STRINGSTRING
TTK TTK ZW10 ZW10 TRIP13 TRIP13 G3UHK4_LOXAF G3UHK4_LOXAF G3U5J0_LOXAF G3U5J0_LOXAF G3U524_LOXAF G3U524_LOXAF NME6 NME6 HASPIN HASPIN G3TYP9_LOXAF G3TYP9_LOXAF LOC100667589 LOC100667589 CHEK1 CHEK1 LOC100668722 LOC100668722 KNTC1 KNTC1 KLHL22 KLHL22 APC APC MTBP MTBP BUB3 BUB3 KHDC3L KHDC3L TOM1L1 TOM1L1 BUB1B BUB1B PSMG2 PSMG2 MAD1L1 MAD1L1 BUB1 BUB1 ATM ATM BIRC5 BIRC5 PLK1 PLK1 TPR TPR ZNF207 ZNF207 FBXO5 FBXO5 G3ULR5_LOXAF G3ULR5_LOXAF SPDL1 SPDL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TTKTTK protein kinase. (841 aa)
ZW10Zw10 kinetochore protein. (781 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (348 aa)
G3UHK4_LOXAFHORMA domain-containing protein. (105 aa)
G3U5J0_LOXAFMOEP19 domain-containing protein. (158 aa)
G3U524_LOXAFHORMA domain-containing protein. (89 aa)
NME6Nucleoside diphosphate kinase. (188 aa)
HASPINHistone H3 associated protein kinase. (773 aa)
G3TYP9_LOXAFHORMA domain-containing protein. (89 aa)
LOC100667589HORMA domain-containing protein. (205 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (475 aa)
LOC100668722HORMA domain-containing protein. (205 aa)
KNTC1Kinetochore associated 1. (2214 aa)
KLHL22BTB domain-containing protein. (637 aa)
APCAPC regulator of WNT signaling pathway. (2836 aa)
MTBPMDM2 binding protein. (904 aa)
BUB3BUB3 mitotic checkpoint protein. (325 aa)
KHDC3LMOEP19 domain-containing protein. (118 aa)
TOM1L1Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. (475 aa)
BUB1BUncharacterized protein. (1061 aa)
PSMG2Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family. (264 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (718 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1061 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3055 aa)
BIRC5Baculoviral IAP repeat containing 5. (140 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
TPRTranslocated promoter region, nuclear basket protein. (2362 aa)
ZNF207Zinc finger protein 207. (497 aa)
FBXO5F-box protein 5. (442 aa)
G3ULR5_LOXAFHORMA domain-containing protein. (82 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (555 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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