STRINGSTRING
G3U8D7_LOXAF G3U8D7_LOXAF ITGA4 ITGA4 THBS1 THBS1 RGCC RGCC PLCG1 PLCG1 CD40LG CD40LG CD160 CD160 GPER1 GPER1 FASLG FASLG ANO6 ANO6 PDCD4 PDCD4 CD248 CD248 CD40 CD40
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3U8D7_LOXAFUncharacterized protein. (202 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1033 aa)
THBS1Thrombospondin 1. (1169 aa)
RGCCRegulator of cell cycle. (137 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1220 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
CD160CD160 molecule. (187 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
FASLGTumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (277 aa)
ANO6Anoctamin. (821 aa)
PDCD4Programmed cell death 4. (470 aa)
CD248Uncharacterized protein. (278 aa)
CD40CD40 molecule. (260 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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