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KCNV1 KCNV1 CACNA1E CACNA1E SCN3A SCN3A KCND2 KCND2 CATSPER4 CATSPER4 CATSPER3 CATSPER3 TPCN2 TPCN2 TRPM2 TRPM2 CACNA1G CACNA1G KCNB1 KCNB1 RYR2 RYR2 SCN7A SCN7A CACNA1I CACNA1I HVCN1 HVCN1 SCN2A SCN2A KCNG4 KCNG4 KCNQ3 KCNQ3 ITPR2 ITPR2 NALCN NALCN KCNH5 KCNH5 TRPM8 TRPM8 TRPC7 TRPC7 HCN1 HCN1 KCNQ4 KCNQ4 G3U3A7_LOXAF G3U3A7_LOXAF TRPC4 TRPC4 KCNH8 KCNH8 KCNG2 KCNG2 KCNG3 KCNG3 CNGA2 CNGA2 HCN2 HCN2 CACNA1H CACNA1H KCNA4 KCNA4 ITPR1 ITPR1 SCN8A SCN8A KCNH3 KCNH3 KCNF1 KCNF1 TRPC1 TRPC1 TRPC3 TRPC3 KCNS1 KCNS1 KCNMA1 KCNMA1 HCN4 HCN4 KCNH2 KCNH2 SCN9A SCN9A TRPM4 TRPM4 KCNS3 KCNS3 KCNQ1 KCNQ1 CACNA1D CACNA1D TRPM5 TRPM5 SCN10A SCN10A TRPV4 TRPV4 ITPR3 ITPR3 CACNA1A CACNA1A TPCN1 TPCN1 TRPM7 TRPM7 KCNA3 KCNA3 HCN3 HCN3 SCN4A SCN4A CACNA1F CACNA1F TRPM3 TRPM3 KCNU1 KCNU1 KCNA2 KCNA2 G3TLJ8_LOXAF G3TLJ8_LOXAF G3TKX7_LOXAF G3TKX7_LOXAF KCNH4 KCNH4 CNGA3 CNGA3 KCNC4 KCNC4 CACNA1B CACNA1B KCNA5 KCNA5 RYR3 RYR3 KCNQ2 KCNQ2 TRPM1 TRPM1 KCNC1 KCNC1 TRPC5 TRPC5 CACNA1C CACNA1C KCNV2 KCNV2 CNGA4 CNGA4 TRPC6 TRPC6 KCND3 KCND3 CACNA1S CACNA1S CNGA1 CNGA1 KCNA1 KCNA1 KCNA7 KCNA7 RYR1 RYR1 KCNC2 KCNC2 G3UIJ0_LOXAF G3UIJ0_LOXAF TRPV1 TRPV1 TRPV3 TRPV3 TRPV2 TRPV2 KCNG1 KCNG1 KCNH1 KCNH1 CATSPER2 CATSPER2 KCNH6 KCNH6 TRPA1 TRPA1 KCND1 KCND1 SCN1A SCN1A KCNH7 KCNH7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNV1Potassium voltage-gated channel modifier subfamily V member 1; Belongs to the potassium channel family. (504 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (1900 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2006 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (372 aa)
CATSPER4Cation channel sperm associated 4. (367 aa)
CATSPER3Cation channel sperm associated 3. (375 aa)
TPCN2Ion_trans domain-containing protein. (456 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1500 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2380 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
RYR2Ryanodine receptor 2. (4951 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1931 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2151 aa)
HVCN1Hydrogen voltage gated channel 1. (263 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2006 aa)
KCNG4Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family. (498 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (743 aa)
ITPR2Ion_trans domain-containing protein. (495 aa)
NALCNUncharacterized protein. (1210 aa)
KCNH5Potassium voltage-gated channel subfamily H member 5. (988 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1108 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (878 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (526 aa)
G3U3A7_LOXAFIon_trans domain-containing protein. (385 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (978 aa)
KCNH8Potassium voltage-gated channel subfamily H member 8. (687 aa)
KCNG2Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (362 aa)
KCNG3Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family. (229 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (662 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (732 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (1763 aa)
KCNA4Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (638 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2700 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1991 aa)
KCNH3Potassium voltage-gated channel subfamily H member 3. (1076 aa)
KCNF1Potassium voltage-gated channel modifier subfamily F member 1; Belongs to the potassium channel family. (494 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (744 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (849 aa)
KCNS1Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family. (492 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1077 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1026 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1054 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1987 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1139 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
KCNQ1Ion_trans domain-containing protein; Belongs to the potassium channel family. (332 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2163 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1140 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (739 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2670 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2036 aa)
TPCN1Two pore segment channel 1. (822 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1873 aa)
KCNA3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (526 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (692 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1904 aa)
CACNA1FCalcium voltage-gated channel subunit alpha1 F. (1829 aa)
TRPM3Transient receptor potential cation channel subfamily M member 3. (1663 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1022 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
G3TLJ8_LOXAFUncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (1257 aa)
G3TKX7_LOXAFIon_trans domain-containing protein. (402 aa)
KCNH4Potassium voltage-gated channel subfamily H member 4. (1009 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (669 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (624 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2356 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (602 aa)
RYR3Ryanodine receptor 3. (4470 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (739 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1605 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (582 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2004 aa)
KCNV2Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family. (552 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (500 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (929 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (369 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1685 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (687 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
KCNA7Ion_trans domain-containing protein; Belongs to the potassium channel family. (123 aa)
RYR1Ryanodine receptor 1. (4982 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (410 aa)
G3UIJ0_LOXAFIon_trans domain-containing protein. (665 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (840 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (757 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (516 aa)
KCNH1Uncharacterized protein. (989 aa)
CATSPER2Cation channel sperm associated 2. (397 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (957 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1118 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (648 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2009 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1098 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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