STRINGSTRING
GADD45A GADD45A MAP2K4 MAP2K4 TRAF4 TRAF4 MMP8 MMP8 MBIP MBIP NOD1 NOD1 TNFSF11 TNFSF11 AGER AGER TIRAP TIRAP RIPK1 RIPK1 WNT16 WNT16 TNFRSF19 TNFRSF19 SERPINF2 SERPINF2 MFHAS1 MFHAS1 FLT4 FLT4 DUSP19 DUSP19 SLAMF1 SLAMF1 DAB2IP DAB2IP PYCARD PYCARD PTK2B PTK2B MAP2K7 MAP2K7 RASSF2 RASSF2 APP APP TRAF5 TRAF5 PLCB1 PLCB1 CCN2 CCN2 TPD52L1 TPD52L1 WNT7B WNT7B PJA2 PJA2 WNT7A WNT7A RASGRP1 RASGRP1 EDAR EDAR MAP3K5 MAP3K5 RB1CC1 RB1CC1 BIRC7 BIRC7 SH3RF2 SH3RF2 G3UGU2_LOXAF G3UGU2_LOXAF TRPV4 TRPV4 MAPK8IP3 MAPK8IP3 MAPKBP1 MAPKBP1 CCL19 CCL19 SH3RF3 SH3RF3 EDA2R EDA2R MYD88 MYD88 RIPK2 RIPK2 DUSP22 DUSP22 LTBR LTBR ANKRD6 ANKRD6 MAP3K11 MAP3K11 GADD45G GADD45G MAPK8IP1 MAPK8IP1 CRK CRK G3TWY0_LOXAF G3TWY0_LOXAF TRAF6 TRAF6 DIXDC1 DIXDC1 AXIN1 AXIN1 ZNF622 ZNF622 CARD9 CARD9 CCL21 CCL21 CD27 CD27 TRAF2 TRAF2 TRAF1 TRAF1 NOD2 NOD2 MINK1 MINK1 TAOK3 TAOK3 SH3RF1 SH3RF1 G3THL4_LOXAF G3THL4_LOXAF CRACR2A CRACR2A GADD45B GADD45B TRAF3 TRAF3 NCF1 NCF1 TNIK TNIK TLR3 TLR3 UNC5CL UNC5CL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GADD45AGrowth arrest and DNA damage inducible alpha. (146 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (326 aa)
TRAF4TNF receptor-associated factor. (470 aa)
MMP8Matrix metallopeptidase 8. (468 aa)
MBIPMAP3K12 binding inhibitory protein 1. (345 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
TNFSF11Tumor necrosis factor ligand 6B; Belongs to the tumor necrosis factor family. (319 aa)
AGERAdvanced glycosylation end-product specific receptor. (402 aa)
TIRAPTIR domain containing adaptor protein. (221 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (672 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
TNFRSF19TNF receptor superfamily member 19. (250 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (488 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1052 aa)
FLT4Fms related tyrosine kinase 4. (1271 aa)
DUSP19Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (207 aa)
SLAMF1Ig-like domain-containing protein. (341 aa)
DAB2IPDAB2 interacting protein. (1189 aa)
PYCARDPYD and CARD domain containing. (199 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1011 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (497 aa)
RASSF2Ras association domain family member 2. (326 aa)
APPAmyloid beta precursor protein. (751 aa)
TRAF5TNF receptor-associated factor. (434 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1089 aa)
CCN2Cellular communication network factor 2. (338 aa)
TPD52L1TPD52 like 1. (206 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
PJA2Praja ring finger ubiquitin ligase 2. (709 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
RASGRP1RAS guanyl releasing protein 1. (792 aa)
EDAREctodysplasin A receptor. (438 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1371 aa)
RB1CC1ATG11 domain-containing protein. (1595 aa)
BIRC7Baculoviral IAP repeat containing 7. (245 aa)
SH3RF2SH3 domain containing ring finger 2. (611 aa)
G3UGU2_LOXAFATG11 domain-containing protein. (216 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (739 aa)
MAPK8IP3Mitogen-activated protein kinase 8 interacting protein 3. (1350 aa)
MAPKBP1Mitogen-activated protein kinase binding protein 1. (1512 aa)
CCL19C-C motif chemokine. (103 aa)
SH3RF3SH3 domain containing ring finger 3. (699 aa)
EDA2REctodysplasin A2 receptor. (285 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (293 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa)
DUSP22Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (205 aa)
LTBRLymphotoxin beta receptor. (418 aa)
ANKRD6Ankyrin repeat domain 6. (728 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase 11. (781 aa)
GADD45GGrowth arrest and DNA damage inducible gamma. (159 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (706 aa)
CRKCRK proto-oncogene, adaptor protein. (307 aa)
G3TWY0_LOXAFUncharacterized protein. (88 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
DIXDC1DIX domain containing 1. (688 aa)
AXIN1Axin 1. (864 aa)
ZNF622Zinc finger protein 622. (479 aa)
CARD9Caspase recruitment domain family member 9. (537 aa)
CCL21SCY domain-containing protein. (110 aa)
CD27CD27 molecule. (261 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (509 aa)
TRAF1TNF receptor-associated factor. (409 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1020 aa)
MINK1Misshapen like kinase 1. (1341 aa)
TAOK3TAO kinase 3. (898 aa)
SH3RF1SH3 domain containing ring finger 1. (883 aa)
G3THL4_LOXAFUncharacterized protein. (146 aa)
CRACR2AEF-hand domain-containing protein. (314 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (160 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (565 aa)
NCF1Neutrophil cytosolic factor 1. (409 aa)
TNIKTRAF2 and NCK interacting kinase. (1269 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
UNC5CLUnc-5 family C-terminal like. (515 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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