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MED1 MED1 MAEA MAEA EPB42 EPB42 BAP1 BAP1 ERCC2 ERCC2 SLC4A1 SLC4A1 SH2B3 SH2B3 ARID4A ARID4A ADGRF5 ADGRF5 SRF SRF G6PD G6PD NCKAP1L NCKAP1L BCL6 BCL6 DMTN DMTN LYAR LYAR EPO EPO ABCB10 ABCB10 JMJD6 JMJD6 PLA2G10 PLA2G10 GATA1 GATA1 CITED2 CITED2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1570 aa)
MAEAMacrophage erythroblast attacher. (396 aa)
EPB42Erythrocyte membrane protein band 4.2. (691 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (729 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
SLC4A1Anion exchange protein. (904 aa)
SH2B3SH2B adaptor protein 3. (568 aa)
ARID4AAT-rich interaction domain 4A. (1268 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1271 aa)
SRFSerum response factor. (391 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa)
NCKAP1LNCK associated protein 1 like. (1136 aa)
BCL6BCL6 transcription repressor. (708 aa)
DMTNDematin actin binding protein. (384 aa)
LYARLy1 antibody reactive. (377 aa)
EPOErythropoietin. (208 aa)
ABCB10ATP binding cassette subfamily B member 10. (601 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (367 aa)
PLA2G10Phospholipase A(2). (152 aa)
GATA1GATA binding protein 1. (408 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (253 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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