(13 nodes) Dendritic spine morphogenesis network (Loxodonta africana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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co-expression

protein homology

Your Input:
	G3TU53_LOXAF	Uncharacterized protein. (821 aa)
	DOCK10	Dedicator of cytokinesis 10; Belongs to the DOCK family. (2044 aa)
	PRMT3	Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (449 aa)
	HDAC6	Histone deacetylase 6. (1122 aa)
	CDC42	Uncharacterized protein. (147 aa)
	EPHB2	EPH receptor B2. (978 aa)
	EPHB1	Uncharacterized protein. (716 aa)
	DIP2A	Disco interacting protein 2 homolog A. (1575 aa)
	DLG4	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
	EPHB3	EPH receptor B3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (881 aa)
	G3UGX7_LOXAF	Eph LBD domain-containing protein. (232 aa)
	SHANK3	ANK_REP_REGION domain-containing protein. (342 aa)
	WASL	WASP like actin nucleation promoting factor. (505 aa)

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	DLG4	ENSLAFP00000004873	ENSLAFP00000015624	Uncharacterized protein.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.433
CDC42	DOCK10	ENSLAFP00000004873	ENSLAFP00000018956	Uncharacterized protein.	Dedicator of cytokinesis 10; Belongs to the DOCK family.	0.917
CDC42	G3TU53_LOXAF	ENSLAFP00000004873	ENSLAFP00000019111	Uncharacterized protein.	Uncharacterized protein.	0.408
CDC42	SHANK3	ENSLAFP00000004873	ENSLAFP00000025180	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.422
CDC42	WASL	ENSLAFP00000004873	ENSLAFP00000021142	Uncharacterized protein.	WASP like actin nucleation promoting factor.	0.994
DLG4	CDC42	ENSLAFP00000015624	ENSLAFP00000004873	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Uncharacterized protein.	0.433
DLG4	G3TU53_LOXAF	ENSLAFP00000015624	ENSLAFP00000019111	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Uncharacterized protein.	0.843
DLG4	SHANK3	ENSLAFP00000015624	ENSLAFP00000025180	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	ANK_REP_REGION domain-containing protein.	0.857
DOCK10	CDC42	ENSLAFP00000018956	ENSLAFP00000004873	Dedicator of cytokinesis 10; Belongs to the DOCK family.	Uncharacterized protein.	0.917
EPHB1	G3UGX7_LOXAF	ENSLAFP00000011045	ENSLAFP00000027085	Uncharacterized protein.	Eph LBD domain-containing protein.	0.895
G3TU53_LOXAF	CDC42	ENSLAFP00000019111	ENSLAFP00000004873	Uncharacterized protein.	Uncharacterized protein.	0.408
G3TU53_LOXAF	DLG4	ENSLAFP00000019111	ENSLAFP00000015624	Uncharacterized protein.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.843
G3TU53_LOXAF	SHANK3	ENSLAFP00000019111	ENSLAFP00000025180	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.573
G3UGX7_LOXAF	EPHB1	ENSLAFP00000027085	ENSLAFP00000011045	Eph LBD domain-containing protein.	Uncharacterized protein.	0.895
SHANK3	CDC42	ENSLAFP00000025180	ENSLAFP00000004873	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.422
SHANK3	DLG4	ENSLAFP00000025180	ENSLAFP00000015624	ANK_REP_REGION domain-containing protein.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.857
SHANK3	G3TU53_LOXAF	ENSLAFP00000025180	ENSLAFP00000019111	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.573
WASL	CDC42	ENSLAFP00000021142	ENSLAFP00000004873	WASP like actin nucleation promoting factor.	Uncharacterized protein.	0.994

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