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| | KLF10 | Kruppel like factor 10. (480 aa) |
| | RORA | RAR related orphan receptor A. (467 aa) |
| | PER3 | Period circadian regulator 3. (1018 aa) |
| | DYRK1A | Dual specificity tyrosine phosphorylation regulated kinase 1A. (760 aa) |
| | ASS1 | Argininosuccinate synthase 1. (412 aa) |
| | AANAT | Aralkylamine N-acetyltransferase. (207 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (795 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa) |
| | LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (907 aa) |
| | RBM4B | RNA binding motif protein 4B. (359 aa) |
| | HES7 | Hes family bHLH transcription factor 7. (225 aa) |
| | ARNTL2 | Aryl hydrocarbon receptor nuclear translocator like 2. (482 aa) |
| | PML | Promyelocytic leukemia. (861 aa) |
| | CIART | Circadian associated repressor of transcription. (381 aa) |
| | CRTC1 | CREB regulated transcription coactivator 1. (611 aa) |
| | NGFR | Nerve growth factor receptor. (414 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (487 aa) |
| | ADNP | Activity dependent neuroprotector homeobox. (1101 aa) |
| | ENOX1 | Ecto-NOX disulfide-thiol exchanger 1. (663 aa) |
| | GAS2 | Growth arrest specific 2. (314 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (648 aa) |
| | TIMELESS | Timeless circadian regulator. (1199 aa) |
| | C3orf70 | Chromosome 3 open reading frame 70. (247 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | BHLHE40 | Basic helix-loop-helix family member e40. (412 aa) |
| | CASP2 | Caspase 2; Belongs to the peptidase C14A family. (452 aa) |
| | CIPC | CLOCK interacting pacemaker. (400 aa) |
| | MYBBP1A | MYB binding protein 1a. (1315 aa) |
| | SUV39H1 | Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (364 aa) |
| | PAX4 | Paired box 4. (350 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (487 aa) |
| | MC3R | Melanocortin 3 receptor. (323 aa) |
| | OPN4 | Opsin 4. (472 aa) |
| | USP2 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (576 aa) |
| | SCAPER | S-phase cyclin A associated protein in the ER. (1403 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | DRD2 | Dopamine receptor D2. (447 aa) |
| | CSNK1D | Casein kinase 1 delta. (416 aa) |
| | ID2 | Inhibitor of DNA binding 2. (134 aa) |
| | NTRK2 | Tyrosine-protein kinase receptor. (820 aa) |
| | GDF10 | Bone morphogenetic protein 3; Belongs to the TGF-beta family. (473 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa) |
| | PAM | Peptidylglycine alpha-amidating monooxygenase. (975 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1078 aa) |
| | TPH1 | BH4_AAA_HYDROXYL_2 domain-containing protein. (222 aa) |
| | TRPM2 | Transient receptor potential cation channel subfamily M member 2. (1500 aa) |
| | HDAC3 | Hist_deacetyl domain-containing protein. (349 aa) |
| | SGPL1 | Sphingosine-1-phosphate lyase 1. (568 aa) |
| | RELB | RELB proto-oncogene, NF-kB subunit. (547 aa) |
| | ADCY1 | Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (627 aa) |
| | MYCBP2 | MYC binding protein 2. (4717 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1461 aa) |
| | SIRT1 | Sirtuin 1. (605 aa) |
| | CLOCK | Clock circadian regulator. (849 aa) |
| | THRAP3 | Thyroid hormone receptor associated protein 3. (955 aa) |
| | SLIT3 | Uncharacterized protein. (750 aa) |
| | TNFAIP6 | TNF alpha induced protein 6. (277 aa) |
| | KDM5A | Lysine demethylase 5A. (1582 aa) |
| | GPR157 | G protein-coupled receptor 157. (335 aa) |
| | KCNH7 | Potassium voltage-gated channel subfamily H member 7. (1098 aa) |
| | EREG | Epiregulin. (163 aa) |
| | NAGLU | N-acetyl-alpha-glucosaminidase. (738 aa) |
| | BMPR1B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1091 aa) |
| | CAVIN3 | Caveolae associated protein 3. (261 aa) |
| | PER2 | Period circadian regulator 2. (1252 aa) |
| | PTX3 | Pentraxin 3. (383 aa) |
| | LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (631 aa) |
| | GRIN3A | Glutamate ionotropic receptor NMDA type subunit 3A. (785 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1140 aa) |
| | PRKDC | Uncharacterized protein. (221 aa) |
| | RACK1 | Receptor for activated C kinase 1. (317 aa) |
| | ATF4 | Activating transcription factor 4. (379 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (466 aa) |
| | PER1 | Period circadian regulator 1. (1287 aa) |
| | EP300 | E1A binding protein p300. (2420 aa) |
| | RORB | RAR related orphan receptor B. (518 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | IMPDH2 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (796 aa) |
| | DBP | D-box binding PAR bZIP transcription factor. (325 aa) |
| | TEF | TEF transcription factor, PAR bZIP family member. (303 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (468 aa) |
| | NONO | Non-POU domain containing octamer binding. (472 aa) |
| | STAT5B | Signal transducer and activator of transcription. (787 aa) |
| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
| | METTL3 | Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa) |
| | DRD4 | Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (356 aa) |
| | ID4 | Inhibitor of DNA binding 4, HLH protein. (161 aa) |
| | HUWE1 | HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4372 aa) |
| | ESR1 | NR LBD domain-containing protein. (232 aa) |
| | AHR | Uncharacterized protein. (801 aa) |
| | GPR149 | G protein-coupled receptor 149. (745 aa) |
| | CCDC90B | Uncharacterized protein. (254 aa) |
| | CREBBP | CREB binding protein. (2433 aa) |
| | GPR176 | G protein-coupled receptor 176. (505 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa) |
| | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1. (966 aa) |
| | HTR7 | 5-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (452 aa) |
| | SFPQ | Splicing factor proline and glutamine rich. (704 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa) |
| | HLF | HLF transcription factor, PAR bZIP family member. (295 aa) |
| | NFYA | Nuclear transcription factor Y subunit alpha. (347 aa) |
| | NR0B2 | Nuclear receptor subfamily 0 group B member 2. (260 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (710 aa) |
| | FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (691 aa) |
| | NOCT | Nocturnin. (368 aa) |
| | SETX | Uncharacterized protein. (1281 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (744 aa) |
| | BTBD9 | BTB domain containing 9. (389 aa) |
| | ZFHX3 | Zinc finger homeobox 3. (3700 aa) |
| | RAI1 | Retinoic acid induced 1. (1821 aa) |
| | SLIT2 | Slit guidance ligand 2. (1522 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) |
| | MMP19 | Matrix metallopeptidase 19. (511 aa) |
| | MTTP | Microsomal triglyceride transfer protein. (894 aa) |
| | SP1 | Sp1 transcription factor. (784 aa) |
| | PTN | Pleiotrophin. (168 aa) |
| | CCAR2 | Cell cycle and apoptosis regulator 2. (922 aa) |
| | KDM8 | Lysine demethylase 8. (416 aa) |
| | HOMER1 | Homer scaffold protein 1. (355 aa) |
| | RORC | RAR related orphan receptor C. (517 aa) |
| | SUV39H2 | Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (403 aa) |
| | PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa) |
| | LOC100666300 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa) |
| | NDUFA9 | Uncharacterized protein. (157 aa) |
| | NCOR2 | Nuclear receptor corepressor 2. (2467 aa) |
| | ATOH7 | Atonal bHLH transcription factor 7. (152 aa) |
| | ID1 | Inhibitor of DNA binding 1, HLH protein. (154 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1087 aa) |
| | TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (770 aa) |
| | G3TS21_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (363 aa) |
| | KIAA2013 | KIAA2013. (627 aa) |
| | HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (824 aa) |
| | ZNF830 | Zinc finger protein 830. (346 aa) |
| | RBM4 | RNA binding motif protein 4. (365 aa) |
| | NFIL3 | Nuclear factor interleukin-3-regulated protein; Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T- cells. Competes for the same consensus-binding site with PAR DNA- bi [...] (462 aa) |
| | ARNTL | Aryl hydrocarbon receptor nuclear translocator like. (620 aa) |
| | G3TWD5_LOXAF | Uncharacterized protein. (74 aa) |
| | ID3 | Inhibitor of DNA binding 3, HLH protein. (119 aa) |
| | CRY1 | Cryptochrome circadian regulator 1. (606 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (699 aa) |
| | ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase 2. (892 aa) |
| | NUDT12 | Nudix hydrolase 12. (463 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (693 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (282 aa) |
| | ATF5 | Activating transcription factor 5. (276 aa) |
| | INHBA | Inhibin subunit beta A. (422 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (548 aa) |
| | FAM155A | Family with sequence similarity 155 member A. (275 aa) |
| | SIRT6 | Sirtuin 6. (336 aa) |
| | G3U6D1_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (364 aa) |
| | NPAS2 | Neuronal PAS domain protein 2. (810 aa) |
| | PSPC1 | Paraspeckle component 1. (523 aa) |
| | G3U6U6_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa) |
| | G3U7L3_LOXAF | PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (140 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (611 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) |
| | NMS | Neuromedin S. (147 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (428 aa) |
| | CARTPT | CART prepropeptide. (128 aa) |
| | G3UAZ0_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (364 aa) |
| | AXL | AXL receptor tyrosine kinase. (889 aa) |
| | G3UBE5_LOXAF | Uncharacterized protein. (152 aa) |
| | FSHB | Follicle stimulating hormone subunit beta. (135 aa) |
| | CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1161 aa) |
| | G3UCX2_LOXAF | BHLH domain-containing protein. (364 aa) |
| | G3UDE4_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (362 aa) |
| | G3UDK4_LOXAF | Vert_IL3-reg_TF domain-containing protein. (434 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (536 aa) |
| | FBXW9 | F-box and WD repeat domain containing 9. (299 aa) |
| | NRIP1 | Nuclear receptor interacting protein 1. (1159 aa) |
| | NOS2 | Nitric oxide synthase; Produces nitric oxide (NO). (1155 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (431 aa) |
| | MAGED1 | MAGE family member D1. (757 aa) |
| | KDM2A | Lysine demethylase 2A. (1161 aa) |
| | G3UHE5_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa) |
| | KDM5B | Lysine demethylase 5B. (1476 aa) |
| | NR1D2 | Nuclear receptor subfamily 1 group D member 2. (576 aa) |
| | NAMPT | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (497 aa) |
| | G3UHY3_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (288 aa) |
| | CRY2 | Cryptochrome circadian regulator 2. (592 aa) |
| | G3UI57_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (360 aa) |
| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1537 aa) |
| | G3UIZ7_LOXAF | Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (476 aa) |
| | G3UJ00_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (360 aa) |
| | ENOX2 | Ecto-NOX disulfide-thiol exchanger 2. (601 aa) |
| | G3UJA9_LOXAF | Uncharacterized protein. (400 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (533 aa) |
| | G3UK14_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (365 aa) |
| | DHX9 | DExH-box helicase 9. (1289 aa) |
| | G3UKJ5_LOXAF | Uncharacterized protein. (587 aa) |
| | NCOR1 | Nuclear receptor corepressor 1. (2457 aa) |
| | G3ULT4_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa) |
| | MTA1 | Metastasis associated 1. (660 aa) |
| | G3UNE7_LOXAF | Uncharacterized protein. (214 aa) |
