node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CARD11 | MALT1 | ENSLAFP00000003881 | ENSLAFP00000015402 | Caspase recruitment domain family member 11. | MALT1 paracaspase. | 0.989 |
CARD11 | MAP3K7 | ENSLAFP00000003881 | ENSLAFP00000015626 | Caspase recruitment domain family member 11. | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.701 |
CARD11 | PRKCQ | ENSLAFP00000003881 | ENSLAFP00000001356 | Caspase recruitment domain family member 11. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.992 |
CARD11 | RIPK2 | ENSLAFP00000003881 | ENSLAFP00000022310 | Caspase recruitment domain family member 11. | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. | 0.477 |
CARD11 | TRAF6 | ENSLAFP00000003881 | ENSLAFP00000019862 | Caspase recruitment domain family member 11. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.759 |
CD83 | IL1B | ENSLAFP00000015061 | ENSLAFP00000003388 | CD83 molecule. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.412 |
IL1A | IL1B | ENSLAFP00000001051 | ENSLAFP00000003388 | Interleukin-1; Belongs to the IL-1 family. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.999 |
IL1A | TRAF6 | ENSLAFP00000001051 | ENSLAFP00000019862 | Interleukin-1; Belongs to the IL-1 family. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.711 |
IL1B | CD83 | ENSLAFP00000003388 | ENSLAFP00000015061 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | CD83 molecule. | 0.412 |
IL1B | IL1A | ENSLAFP00000003388 | ENSLAFP00000001051 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-1; Belongs to the IL-1 family. | 0.999 |
IL1B | MALT1 | ENSLAFP00000003388 | ENSLAFP00000015402 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | MALT1 paracaspase. | 0.459 |
IL1B | PTPRC | ENSLAFP00000003388 | ENSLAFP00000001762 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Protein tyrosine phosphatase receptor type C. | 0.434 |
IL1B | TRAF6 | ENSLAFP00000003388 | ENSLAFP00000019862 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.787 |
MALT1 | CARD11 | ENSLAFP00000015402 | ENSLAFP00000003881 | MALT1 paracaspase. | Caspase recruitment domain family member 11. | 0.989 |
MALT1 | IL1B | ENSLAFP00000015402 | ENSLAFP00000003388 | MALT1 paracaspase. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.459 |
MALT1 | MAP3K7 | ENSLAFP00000015402 | ENSLAFP00000015626 | MALT1 paracaspase. | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.630 |
MALT1 | PRKCQ | ENSLAFP00000015402 | ENSLAFP00000001356 | MALT1 paracaspase. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.623 |
MALT1 | TRAF6 | ENSLAFP00000015402 | ENSLAFP00000019862 | MALT1 paracaspase. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.938 |
MAP3K7 | CARD11 | ENSLAFP00000015626 | ENSLAFP00000003881 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | Caspase recruitment domain family member 11. | 0.701 |
MAP3K7 | MALT1 | ENSLAFP00000015626 | ENSLAFP00000015402 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | MALT1 paracaspase. | 0.630 |