterized protein. (403 aa) | ||||
REST | RE1 silencing transcription factor. (1067 aa) | ||||
NR0B1 | Nuclear receptor subfamily 0 group B member 1. (471 aa) | ||||
PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) | ||||
ANGPTL8 | Angiopoietin like 8. (198 aa) | ||||
NR1D1 | Nuclear receptor subfamily 1 group D member 1. (611 aa) | ||||
RARRES2 | Retinoic acid receptor responder 2. (163 aa) |