STRINGSTRING
ALAD ALAD SOCS5 SOCS5 G3UHK4_LOXAF G3UHK4_LOXAF SH3RF2 SH3RF2 TNFAIP3 TNFAIP3 G3UIB4_LOXAF G3UIB4_LOXAF GCLC GCLC DVL1 DVL1 GIPC2 GIPC2 G3UK83_LOXAF G3UK83_LOXAF HSPBP1 HSPBP1 VPS28 VPS28 PITHD1 PITHD1 RPL11 RPL11 SMAD7 SMAD7 G3ULR5_LOXAF G3ULR5_LOXAF PSME2 PSME2 PSMC3 PSMC3 G3UNR2_LOXAF G3UNR2_LOXAF HMGCR HMGCR SERPINE2 SERPINE2 G3SLA2_LOXAF G3SLA2_LOXAF CDK5RAP3 CDK5RAP3 LDLR LDLR WDR91 WDR91 PCSK9 PCSK9 PRICKLE1 PRICKLE1 MAP1A MAP1A PBK PBK NRDC NRDC OAZ2 OAZ2 RNF217 RNF217 VPS35 VPS35 CHMP6 CHMP6 PSMD2 PSMD2 C4BPB C4BPB PTPN3 PTPN3 RNF144A RNF144A USP8 USP8 MDM4 MDM4 OAZ1 OAZ1 GGA3 GGA3 AQP11 AQP11 PSMC5 PSMC5 G3SS82_LOXAF G3SS82_LOXAF F8A1 F8A1 ZYG11B ZYG11B CHEK2 CHEK2 IL1B IL1B TMF1 TMF1 FHIT FHIT RHBDD1 RHBDD1 WNT10B WNT10B NKD1 NKD1 COMMD1 COMMD1 IFNG IFNG ZYG11A ZYG11A PSMD14 PSMD14 TIMP4 TIMP4 ASB11 ASB11 RNF19A RNF19A PSMC1 PSMC1 CAMLG CAMLG TMEM9 TMEM9 GRIN2A GRIN2A PLK1 PLK1 ARIH1 ARIH1 MYLIP MYLIP COP1 COP1 DEDD DEDD OAZ3 OAZ3 VIP VIP FLNA FLNA MTM1 MTM1 USP5 USP5 APC2 APC2 WAC WAC CSNK1D CSNK1D OSBPL7 OSBPL7 TRIB3 TRIB3 GFAP GFAP PIN1 PIN1 HERPUD1 HERPUD1 BAG2 BAG2 VCP VCP IRAK3 IRAK3 RNF14 RNF14 USP7 USP7 GSK3B GSK3B GIPC3 GIPC3 DNAAF4 DNAAF4 DAB2IP DAB2IP AZIN2 AZIN2 TIPARP TIPARP CDC20B CDC20B AURKA AURKA MYCBP2 MYCBP2 PSME3IP1 PSME3IP1 OGT OGT NQO1 NQO1 DNAJB2 DNAJB2 SORL1 SORL1 PSMD3 PSMD3 BAG6 BAG6 BBS7 BBS7 AZIN1 AZIN1 AGAP2 AGAP2 CTSA CTSA USP14 USP14 EPM2A EPM2A DTL DTL OPHN1 OPHN1 PHB PHB MARCHF7 MARCHF7 PSMD1 PSMD1 SDCBP SDCBP ADAM8 ADAM8 UBQLN4 UBQLN4 TLK2 TLK2 GPLD1 GPLD1 LPCAT1 LPCAT1 CLU CLU SOCS4 SOCS4 DDB1 DDB1 MKRN2 MKRN2 ITCH ITCH RACK1 RACK1 FAF1 FAF1 PARK7 PARK7 PSMD10 PSMD10 SF3B3 SF3B3 ATRAID ATRAID TRIB1 TRIB1 USP25 USP25 ARIH2 ARIH2 USP19 USP19 GNA12 GNA12 EIF3H EIF3H ANKIB1 ANKIB1 TRIM40 TRIM40 RNFT2 RNFT2 APC APC G3TBM5_LOXAF G3TBM5_LOXAF LAPTM4A LAPTM4A TRIB2 TRIB2 TIMP3 TIMP3 RNF144B RNF144B KCNE2 KCNE2 RNF19B RNF19B SNX9 SNX9 TRIM32 TRIM32 PSMC2 PSMC2 RNFT1 RNFT1 APOE APOE EGFR EGFR CBLB CBLB DAB2 DAB2 ASB5 ASB5 UCHL5 UCHL5 PSMC6 PSMC6 STYX STYX RNF41 RNF41 CLUL1 CLUL1 RDX RDX RGP1 RGP1 PKD1 PKD1 GSK3A GSK3A SH3RF1 SH3RF1 PACSIN3 PACSIN3 MAD2L2 MAD2L2 AMER1 AMER1 LRRK2 LRRK2 FAM122A FAM122A FBXW7 FBXW7 CD81 CD81 NDFIP1 NDFIP1 SNX12 SNX12 ASB9 ASB9 GABARAPL2 GABARAPL2 FBXO22 FBXO22 CCDC84 CCDC84 BTRC BTRC VGLL4 VGLL4 GGA1 GGA1 NUDT15 NUDT15 RCHY1 RCHY1 SH3D19 SH3D19 UBXN2A UBXN2A PSMC4 PSMC4 N4BP1 N4BP1 SGTA SGTA SNX3 SNX3 PIAS1 PIAS1 UFL1 UFL1 MFSD8 MFSD8 CCAR2 CCAR2 CDC20 CDC20 DET1 DET1 CBFA2T3 CBFA2T3 LOC100668722 LOC100668722 IL10 IL10 LOC100666300 LOC100666300 PSMF1 PSMF1 SIRT2 SIRT2 RHBDD3 RHBDD3 UBXN1 UBXN1 ZDHHC2 ZDHHC2 RAB26 RAB26 FBXL5 FBXL5 TIMP1 TIMP1 LRIG2 LRIG2 BANP BANP TMTC3 TMTC3 ZER1 ZER1 G3TTE2_LOXAF G3TTE2_LOXAF XPO1 XPO1 AXIN1 AXIN1 EIF3H-2 EIF3H-2 G3TV14_LOXAF G3TV14_LOXAF G3TV18_LOXAF G3TV18_LOXAF G3TVD3_LOXAF G3TVD3_LOXAF DESI1 DESI1 STX5 STX5 DDRGK1 DDRGK1 KLHL40 KLHL40 LOC100667589 LOC100667589 G3TWY9_LOXAF G3TWY9_LOXAF PSME3 PSME3 NEDD4 NEDD4 CAV1 CAV1 AXIN2 AXIN2 G3TYP9_LOXAF G3TYP9_LOXAF ATG7 ATG7 UBE2K UBE2K NSF NSF G3TZS1_LOXAF G3TZS1_LOXAF RAD23A RAD23A DACT1 DACT1 PRKCG PRKCG SGSM3 SGSM3 SEC22B SEC22B FZR1 FZR1 G3U1Z2_LOXAF G3U1Z2_LOXAF TIMP2 TIMP2 G3U524_LOXAF G3U524_LOXAF MSN MSN SNF8 SNF8 SIRT6 SIRT6 GPC3 GPC3 RIC1 RIC1 G3U7L4_LOXAF G3U7L4_LOXAF FAM83D FAM83D RILP RILP G3U8D7_LOXAF G3U8D7_LOXAF NUB1 NUB1 PSEN1 PSEN1 SH3RF3 SH3RF3 G3UC04_LOXAF G3UC04_LOXAF GLMN GLMN SOX17 SOX17 PSME1 PSME1 BCAP31 BCAP31 USP13 USP13 BAG5 BAG5 FBXW9 FBXW9 FMR1 FMR1 NOS2 NOS2 G3UFB2_LOXAF G3UFB2_LOXAF MAPK9 MAPK9 G3UFV4_LOXAF G3UFV4_LOXAF RELA RELA DDA1 DDA1 ATP13A2 ATP13A2 STUB1 STUB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALADDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (331 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
G3UHK4_LOXAFHORMA domain-containing protein. (105 aa)
SH3RF2SH3 domain containing ring finger 2. (611 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
G3UIB4_LOXAFProtein kinase domain-containing protein. (597 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (637 aa)
DVL1Dishevelled segment polarity protein 1. (621 aa)
GIPC2GIPC PDZ domain containing family member 2. (237 aa)
G3UK83_LOXAFUncharacterized protein. (472 aa)
HSPBP1HSPA (Hsp70) binding protein 1. (356 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (224 aa)
PITHD1PITH domain containing 1. (219 aa)
RPL11Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (180 aa)
SMAD7Mothers against decapentaplegic homolog. (405 aa)
G3ULR5_LOXAFHORMA domain-containing protein. (82 aa)
PSME2Uncharacterized protein. (250 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (450 aa)
G3UNR2_LOXAFUncharacterized protein. (111 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (890 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (399 aa)
G3SLA2_LOXAFUncharacterized protein. (367 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (491 aa)
LDLRLow density lipoprotein receptor. (858 aa)
WDR91WD repeat domain 91. (739 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (660 aa)
PRICKLE1Prickle planar cell polarity protein 1. (832 aa)
MAP1AMicrotubule associated protein 1A. (2228 aa)
PBKPDZ binding kinase. (300 aa)
NRDCNardilysin convertase. (1222 aa)
OAZ2Ornithine decarboxylase antizyme 2. (185 aa)
RNF217RBR-type E3 ubiquitin transferase. (259 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
CHMP6Charged multivesicular body protein 6. (200 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (907 aa)
C4BPBComplement component 4 binding protein beta. (248 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (913 aa)
RNF144ARBR-type E3 ubiquitin transferase. (292 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1079 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa)
OAZ1Ornithine decarboxylase antizyme 1. (179 aa)
GGA3Golgi associated, gamma adaptin ear containing, ARF binding protein 3. (718 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (272 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
G3SS82_LOXAFUncharacterized protein. (90 aa)
F8A1Uncharacterized protein. (375 aa)
ZYG11BZyg-11 family member B, cell cycle regulator. (744 aa)
CHEK2Checkpoint kinase 2. (550 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (262 aa)
TMF1TATA element modulatory factor 1. (1093 aa)
FHITUncharacterized protein. (47 aa)
RHBDD1Rhomboid domain containing 1. (288 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (470 aa)
COMMD1COMM domain-containing protein. (101 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
ZYG11AZyg-11 family member A, cell cycle regulator. (720 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
TIMP4TIMP metallopeptidase inhibitor 4. (224 aa)
ASB11Ankyrin repeat and SOCS box containing 11. (323 aa)
RNF19ARBR-type E3 ubiquitin transferase. (838 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (296 aa)
TMEM9Transmembrane protein 9. (183 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1327 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
ARIH1RBR-type E3 ubiquitin transferase. (432 aa)
MYLIPMyosin regulatory light chain interacting protein. (445 aa)
COP1COP1 E3 ubiquitin ligase. (727 aa)
DEDDDeath effector domain containing. (318 aa)
OAZ3Ornithine decarboxylase antizyme 3. (232 aa)
VIPVasoactive intestinal peptide. (170 aa)
FLNAFilamin A. (2521 aa)
MTM1Myotubularin 1. (603 aa)
USP5Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (858 aa)
APC2APC regulator of WNT signaling pathway 2. (2096 aa)
WACWW domain containing adaptor with coiled-coil. (646 aa)
CSNK1DCasein kinase 1 delta. (416 aa)
OSBPL7Oxysterol-binding protein; Belongs to the OSBP family. (859 aa)
TRIB3Tribbles pseudokinase 3. (358 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (432 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (423 aa)
BAG2BCL2 associated athanogene 2. (212 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (802 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (588 aa)
RNF14RBR-type E3 ubiquitin transferase. (473 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1078 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
GIPC3GIPC PDZ domain containing family member 3. (344 aa)
DNAAF4Dynein axonemal assembly factor 4. (410 aa)
DAB2IPDAB2 interacting protein. (1189 aa)
AZIN2Antizyme inhibitor 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (415 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (658 aa)
CDC20BCell division cycle 20B. (486 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (403 aa)
MYCBP2MYC binding protein 2. (4717 aa)
PSME3IP1Family with sequence similarity 192 member A. (255 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (273 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (323 aa)
SORL1Sortilin related receptor 1. (2220 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (533 aa)
BAG6BCL2 associated athanogene 6. (1151 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
AZIN1Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (448 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1191 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (475 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (493 aa)
EPM2AEPM2A glucan phosphatase, laforin. (325 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (732 aa)
OPHN1Oligophrenin 1. (803 aa)
PHBProhibitin. (272 aa)
MARCHF7Membrane associated ring-CH-type finger 7. (688 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (948 aa)
SDCBPSyndecan binding protein. (297 aa)
ADAM8ADAM metallopeptidase domain 8. (824 aa)
UBQLN4Ubiquilin 4. (601 aa)
TLK2Tousled like kinase 2. (750 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (840 aa)
LPCAT1Uncharacterized protein. (477 aa)
CLUClusterin; Belongs to the clusterin family. (418 aa)
SOCS4Suppressor of cytokine signaling 4. (437 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
MKRN2Makorin ring finger protein 2. (414 aa)
ITCHE3 ubiquitin-protein ligase. (865 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
FAF1Fas associated factor 1. (377 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
PSMD10ANK_REP_REGION domain-containing protein. (226 aa)
SF3B3Splicing factor 3b subunit 3. (1217 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (230 aa)
TRIB1Tribbles pseudokinase 1. (372 aa)
USP25Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (966 aa)
ARIH2RBR-type E3 ubiquitin transferase. (496 aa)
USP19Ubiquitin specific peptidase 19. (1361 aa)
GNA12G protein subunit alpha 12. (373 aa)
EIF3HEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (352 aa)
ANKIB1RBR-type E3 ubiquitin transferase. (1092 aa)
TRIM40Tripartite motif containing 40. (227 aa)
RNFT2Ring finger protein, transmembrane 2. (450 aa)
APCAPC regulator of WNT signaling pathway. (2836 aa)
G3TBM5_LOXAFWD_REPEATS_REGION domain-containing protein. (142 aa)
LAPTM4ALysosomal protein transmembrane 4 alpha. (255 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
TIMP3TIMP metallopeptidase inhibitor 3. (211 aa)
RNF144BRBR-type E3 ubiquitin transferase. (303 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
RNF19BRBR-type E3 ubiquitin transferase. (522 aa)
SNX9Sorting nexin. (594 aa)
TRIM32Tripartite motif containing 32. (654 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
RNFT1Ring finger protein, transmembrane 1. (399 aa)
APOEApolipoprotein E. (314 aa)
EGFRReceptor protein-tyrosine kinase. (1206 aa)
CBLBCbl proto-oncogene B. (983 aa)
DAB2DAB adaptor protein 2. (768 aa)
ASB5Ankyrin repeat and SOCS box containing 5. (329 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (329 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
STYXSerine/threonine/tyrosine interacting protein. (223 aa)
RNF41Ring finger protein 41. (318 aa)
CLUL1CLb domain-containing protein. (328 aa)
RDXRadixin. (600 aa)
RGP1RGP1 homolog, RAB6A GEF complex partner 1. (391 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4255 aa)
GSK3AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (482 aa)
SH3RF1SH3 domain containing ring finger 1. (883 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons 3. (424 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
AMER1APC membrane recruitment protein 1. (1131 aa)
LRRK2Uncharacterized protein. (874 aa)
FAM122AFamily with sequence similarity 122A. (285 aa)
FBXW7F-box and WD repeat domain containing 7. (710 aa)
CD81Tetraspanin. (214 aa)
NDFIP1Nedd4 family interacting protein 1. (221 aa)
SNX12Sorting nexin 12. (162 aa)
ASB9Ankyrin repeat and SOCS box containing 9. (263 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
FBXO22F-box protein 22. (392 aa)
CCDC84Coiled-coil domain containing 84. (330 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (593 aa)
VGLL4Vestigial like family member 4. (296 aa)
GGA1Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (636 aa)
NUDT15Nudix hydrolase 15; Belongs to the Nudix hydrolase family. (164 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (259 aa)
SH3D19SH3 domain containing 19. (787 aa)
UBXN2AUBX domain protein 2A. (257 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
N4BP1NEDD4 binding protein 1. (825 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (315 aa)
SNX3Sorting nexin 3. (162 aa)
PIAS1Protein inhibitor of activated STAT 1. (642 aa)
UFL1UFM1 specific ligase 1. (792 aa)
MFSD8Major facilitator superfamily domain containing 8. (519 aa)
CCAR2Cell cycle and apoptosis regulator 2. (922 aa)
CDC20Cell division cycle 20. (499 aa)
DET1Uncharacterized protein. (550 aa)
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (612 aa)
LOC100668722HORMA domain-containing protein. (205 aa)
IL10Interleukin 10. (178 aa)
LOC100666300Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
PSMF1Proteasome inhibitor subunit 1. (270 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (392 aa)
RHBDD3Rhomboid domain containing 3. (386 aa)
UBXN1UBX domain protein 1. (297 aa)
ZDHHC2Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (353 aa)
RAB26RAB26, member RAS oncogene family. (256 aa)
FBXL5F-box and leucine rich repeat protein 5. (691 aa)
TIMP1TIMP metallopeptidase inhibitor 1. (207 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1051 aa)
BANPBTG3 associated nuclear protein. (551 aa)
TMTC3Transmembrane O-mannosyltransferase targeting cadherins 3. (920 aa)
ZER1Zyg-11 related cell cycle regulator. (758 aa)
G3TTE2_LOXAFUncharacterized protein. (233 aa)
XPO1Exportin 1. (1073 aa)
AXIN1Axin 1. (864 aa)
EIF3H-2Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (334 aa)
G3TV14_LOXAFRBR-type E3 ubiquitin transferase. (406 aa)
G3TV18_LOXAFUncharacterized protein. (86 aa)
G3TVD3_LOXAFEF-hand domain-containing protein. (102 aa)
DESI1Desumoylating isopeptidase 1. (139 aa)
STX5Syntaxin 5; Belongs to the syntaxin family. (354 aa)
DDRGK1DDRGK domain containing 1. (317 aa)
KLHL40Kelch like family member 40. (420 aa)
LOC100667589HORMA domain-containing protein. (205 aa)
G3TWY9_LOXAFANK_REP_REGION domain-containing protein. (225 aa)
PSME3Proteasome activator subunit 3. (265 aa)
NEDD4E3 ubiquitin-protein ligase. (845 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (185 aa)
AXIN2Axin 2. (820 aa)
G3TYP9_LOXAFHORMA domain-containing protein. (89 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (699 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (203 aa)
NSFN-ethylmaleimide sensitive factor, vesicle fusing ATPase. (741 aa)
G3TZS1_LOXAFPlsC domain-containing protein. (488 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (363 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (800 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (693 aa)
SGSM3Small G protein signaling modulator 3. (727 aa)
SEC22BSEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa)
FZR1Fizzy and cell division cycle 20 related 1. (452 aa)
G3U1Z2_LOXAFCarboxypeptidase; Belongs to the peptidase S10 family. (463 aa)
TIMP2TIMP metallopeptidase inhibitor 2. (196 aa)
G3U524_LOXAFHORMA domain-containing protein. (89 aa)
MSNMoesin. (578 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
SIRT6Sirtuin 6. (336 aa)
GPC3Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (472 aa)
RIC1RIC1 homolog, RAB6A GEF complex partner 1. (1421 aa)
G3U7L4_LOXAFCOMMD1_N domain-containing protein. (60 aa)
FAM83DFamily with sequence similarity 83 member D. (585 aa)
RILPRab interacting lysosomal protein. (385 aa)
G3U8D7_LOXAFUncharacterized protein. (202 aa)
NUB1Negative regulator of ubiquitin like proteins 1. (615 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (440 aa)
SH3RF3SH3 domain containing ring finger 3. (699 aa)
G3UC04_LOXAFUncharacterized protein. (327 aa)
GLMNGlomulin, FKBP associated protein. (599 aa)
SOX17SRY-box transcription factor 17. (391 aa)
PSME1Proteasome activator subunit 1. (249 aa)
BCAP31B cell receptor associated protein 31. (249 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (866 aa)
BAG5BCL2 associated athanogene 5. (447 aa)
FBXW9F-box and WD repeat domain containing 9. (299 aa)
FMR1Fragile X mental retardation 1. (619 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1155 aa)
G3UFB2_LOXAFPA28_beta domain-containing protein. (141 aa)
MAPK9Mitogen-activated protein kinase. (431 aa)
G3UFV4_LOXAFUncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (112 aa)
RELARELA proto-oncogene, NF-kB subunit. (555 aa)
DDA1DET1 and DDB1 associated 1. (101 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1178 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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