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| | BNC2 | Basonuclin 2. (1118 aa) |
| | SLC10A7 | Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (340 aa) |
| | SULF2 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (884 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (405 aa) |
| | OSTN | Osteocrin. (100 aa) |
| | INPPL1 | Inositol polyphosphate phosphatase like 1. (1265 aa) |
| | HAS2 | Hyaluronan synthase 2. (552 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1570 aa) |
| | ZNF385A | Zinc finger protein 385A. (312 aa) |
| | DDR2 | Discoidin domain receptor tyrosine kinase 2. (855 aa) |
| | ITGB6 | Integrin beta; Belongs to the integrin beta chain family. (788 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1291 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | BGN | Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (368 aa) |
| | MMP14 | Matrix metallopeptidase 14. (583 aa) |
| | INSIG2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) |
| | LEPR | Leptin receptor. (835 aa) |
| | SERPINH1 | Serpin family H member 1; Belongs to the serpin family. (419 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | MCPH1 | BRCT domain-containing protein. (634 aa) |
| | CCDC154 | Uncharacterized protein. (394 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | SMAD5 | Mothers against decapentaplegic homolog. (465 aa) |
| | IMPAD1 | Inositol monophosphatase domain containing 1. (357 aa) |
| | TRIP11 | GRIP domain-containing protein. (1688 aa) |
| | TULP3 | Tubby-like protein; Belongs to the TUB family. (467 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | TRIM45 | Tripartite motif containing 45. (530 aa) |
| | G3SW83_LOXAF | EXPERA domain-containing protein. (232 aa) |
| | THBS3 | Thrombospondin 3. (956 aa) |
| | MMP13 | Matrix metallopeptidase 13. (471 aa) |
| | WASF2 | WASP family member 2. (497 aa) |
| | ASXL1 | ASXL transcriptional regulator 1. (1429 aa) |
| | BBX | BBX high mobility group box domain containing. (854 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (487 aa) |
| | PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (411 aa) |
| | RAB23 | RAB23, member RAS oncogene family. (237 aa) |
| | SH2B3 | SH2B adaptor protein 3. (568 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa) |
| | PEX7 | Peroxisomal biogenesis factor 7. (322 aa) |
| | NSD2 | Nuclear receptor binding SET domain protein 2. (1361 aa) |
| | RARG | Retinoic acid receptor gamma. (452 aa) |
| | SNX10 | Sorting nexin 10. (201 aa) |
| | LRRK1 | Leucine rich repeat kinase 1. (2015 aa) |
| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (464 aa) |
| | SBDS | SBDS ribosome maturation factor. (250 aa) |
| | SULF1 | Sulfatase 1. (857 aa) |
| | GLI3 | GLI family zinc finger 3. (1586 aa) |
| | FREM1 | FRAS1 related extracellular matrix 1. (1462 aa) |
| | ATG9A | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (842 aa) |
| | OSR2 | Odd-skipped related transciption factor 2. (276 aa) |
| | CHAD | Chondroadherin. (359 aa) |
| | MMP16 | Matrix metallopeptidase 16. (607 aa) |
| | ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif 7. (1569 aa) |
| | SRF | Serum response factor. (391 aa) |
| | EVC | EvC ciliary complex subunit 1. (771 aa) |
| | AKAP13 | Uncharacterized protein. (2466 aa) |
| | PHEX | Phosphate regulating endopeptidase homolog X-linked. (748 aa) |
| | VPS33B | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (613 aa) |
| | EXT2 | Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (718 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | BMPR1B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa) |
| | TNFSF11 | Tumor necrosis factor ligand 6B; Belongs to the tumor necrosis factor family. (319 aa) |
| | GJA1 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa) |
| | TFAP2A | Transcription factor AP-2 alpha. (438 aa) |
| | PAPPA2 | Pappalysin 2. (1262 aa) |
| | TMEM107 | Transmembrane protein 107. (144 aa) |
| | CYP26B1 | Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa) |
| | EP300 | E1A binding protein p300. (2420 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | MIGA2 | Mitoguardin 2. (593 aa) |
| | MATN1 | Matrilin 1. (498 aa) |
| | SEMA4D | Sema domain-containing protein; Belongs to the semaphorin family. (302 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | BMP2 | Bone morphogenetic protein 2. (395 aa) |
| | BMP6 | Bone morphogenetic protein 6. (298 aa) |
| | ZFPM1 | Zinc finger protein, FOG family member 1. (760 aa) |
| | HOXB4 | Homeobox B4. (251 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (473 aa) |
| | FLI1 | Fli-1 proto-oncogene, ETS transcription factor. (452 aa) |
| | MSX1 | Msh homeobox 1. (297 aa) |
| | IFT172 | Intraflagellar transport 172. (1749 aa) |
| | ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) |
| | CER1 | Cerberus 1, DAN family BMP antagonist. (273 aa) |
| | DHRS3 | Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1036 aa) |
| | GLG1 | Golgi glycoprotein 1. (1169 aa) |
| | MEF2D | Myocyte enhancer factor 2D. (517 aa) |
| | COL13A1 | Collagen type XIII alpha 1 chain. (739 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | FAM20C | FAM20C golgi associated secretory pathway kinase. (507 aa) |
| | RANBP3L | RAN binding protein 3 like. (460 aa) |
| | RARB | Retinoic acid receptor beta. (396 aa) |
| | FOXN3 | Forkhead box N3. (457 aa) |
| | G3TG57_LOXAF | IlGF domain-containing protein. (118 aa) |
| | SH3PXD2B | SH3 and PX domains 2B. (883 aa) |
| | RARA | Retinoic acid receptor alpha. (464 aa) |
| | AMER1 | APC membrane recruitment protein 1. (1131 aa) |
| | COL3A1 | Collagen type III alpha 1 chain. (1470 aa) |
| | BGLAP | Osteocalcin; Binds strongly to apatite and calcium. (98 aa) |
| | MBTPS2 | Membrane bound transcription factor peptidase, site 2. (496 aa) |
| | MYOC | Myocilin. (506 aa) |
| | DYM | Dymeclin. (668 aa) |
| | NPPC | Natriuretic peptide C. (125 aa) |
| | ABI1 | Abl interactor 1. (481 aa) |
| | EPYC | Epiphycan. (322 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (465 aa) |
| | ANXA6 | Annexin. (673 aa) |
| | PPIB | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa) |
| | G3TLN2_LOXAF | Uncharacterized protein. (182 aa) |
| | PHOSPHO2 | Phosphatase, orphan 2. (241 aa) |
| | DLX5 | Distal-less homeobox 5. (289 aa) |
| | SPNS2 | Sphingolipid transporter 2. (470 aa) |
| | LTBP3 | Latent transforming growth factor beta binding protein 3. (1117 aa) |
| | SP5 | Sp5 transcription factor. (395 aa) |
| | SLC38A10 | Solute carrier family 38 member 10. (1032 aa) |
| | SFRP4 | Secreted frizzled related protein 4. (348 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa) |
| | PAX1 | Paired box 1. (453 aa) |
| | COMP | Cartilage oligomeric matrix protein. (638 aa) |
| | G3TS21_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (363 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (804 aa) |
| | IFITM5 | Interferon induced transmembrane protein 5. (135 aa) |
| | ADAMTS12 | Peptidase M12B domain-containing protein. (1163 aa) |
| | LRRC17 | Leucine rich repeat containing 17. (426 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa) |
| | G3TV42_LOXAF | Uncharacterized protein. (290 aa) |
| | CDX1 | Caudal type homeobox 1. (265 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa) |
| | G3TXA5_LOXAF | Pep_M12B_propep domain-containing protein. (163 aa) |
| | G3TXD8_LOXAF | Uncharacterized protein. (147 aa) |
| | AXIN2 | Axin 2. (820 aa) |
| | THPO | Thrombopoietin. (319 aa) |
| | P3H1 | Prolyl 3-hydroxylase 1. (736 aa) |
| | PLS3 | Plastin 3. (639 aa) |
| | ACTN3 | Actinin alpha 3 (gene/pseudogene). (902 aa) |
| | COL2A1 | Collagen type II alpha 1 chain. (1490 aa) |
| | NPR2 | Guanylate cyclase. (1047 aa) |
| | G3U6D1_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (364 aa) |
| | G3U6U6_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1605 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (253 aa) |
| | PHOSPHO1 | Phosphoethanolamine/phosphocholine phosphatase. (267 aa) |
| | NAB2 | NGFI-A binding protein 2. (426 aa) |
| | G3UAZ0_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (364 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (263 aa) |
| | VKORC1 | Vitamin K epoxide reductase complex subunit 1. (163 aa) |
| | CTC1 | CST telomere replication complex component 1. (1220 aa) |
| | G3UDE4_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (362 aa) |
| | ALPL | Alkaline phosphatase. (524 aa) |
| | COL1A1 | Collagen type I alpha 1 chain. (1455 aa) |
| | IFT80 | Intraflagellar transport 80. (778 aa) |
| | TMEM38B | Transmembrane protein 38B. (231 aa) |
| | MPIG6B | Megakaryocyte and platelet inhibitory receptor G6b. (242 aa) |
| | NOTUM | Notum, palmitoleoyl-protein carboxylesterase. (500 aa) |
| | TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (739 aa) |
| | RYR1 | Ryanodine receptor 1. (4982 aa) |
| | G3UHE5_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa) |
| | TTC9 | Tetratricopeptide repeat domain 9. (182 aa) |
| | G3UHY3_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (288 aa) |
| | TGM2 | Transglutaminase 2. (691 aa) |
| | G3UI57_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (360 aa) |
| | G3UIE1_LOXAF | Uncharacterized protein. (283 aa) |
| | G3UJ00_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (360 aa) |
| | ECM1 | Extracellular matrix protein 1. (558 aa) |
| | G3UK14_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (365 aa) |
| | GP1BA | Glycoprotein Ib platelet subunit alpha. (546 aa) |
| | G3ULT4_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa) |
| | G3UME9_LOXAF | Uncharacterized protein. (275 aa) |
| | FGF18 | Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (198 aa) |
| | GP9 | Glycoprotein IX platelet. (189 aa) |
| | MEGF8 | Uncharacterized protein. (424 aa) |
| | FOXP1 | Fork-head domain-containing protein. (683 aa) |
