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TTYH1 TTYH1 GABRB1 GABRB1 CLCN1 CLCN1 GABRA3 GABRA3 OSTM1 OSTM1 TTYH2 TTYH2 BEST3 BEST3 CLIC6 CLIC6 CLIC5 CLIC5 GABRB3 GABRB3 GABRA2 GABRA2 BEST4 BEST4 GABRE GABRE G3SSR0_LOXAF G3SSR0_LOXAF CLCN7 CLCN7 GLRA2 GLRA2 GABRG1 GABRG1 CLCC1 CLCC1 BEST1 BEST1 CLCN2 CLCN2 GABRG2 GABRG2 ANO6 ANO6 GABRA5 GABRA5 CLIC1 CLIC1 CLIC3 CLIC3 GLRA1 GLRA1 GABRA4 GABRA4 TTYH3 TTYH3 GABRB2 GABRB2 PACC1 PACC1 CLIC4 CLIC4 GABRA6 GABRA6 GABRP GABRP GABRD GABRD LOC100654229 LOC100654229 CLIC2 CLIC2 CFTR CFTR GABRR1 GABRR1 GABRR2 GABRR2 GABRA1 GABRA1 GABRG3 GABRG3 GLRA3 GLRA3 GLRB GLRB CLDN17 CLDN17 BEST2 BEST2 GLRA4 GLRA4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TTYH1Protein tweety homolog; Probable chloride channel. (451 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
CLCN1Chloride voltage-gated channel 1. (728 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (498 aa)
OSTM1Osteoclastogenesis associated transmembrane protein 1. (331 aa)
TTYH2Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (530 aa)
BEST3Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (676 aa)
CLIC6Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (229 aa)
CLIC5Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (252 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (396 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
BEST4Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (379 aa)
GABREGamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (484 aa)
G3SSR0_LOXAFUncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (437 aa)
CLCN7Chloride channel protein. (810 aa)
GLRA2Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
CLCC1Chloride channel CLIC like 1. (528 aa)
BEST1Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (510 aa)
CLCN2Chloride channel protein. (902 aa)
GABRG2Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (473 aa)
ANO6Anoctamin. (821 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
CLIC1Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (251 aa)
CLIC3Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (237 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (555 aa)
TTYH3Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (523 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
PACC1Proton activated chloride channel 1. (338 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (252 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
GABRPGamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (449 aa)
LOC100654229Chloride channel protein. (691 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (245 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1479 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (479 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (491 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (275 aa)
GLRA3Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
GLRBGlycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)
CLDN17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
BEST2Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (478 aa)
GLRA4Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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