STRINGSTRING
CD4 CD4 G3ULQ3_LOXAF G3ULQ3_LOXAF JAG2 JAG2 APBB1IP APBB1IP G3UKJ3_LOXAF G3UKJ3_LOXAF RAG1 RAG1 TCIRG1 TCIRG1 G3UK14_LOXAF G3UK14_LOXAF IFNB1 IFNB1 G3UJ64_LOXAF G3UJ64_LOXAF G3UJ15_LOXAF G3UJ15_LOXAF G3UJ00_LOXAF G3UJ00_LOXAF CCR6 CCR6 NKG7 NKG7 G3UIA1_LOXAF G3UIA1_LOXAF G3UI57_LOXAF G3UI57_LOXAF G3UI37_LOXAF G3UI37_LOXAF G3UHY3_LOXAF G3UHY3_LOXAF G3UHE5_LOXAF G3UHE5_LOXAF G3UHA8_LOXAF G3UHA8_LOXAF CHD7 CHD7 G3UDE4_LOXAF G3UDE4_LOXAF STAT3 STAT3 CCL19 CCL19 G3UCD2_LOXAF G3UCD2_LOXAF ITK ITK G3UAZ0_LOXAF G3UAZ0_LOXAF G3UA54_LOXAF G3UA54_LOXAF CD84 CD84 SOX13 SOX13 PSEN1 PSEN1 LIG4 LIG4 FZD8 FZD8 G3U6U6_LOXAF G3U6U6_LOXAF G3U6D1_LOXAF G3U6D1_LOXAF G3U5X1_LOXAF G3U5X1_LOXAF MSN MSN EGR1 EGR1 G3U502_LOXAF G3U502_LOXAF ADA ADA GPR18 GPR18 RIPK2 RIPK2 WAS WAS BRAF BRAF FKBP1A FKBP1A G3U0Z2_LOXAF G3U0Z2_LOXAF G3U0L7_LOXAF G3U0L7_LOXAF ARMC5 ARMC5 CORO1A CORO1A GPR183 GPR183 G3TZG9_LOXAF G3TZG9_LOXAF EIF2AK4 EIF2AK4 CEBPB CEBPB G3TYF2_LOXAF G3TYF2_LOXAF NCAPH2 NCAPH2 CTPS1 CTPS1 MR1 MR1 WNT4 WNT4 DPP4 DPP4 FZD5 FZD5 PTPN6 PTPN6 TBX21 TBX21 JMJD6 JMJD6 LOC100654941 LOC100654941 STOML2 STOML2 G3TS29_LOXAF G3TS29_LOXAF G3TS21_LOXAF G3TS21_LOXAF EBI3 EBI3 CRTAM CRTAM PAX1 PAX1 KIT KIT CLEC4G CLEC4G CCL21 CCL21 G3TPG3_LOXAF G3TPG3_LOXAF P2RX7 P2RX7 CCR7 CCR7 G3TNN3_LOXAF G3TNN3_LOXAF SLAMF9 SLAMF9 CLEC4E CLEC4E RAB29 RAB29 LY9 LY9 G3TLR0_LOXAF G3TLR0_LOXAF RORC RORC PSMB11 PSMB11 TNFSF8 TNFSF8 VAV1 VAV1 CDK6 CDK6 ZBTB1 ZBTB1 LFNG LFNG MALT1 MALT1 CTNNB1 CTNNB1 IL6R IL6R CD83 CD83 PTGER4 PTGER4 CD28 CD28 SLA2 SLA2 CD74 CD74 RSAD2 RSAD2 ATG5 ATG5 TCF7 TCF7 CRACR2A CRACR2A G3THL4_LOXAF G3THL4_LOXAF G3THF4_LOXAF G3THF4_LOXAF RAG2 RAG2 G3TH21_LOXAF G3TH21_LOXAF LEF1 LEF1 G3TGZ0_LOXAF G3TGZ0_LOXAF IL12B IL12B MTOR MTOR IL6 IL6 CD276 CD276 IL23A IL23A DLL4 DLL4 NKX2-3 NKX2-3 FOXN1 FOXN1 LRRC1 LRRC1 CBLB CBLB CD2 CD2 TESPA1 TESPA1 G3TBU1_LOXAF G3TBU1_LOXAF ITGAL ITGAL NCK1 NCK1 SP3 SP3 IL7R IL7R TNFSF13B TNFSF13B WDFY4 WDFY4 BCL6 BCL6 GPR89A GPR89A CYP26B1 CYP26B1 RIPK3 RIPK3 SYK SYK PTPN2 PTPN2 ITCH ITCH STK11 STK11 ITPKB ITPKB G3T7D7_LOXAF G3T7D7_LOXAF PKNOX1 PKNOX1 BATF BATF CD3D CD3D CD3E CD3E NCSTN NCSTN TMEM98 TMEM98 LEP LEP DOCK8 DOCK8 PELI1 PELI1 SRF SRF LOC100655922 LOC100655922 LMBR1L LMBR1L EFNB1 EFNB1 IL4 IL4 LCP1 LCP1 BCL11B BCL11B ANXA1 ANXA1 SH2D2A SH2D2A GLI3 GLI3 IL15 IL15 AIRE AIRE AZI2 AZI2 JAML JAML TSC1 TSC1 RELB RELB TOX TOX TREML2 TREML2 IL18R1 IL18R1 TGFB1 TGFB1 IRF1 IRF1 CCR9 CCR9 TP53 TP53 NLRC3 NLRC3 IL2RG IL2RG CXADR CXADR THEMIS THEMIS CRIP3 CRIP3 ATF2 ATF2 GPAM GPAM IL21 IL21 STAT6 STAT6 ENTPD7 ENTPD7 SASH3 SASH3 FKBP1B FKBP1B SLAMF7 SLAMF7 CD48 CD48 TRAF3IP2 TRAF3IP2 IFNK IFNK CARD11 CARD11 IL2 IL2 RC3H1 RC3H1 WNT1 WNT1 WNT10B WNT10B EOMES EOMES CD8A CD8A RABL3 RABL3 TNFRSF4 TNFRSF4 LEPR LEPR RC3H2 RC3H2 FOXP3 FOXP3 SEMA4A SEMA4A GATA3 GATA3 PATZ1 PATZ1 PTPRC PTPRC PRKCQ PRKCQ SLC11A1 SLC11A1 RASGRP1 RASGRP1 HLX HLX FGL2 FGL2 CLEC4D CLEC4D IL20RB IL20RB RORA RORA BCL2 BCL2 IKZF3 IKZF3 RHOH RHOH HSPD1 HSPD1 FOXP1 FOXP1 ZAP70 ZAP70 G3ULT4_LOXAF G3ULT4_LOXAF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CD4CD4 molecule. (471 aa)
G3ULQ3_LOXAFTyrosine-protein phosphatase non-receptor type. (369 aa)
JAG2Uncharacterized protein. (571 aa)
APBB1IPUncharacterized protein. (305 aa)
G3UKJ3_LOXAFUncharacterized protein. (191 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (813 aa)
G3UK14_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (365 aa)
IFNB1Interferon beta 1. (187 aa)
G3UJ64_LOXAFUncharacterized protein. (1460 aa)
G3UJ15_LOXAFETS domain-containing protein. (442 aa)
G3UJ00_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (360 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (363 aa)
NKG7Natural killer cell granule protein 7. (165 aa)
G3UIA1_LOXAFEph LBD domain-containing protein. (351 aa)
G3UI57_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (360 aa)
G3UI37_LOXAFUncharacterized protein. (453 aa)
G3UHY3_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (288 aa)
G3UHE5_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa)
G3UHA8_LOXAFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (430 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2997 aa)
G3UDE4_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (362 aa)
STAT3Signal transducer and activator of transcription. (772 aa)
CCL19C-C motif chemokine. (103 aa)
G3UCD2_LOXAFUncharacterized protein. (195 aa)
ITKTyrosine-protein kinase. (605 aa)
G3UAZ0_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (364 aa)
G3UA54_LOXAFC-type lectin domain-containing protein. (160 aa)
CD84CD84 molecule. (335 aa)
SOX13SRY-box transcription factor 13. (700 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (440 aa)
LIG4DNA ligase. (913 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (503 aa)
G3U6U6_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa)
G3U6D1_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (364 aa)
G3U5X1_LOXAFKinase; Belongs to the inositol phosphokinase (IPK) family. (305 aa)
MSNMoesin. (578 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (548 aa)
G3U502_LOXAFIg_4 domain-containing protein. (156 aa)
ADAAdenosine deaminase. (351 aa)
GPR18G protein-coupled receptor 18. (331 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa)
WASWASP actin nucleation promoting factor. (502 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (740 aa)
FKBP1APeptidylprolyl isomerase. (137 aa)
G3U0Z2_LOXAFUncharacterized protein. (194 aa)
G3U0L7_LOXAFUncharacterized protein. (423 aa)
ARMC5Armadillo repeat containing 5. (925 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (459 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa)
G3TZG9_LOXAFUncharacterized protein. (171 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1594 aa)
CEBPBBZIP domain-containing protein. (124 aa)
G3TYF2_LOXAFUncharacterized protein. (189 aa)
NCAPH2Non-SMC condensin II complex subunit H2. (606 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (592 aa)
MR1Major histocompatibility complex, class I-related; Belongs to the MHC class I family. (320 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (761 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
TBX21T-box transcription factor 21. (532 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (367 aa)
LOC100654941Uncharacterized protein. (472 aa)
STOML2Stomatin like 2. (357 aa)
G3TS29_LOXAFUncharacterized protein. (183 aa)
G3TS21_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (363 aa)
EBI3Epstein-Barr virus induced 3. (229 aa)
CRTAMCytotoxic and regulatory T cell molecule. (369 aa)
PAX1Paired box 1. (453 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa)
CLEC4GC-type lectin domain family 4 member G. (294 aa)
CCL21SCY domain-containing protein. (110 aa)
G3TPG3_LOXAFC-type lectin domain-containing protein. (135 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (599 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
G3TNN3_LOXAFUncharacterized protein. (178 aa)
SLAMF9SLAM family member 9. (288 aa)
CLEC4EC-type lectin domain family 4 member E. (216 aa)
RAB29RAB29, member RAS oncogene family. (204 aa)
LY9Lymphocyte antigen 9. (643 aa)
G3TLR0_LOXAFIGc1 domain-containing protein. (358 aa)
RORCRAR related orphan receptor C. (517 aa)
PSMB11Proteasome subunit beta. (253 aa)
TNFSF8Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family. (235 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
ZBTB1Zinc finger and BTB domain containing 1. (714 aa)
LFNGLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (262 aa)
MALT1MALT1 paracaspase. (834 aa)
CTNNB1Catenin beta 1. (780 aa)
IL6RInterleukin 6 receptor. (444 aa)
CD83CD83 molecule. (206 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (492 aa)
CD28CD28 molecule. (203 aa)
SLA2Src like adaptor 2. (261 aa)
CD74CD74 molecule. (280 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (360 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (277 aa)
TCF7Transcription factor 7. (476 aa)
CRACR2AEF-hand domain-containing protein. (314 aa)
G3THL4_LOXAFUncharacterized protein. (146 aa)
G3THF4_LOXAFCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (593 aa)
RAG2Recombination activating 2. (527 aa)
G3TH21_LOXAFRas-associating domain-containing protein. (262 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
G3TGZ0_LOXAFUncharacterized protein. (202 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (331 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa)
IL6Interleukin 6. (212 aa)
CD276CD276 molecule. (508 aa)
IL23AInterleukin 23 subunit alpha. (191 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
NKX2-3NK2 homeobox 3. (371 aa)
FOXN1Forkhead box N1. (650 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
CBLBCbl proto-oncogene B. (983 aa)
CD2CD2 molecule. (343 aa)
TESPA1Thymocyte expressed, positive selection associated 1. (469 aa)
G3TBU1_LOXAFUncharacterized protein. (89 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1162 aa)
NCK1Cytoplasmic protein. (377 aa)
SP3Sp3 transcription factor. (688 aa)
IL7RInterleukin 7 receptor. (459 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (322 aa)
WDFY4Uncharacterized protein. (805 aa)
BCL6BCL6 transcription repressor. (708 aa)
GPR89AUncharacterized protein. (455 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
RIPK3Uncharacterized protein. (50 aa)
SYKTyrosine-protein kinase. (629 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (409 aa)
ITCHE3 ubiquitin-protein ligase. (865 aa)
STK11Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (439 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (620 aa)
G3T7D7_LOXAFUncharacterized protein. (196 aa)
PKNOX1PBX/knotted 1 homeobox 1. (436 aa)
BATFBasic leucine zipper ATF-like transcription factor. (122 aa)
CD3DIg_4 domain-containing protein. (172 aa)
CD3ECD3e molecule. (189 aa)
NCSTNNicastrin. (451 aa)
TMEM98Transmembrane protein 98. (226 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2101 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
SRFSerum response factor. (391 aa)
LOC100655922C-type lectin domain-containing protein. (235 aa)
LMBR1LLimb development membrane protein 1 like; Belongs to the LIMR family. (489 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (297 aa)
IL4Uncharacterized protein. (135 aa)
LCP1Lymphocyte cytosolic protein 1. (627 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (883 aa)
ANXA1Annexin. (348 aa)
SH2D2ASH2 domain containing 2A. (386 aa)
GLI3GLI family zinc finger 3. (1586 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
AIREAutoimmune regulator. (557 aa)
AZI2Uncharacterized protein. (215 aa)
JAMLIg-like domain-containing protein. (178 aa)
TSC1TSC complex subunit 1. (869 aa)
RELBRELB proto-oncogene, NF-kB subunit. (547 aa)
TOXThymocyte selection associated high mobility group box. (526 aa)
TREML2Ig-like domain-containing protein. (308 aa)
IL18R1Interleukin 18 receptor 1. (539 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
IRF1Interferon regulatory factor. (326 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (371 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa)
NLRC3NLR family CARD domain containing 3. (1037 aa)
IL2RGFibronectin type-III domain-containing protein. (368 aa)
CXADRUncharacterized protein. (365 aa)
THEMISThymocyte selection associated. (516 aa)
CRIP3Uncharacterized protein. (204 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (487 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (146 aa)
STAT6Signal transducer and activator of transcription. (849 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (602 aa)
SASH3SAM and SH3 domain containing 3. (375 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
SLAMF7SLAM family member 7. (336 aa)
CD48Ig-like domain-containing protein. (203 aa)
TRAF3IP2TRAF3 interacting protein 2. (562 aa)
IFNKInterferon kappa. (174 aa)
CARD11Caspase recruitment domain family member 11. (1159 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (150 aa)
RC3H1Ring finger and CCCH-type domains 1. (1097 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
EOMESEomesodermin. (700 aa)
CD8ACD8a molecule. (235 aa)
RABL3RAB, member of RAS oncogene family like 3. (236 aa)
TNFRSF4TNF receptor superfamily member 4. (265 aa)
LEPRLeptin receptor. (835 aa)
RC3H2Ring finger and CCCH-type domains 2. (1189 aa)
FOXP3Forkhead box P3. (427 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (760 aa)
GATA3GATA binding protein 3. (443 aa)
PATZ1POZ/BTB and AT hook containing zinc finger 1. (687 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1291 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
SLC11A1Solute carrier family 11 member 1. (541 aa)
RASGRP1RAS guanyl releasing protein 1. (792 aa)
HLXH2.0 like homeobox. (491 aa)
FGL2Fibrinogen like 2. (440 aa)
CLEC4DC-type lectin domain family 4 member D. (212 aa)
IL20RBInterfer-bind domain-containing protein. (94 aa)
RORARAR related orphan receptor A. (467 aa)
BCL2BCL2 apoptosis regulator. (229 aa)
IKZF3IKAROS family zinc finger 3. (509 aa)
RHOHRas homolog family member H. (191 aa)
HSPD1Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa)
FOXP1Fork-head domain-containing protein. (683 aa)
ZAP70Tyrosine-protein kinase. (629 aa)
G3ULT4_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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