STRINGSTRING
BAK1 BAK1 BCL2L11 BCL2L11 VDR VDR CRYAB CRYAB LRRC1 LRRC1 LEF1 LEF1 CCN1 CCN1 NOTCH1 NOTCH1 FGF4 FGF4 HAND2 HAND2 NKX2-5 NKX2-5 FOXC1 FOXC1 LRP5 LRP5 FOXC2 FOXC2 G3UJ64_LOXAF G3UJ64_LOXAF JAG2 JAG2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BAK1BCL2 antagonist/killer 1. (211 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (197 aa)
VDRVitamin D receptor. (424 aa)
CRYABCrystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (176 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
CCN1Cellular communication network factor 1. (383 aa)
NOTCH1Uncharacterized protein. (698 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
NKX2-5NK2 homeobox 5. (234 aa)
FOXC1Forkhead box C1. (559 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1605 aa)
FOXC2Forkhead box C2. (496 aa)
G3UJ64_LOXAFUncharacterized protein. (1460 aa)
JAG2Uncharacterized protein. (571 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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