STRINGSTRING
CARTPT CARTPT NRIP1 NRIP1 MAGED1 MAGED1 KDM2A KDM2A NAMPT NAMPT CRY2 CRY2 G3UJA9_LOXAF G3UJA9_LOXAF MTA1 MTA1 RBM4B RBM4B ARNTL2 ARNTL2 PML PML CIART CIART NGFR NGFR PRMT5 PRMT5 HDAC1 HDAC1 BHLHE40 BHLHE40 MYBBP1A MYBBP1A PPP1CB PPP1CB HDAC2 HDAC2 MC3R MC3R USP2 USP2 DRD2 DRD2 CSNK1D CSNK1D ID2 ID2 HDAC3 HDAC3 RELB RELB MYCBP2 MYCBP2 OGT OGT NCOA2 NCOA2 SIRT1 SIRT1 CLOCK CLOCK KDM5A KDM5A CAVIN3 CAVIN3 PER2 PER2 ATF4 ATF4 PER1 PER1 PPARGC1A PPARGC1A PPARA PPARA ID4 ID4 HUWE1 HUWE1 AHR AHR PPP1CC PPP1CC NR0B2 NR0B2 NOCT NOCT ZFHX3 ZFHX3 RAI1 RAI1 KDM8 KDM8 RORC RORC PPP1CA PPP1CA LOC100666300 LOC100666300 ID1 ID1 TOP1 TOP1 HNRNPU HNRNPU RBM4 RBM4 ARNTL ARNTL ID3 ID3 CRY1 CRY1 NUDT12 NUDT12 EGR1 EGR1 SIRT6 SIRT6 NPAS2 NPAS2 NR1D1 NR1D1 G3UCX2_LOXAF G3UCX2_LOXAF RORA RORA PER3 PER3 LGR4 LGR4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CARTPTCART prepropeptide. (128 aa)
NRIP1Nuclear receptor interacting protein 1. (1159 aa)
MAGED1MAGE family member D1. (757 aa)
KDM2ALysine demethylase 2A. (1161 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (497 aa)
CRY2Cryptochrome circadian regulator 2. (592 aa)
G3UJA9_LOXAFUncharacterized protein. (400 aa)
MTA1Metastasis associated 1. (660 aa)
RBM4BRNA binding motif protein 4B. (359 aa)
ARNTL2Aryl hydrocarbon receptor nuclear translocator like 2. (482 aa)
PMLPromyelocytic leukemia. (861 aa)
CIARTCircadian associated repressor of transcription. (381 aa)
NGFRNerve growth factor receptor. (414 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
BHLHE40Basic helix-loop-helix family member e40. (412 aa)
MYBBP1AMYB binding protein 1a. (1315 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (487 aa)
MC3RMelanocortin 3 receptor. (323 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (576 aa)
DRD2Dopamine receptor D2. (447 aa)
CSNK1DCasein kinase 1 delta. (416 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
HDAC3Hist_deacetyl domain-containing protein. (349 aa)
RELBRELB proto-oncogene, NF-kB subunit. (547 aa)
MYCBP2MYC binding protein 2. (4717 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
NCOA2Nuclear receptor coactivator. (1461 aa)
SIRT1Sirtuin 1. (605 aa)
CLOCKClock circadian regulator. (849 aa)
KDM5ALysine demethylase 5A. (1582 aa)
CAVIN3Caveolae associated protein 3. (261 aa)
PER2Period circadian regulator 2. (1252 aa)
ATF4Activating transcription factor 4. (379 aa)
PER1Period circadian regulator 1. (1287 aa)
PPARGC1APPARG coactivator 1 alpha. (796 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (161 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4372 aa)
AHRUncharacterized protein. (801 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (260 aa)
NOCTNocturnin. (368 aa)
ZFHX3Zinc finger homeobox 3. (3700 aa)
RAI1Retinoic acid induced 1. (1821 aa)
KDM8Lysine demethylase 8. (416 aa)
RORCRAR related orphan receptor C. (517 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
LOC100666300Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (770 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (824 aa)
RBM4RNA binding motif protein 4. (365 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (620 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
CRY1Cryptochrome circadian regulator 1. (606 aa)
NUDT12Nudix hydrolase 12. (463 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (548 aa)
SIRT6Sirtuin 6. (336 aa)
NPAS2Neuronal PAS domain protein 2. (810 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (611 aa)
G3UCX2_LOXAFBHLH domain-containing protein. (364 aa)
RORARAR related orphan receptor A. (467 aa)
PER3Period circadian regulator 3. (1018 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (907 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.