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| | LPCAT3 | Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa) |
| | G3SS82_LOXAF | Uncharacterized protein. (90 aa) |
| | NCOR2 | Nuclear receptor corepressor 2. (2467 aa) |
| | ATPSCKMT | ATP synthase c subunit lysine N-methyltransferase. (215 aa) |
| | DNAJC30 | DnaJ heat shock protein family (Hsp40) member C30. (186 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1087 aa) |
| | MAS1 | MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (295 aa) |
| | C1QTNF6 | C1q and TNF related 6. (271 aa) |
| | ACADM | Acyl-CoA dehydrogenase medium chain. (445 aa) |
| | INSIG2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) |
| | SORBS1 | Sorbin and SH3 domain containing 1. (1291 aa) |
| | ZBTB20 | Zinc finger and BTB domain containing 20. (743 aa) |
| | LCMT1 | Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (334 aa) |
| | SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (312 aa) |
| | SLC27A4 | Solute carrier family 27 member 4. (644 aa) |
| | STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa) |
| | TSPO | Translocator protein. (169 aa) |
| | SIK1 | Uncharacterized protein. (795 aa) |
| | PID1 | Phosphotyrosine interaction domain containing 1. (203 aa) |
| | RANBP2 | RAN binding protein 2. (3072 aa) |
| | RORA | RAR related orphan receptor A. (467 aa) |
| | GUCA1B | Guanylate cyclase activator 1B. (201 aa) |
| | LDLR | Low density lipoprotein receptor. (858 aa) |
| | CLN3 | Battenin. (436 aa) |
| | EP300 | E1A binding protein p300. (2420 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) |
| | ATCAY | ATCAY kinesin light chain interacting caytaxin. (350 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1208 aa) |
| | PLA2G3 | Phospholipase A2 group III. (494 aa) |
| | TFF3 | Trefoil factor 3. (81 aa) |
| | SLC35B4 | Solute carrier family 35 member B4. (331 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (796 aa) |
| | BMP6 | Bone morphogenetic protein 6. (298 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (468 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (836 aa) |
| | CDA | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa) |
| | TTC39B | Tetratricopeptide repeat domain 39B. (556 aa) |
| | GNMT | Glycine N-methyltransferase. (296 aa) |
| | LONP2 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (853 aa) |
| | IGFBP3 | Insulin like growth factor binding protein 3. (296 aa) |
| | G3TCM8_LOXAF | Uncharacterized protein. (212 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (662 aa) |
| | APOE | Apolipoprotein E. (314 aa) |
| | DAB2 | DAB adaptor protein 2. (768 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1854 aa) |
| | SPHK2 | Sphingosine kinase 2. (615 aa) |
| | FLCN | Folliculin. (578 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A. (470 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (801 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | G3TG57_LOXAF | IlGF domain-containing protein. (118 aa) |
| | LACC1 | Uncharacterized protein. (430 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (552 aa) |
| | DKKL1 | Dickkopf like acrosomal protein 1. (233 aa) |
| | ADCYAP1R1 | ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (497 aa) |
| | FMO2 | Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (270 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3. (626 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (342 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (744 aa) |
| | SLC7A11 | Solute carrier family 7 member 11. (503 aa) |
| | LPGAT1 | Lysophosphatidylglycerol acyltransferase 1. (385 aa) |
| | ABCG4 | ATP binding cassette subfamily G member 4. (645 aa) |
| | PPARD | Peroxisome proliferator activated receptor delta. (441 aa) |
| | CD74 | CD74 molecule. (280 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (796 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) |
| | HNF1A | HNF1 homeobox A. (631 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (300 aa) |
| | RD3 | Retinal degeneration 3, GUCY2D regulator. (197 aa) |
| | PRXL2C | Peroxiredoxin like 2C. (224 aa) |
| | ACADVL | Acyl-CoA dehydrogenase very long chain. (655 aa) |
| | CBFA2T3 | CBFA2/RUNX1 partner transcriptional co-repressor 3. (612 aa) |
| | PRMT3 | Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (449 aa) |
| | ERLIN1 | ER lipid raft associated 1. (350 aa) |
| | RORC | RAR related orphan receptor C. (517 aa) |
| | GCK | Phosphotransferase. (465 aa) |
| | ARL2 | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (184 aa) |
| | PLIN5 | Perilipin; Belongs to the perilipin family. (371 aa) |
| | BCKDK | Protein-serine/threonine kinase. (412 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (599 aa) |
| | BAD | BCL2 associated agonist of cell death. (206 aa) |
| | FMO1 | Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa) |
| | PDK3 | Protein-serine/threonine kinase. (415 aa) |
| | AVPR1B | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa) |
| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | ANKRD26 | Ankyrin repeat domain 26. (1604 aa) |
| | COX11 | Cytochrome c oxidase copper chaperone COX11. (275 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (409 aa) |
| | ARV1 | ARV1 homolog, fatty acid homeostasis modulator. (271 aa) |
| | IGFBP4 | Insulin like growth factor binding protein 4. (260 aa) |
| | STK11 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (439 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1140 aa) |
| | ERLIN2 | ER lipid raft associated 2. (339 aa) |
| | C1QTNF12 | C1q and TNF related 12. (308 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (840 aa) |
| | PDK4 | Protein-serine/threonine kinase. (412 aa) |
| | LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (631 aa) |
| | ERFE | Erythroferrone. (331 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | APOA5 | Apolipoprotein A5. (371 aa) |
| | NOS1 | Nitric oxide synthase 1. (1458 aa) |
| | FAM3C | Family with sequence similarity 3 member C. (227 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (973 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | SIRT1 | Sirtuin 1. (605 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (447 aa) |
| | APOB | Apolipoprotein B. (3100 aa) |
| | ANXA1 | Annexin. (348 aa) |
| | ABCG1 | ATP binding cassette subfamily G member 1. (666 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (486 aa) |
| | FMO5 | Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (730 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1461 aa) |
| | LOC100660588 | Dimethylaniline monooxygenase [N-oxide-forming]. (539 aa) |
| | FOXK2 | Forkhead box K2. (520 aa) |
| | NR1H2 | Nuclear receptor subfamily 1 group H member 2. (454 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (497 aa) |
| | AK4 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa) |
| | GUCA1A | Uncharacterized protein. (202 aa) |
| | ACMSD | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa) |
| | KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (802 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (974 aa) |
| | G3T0P7_LOXAF | Uncharacterized protein. (58 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1078 aa) |
| | GUCA2B | Guanylate cyclase activator 2B. (114 aa) |
| | GUCA2A | Guanylate cyclase activator 2A. (114 aa) |
| | SIRT5 | Sirtuin 5. (196 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa) |
| | VCP | Valosin containing protein; Belongs to the AAA ATPase family. (802 aa) |
| | SLC4A1 | Anion exchange protein. (904 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1199 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (358 aa) |
| | SEC14L5 | SEC14 like lipid binding 5. (633 aa) |
| | GCKR | Glucokinase regulator. (621 aa) |
| | STARD4 | StAR related lipid transfer domain containing 4. (209 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | KAT2B | Lysine acetyltransferase 2B. (755 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (503 aa) |
| | PPTC7 | Protein phosphatase; Belongs to the PP2C family. (305 aa) |
| | ABCB11 | ATP binding cassette subfamily B member 11. (1324 aa) |
| | COQ3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (325 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (677 aa) |
| | FMO4 | Dimethylaniline monooxygenase [N-oxide-forming]. (555 aa) |
| | SREBF2 | Sterol regulatory element binding transcription factor 2. (1109 aa) |
| | FH | Fumarate hydratase. (508 aa) |
| | DHCR7 | 7-dehydrocholesterol reductase. (475 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | SLC2A6 | Solute carrier family 2 member 6; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (507 aa) |
| | BEND3 | BEN domain containing 3. (828 aa) |
| | EPHX2 | Epoxide hydrolase 2. (558 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1011 aa) |
| | SEC14L3 | SEC14 like lipid binding 3. (400 aa) |
| | GIT1 | GIT ArfGAP 1. (770 aa) |
| | PDK1 | Protein-serine/threonine kinase. (389 aa) |
| | GIP | Gastric inhibitory polypeptide. (144 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (282 aa) |
| | NCS1 | Neuronal calcium sensor 1. (190 aa) |
| | PGP | Phosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily. (321 aa) |
| | DGKQ | Diacylglycerol kinase. (850 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (262 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (245 aa) |
| | LEPR | Leptin receptor. (835 aa) |
| | ABCD2 | ATP binding cassette subfamily D member 2. (742 aa) |
| | MST1 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (718 aa) |
| | APP | Amyloid beta precursor protein. (751 aa) |
| | G3TS21_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (363 aa) |
| | CLYBL | Citrate lyase beta like. (339 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (531 aa) |
| | SCAP | SREBF chaperone. (1285 aa) |
| | C1QTNF1 | C1q and TNF related 1. (290 aa) |
| | G3TUG9_LOXAF | Flavin-containing monooxygenase. (178 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | APOC2 | Apolipoprotein C2. (101 aa) |
| | G3TWY0_LOXAF | Uncharacterized protein. (88 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (185 aa) |
| | ETFBKMT | Electron transfer flavoprotein subunit beta lysine methyltransferase. (266 aa) |
| | CRY1 | Cryptochrome circadian regulator 1. (606 aa) |
| | CLCN2 | Chloride channel protein. (902 aa) |
| | PTH | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa) |
| | G3U1P0_LOXAF | Homeobox domain-containing protein. (160 aa) |
| | PDZD3 | PDZ domain containing 3. (503 aa) |
| | MID1IP1 | MID1 interacting protein 1. (183 aa) |
| | ACTN3 | Actinin alpha 3 (gene/pseudogene). (902 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (230 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (548 aa) |
| | SERPINA12 | Serpin family A member 12; Belongs to the serpin family. (413 aa) |
| | SIRT6 | Sirtuin 6. (336 aa) |
| | G3U6D1_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (364 aa) |
| | G3U6U6_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa) |
| | G3U7I1_LOXAF | Ig-like domain-containing protein. (396 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (611 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (440 aa) |
| | REST | RE1 silencing transcription factor. (1067 aa) |
| | ZNF692 | Uncharacterized protein. (137 aa) |
| | SESN2 | Sestrin 2. (485 aa) |
| | G3UA36_LOXAF | Uncharacterized protein. (403 aa) |
| | MALRD1 | Uncharacterized protein. (351 aa) |
| | DUSP12 | Dual specificity phosphatase 12. (338 aa) |
| | G3UAZ0_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (364 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (263 aa) |
| | FOXA2 | Forkhead box A2. (446 aa) |
| | SOGA1 | Suppressor of glucose, autophagy associated 1. (1472 aa) |
| | CLK2 | CDC like kinase 2; Belongs to the protein kinase superfamily. (500 aa) |
| | P2RY6 | Pyrimidinergic receptor P2Y6. (328 aa) |
| | STAT3 | Signal transducer and activator of transcription. (772 aa) |
| | G3UDE4_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (362 aa) |
| | C1QTNF3 | C1q domain-containing protein. (319 aa) |
| | FOXK1 | Forkhead box K1. (546 aa) |
| | EPM2AIP1 | EPM2A interacting protein 1. (606 aa) |
| | G3UEB2_LOXAF | Uncharacterized protein. (544 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1366 aa) |
| | TYSND1 | Trypsin domain containing 1. (455 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (739 aa) |
| | G3UHA8_LOXAF | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (430 aa) |
| | G3UHE5_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa) |
| | G3UHY3_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (288 aa) |
| | G3UI57_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (360 aa) |
| | G3UJ00_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (360 aa) |
| | FABP5 | Fatty acid binding protein 5. (134 aa) |
| | PDK2 | Protein-serine/threonine kinase. (362 aa) |
| | MLXIPL | MLX interacting protein like. (860 aa) |
| | G3UK14_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (365 aa) |
| | NCOR1 | Nuclear receptor corepressor 1. (2457 aa) |
| | TTC39A | Tetratricopeptide repeat domain 39A. (585 aa) |
| | SNAI1 | Snail family transcriptional repressor 1. (264 aa) |
| | G3ULQ3_LOXAF | Tyrosine-protein phosphatase non-receptor type. (369 aa) |
| | G3ULT4_LOXAF | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa) |
| | SIRT7 | Sirtuin 7. (329 aa) |
| | PLEK | Pleckstrin. (350 aa) |
