Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BARD1 | BRCA1 | ENSLAFP00000000460 | ENSLAFP00000012177 | BRCA1 associated RING domain 1. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.999 |
| BARD1 | G3T376_LOXAF | ENSLAFP00000000460 | ENSLAFP00000007672 | BRCA1 associated RING domain 1. | Uncharacterized protein. | 0.913 |
| BARD1 | G3UFC7_LOXAF | ENSLAFP00000000460 | ENSLAFP00000026535 | BRCA1 associated RING domain 1. | BRCT domain-containing protein. | 0.990 |
| BARD1 | LIG4 | ENSLAFP00000000460 | ENSLAFP00000024173 | BRCA1 associated RING domain 1. | DNA ligase. | 0.462 |
| BARD1 | MDC1 | ENSLAFP00000000460 | ENSLAFP00000014521 | BRCA1 associated RING domain 1. | Mediator of DNA damage checkpoint 1. | 0.760 |
| BARD1 | PAXIP1 | ENSLAFP00000000460 | ENSLAFP00000009639 | BRCA1 associated RING domain 1. | PAX interacting protein 1. | 0.760 |
| BARD1 | PES1 | ENSLAFP00000000460 | ENSLAFP00000017739 | BRCA1 associated RING domain 1. | Pescadillo ribosomal biogenesis factor 1. | 0.541 |
| BARD1 | RFC1 | ENSLAFP00000000460 | ENSLAFP00000009584 | BRCA1 associated RING domain 1. | Replication factor C subunit 1. | 0.592 |
| BARD1 | TOPBP1 | ENSLAFP00000000460 | ENSLAFP00000017954 | BRCA1 associated RING domain 1. | BRCT domain-containing protein. | 0.913 |
| BARD1 | TP53BP1 | ENSLAFP00000000460 | ENSLAFP00000001013 | BRCA1 associated RING domain 1. | Tumor protein p53 binding protein 1. | 0.824 |
| BRCA1 | BARD1 | ENSLAFP00000012177 | ENSLAFP00000000460 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | BRCA1 associated RING domain 1. | 0.999 |
| BRCA1 | CTDP1 | ENSLAFP00000012177 | ENSLAFP00000015612 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. | 0.432 |
| BRCA1 | G3T376_LOXAF | ENSLAFP00000012177 | ENSLAFP00000007672 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Uncharacterized protein. | 0.931 |
| BRCA1 | G3UFC7_LOXAF | ENSLAFP00000012177 | ENSLAFP00000026535 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | BRCT domain-containing protein. | 0.893 |
| BRCA1 | LIG4 | ENSLAFP00000012177 | ENSLAFP00000024173 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | DNA ligase. | 0.788 |
| BRCA1 | MDC1 | ENSLAFP00000012177 | ENSLAFP00000014521 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Mediator of DNA damage checkpoint 1. | 0.820 |
| BRCA1 | PARP1 | ENSLAFP00000012177 | ENSLAFP00000006575 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. | 0.678 |
| BRCA1 | PAXIP1 | ENSLAFP00000012177 | ENSLAFP00000009639 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | PAX interacting protein 1. | 0.808 |
| BRCA1 | RFC1 | ENSLAFP00000012177 | ENSLAFP00000009584 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Replication factor C subunit 1. | 0.536 |
| BRCA1 | TOPBP1 | ENSLAFP00000012177 | ENSLAFP00000017954 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | BRCT domain-containing protein. | 0.931 |
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