(30 nodes) Spectrin/alpha-actinin network (Loxodonta africana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3U6K7_LOXAF	PH domain-containing protein. (1231 aa)
	MCF2L2	CRAL-TRIO domain-containing protein. (390 aa)
	ACTN1	Actinin alpha 1. (892 aa)
	AKAP6	A-kinase anchoring protein 6. (2304 aa)
	PLEC	Plectin. (4441 aa)
	SYNE3	Spectrin repeat containing nuclear envelope family member 3. (975 aa)
	UTRN	Utrophin. (3097 aa)
	DRP2	Dystrophin related protein 2. (955 aa)
	SPTB	Spectrin beta chain; Belongs to the spectrin family. (2329 aa)
	TRIO	Trio Rho guanine nucleotide exchange factor. (3038 aa)
	SYNE1	Spectrin repeat containing nuclear envelope protein 1. (8799 aa)
	MACF1	Microtubule actin crosslinking factor 1. (7373 aa)
	SPTBN1	Spectrin beta chain; Belongs to the spectrin family. (2364 aa)
	SPTA1	Spectrin alpha, erythrocytic 1. (2392 aa)
	G3TA05_LOXAF	Uncharacterized protein. (565 aa)
	G3TAJ4_LOXAF	Uncharacterized protein. (2013 aa)
	ACTN2	Actinin alpha 2. (896 aa)
	MCF2	MCF.2 cell line derived transforming sequence. (964 aa)
	EVPL	SH3 domain-containing protein. (1970 aa)
	SYNE2	KASH domain-containing protein. (2115 aa)
	DSP	Desmoplakin. (2870 aa)
	G3TRN6_LOXAF	Uncharacterized protein. (314 aa)
	ACTN4	Actinin alpha 4. (898 aa)
	PPL	Periplakin. (1755 aa)
	CCDC141	Coiled-coil domain containing 141. (655 aa)
	ACTN3	Actinin alpha 3 (gene/pseudogene). (902 aa)
	DST	Uncharacterized protein. (5128 aa)
	SPTBN2	Spectrin beta chain; Belongs to the spectrin family. (2393 aa)
	SPTAN1	Spectrin alpha, non-erythrocytic 1. (2478 aa)
	MCF2L	MCF.2 cell line derived transforming sequence like. (1160 aa)

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN1	G3U6K7_LOXAF	ENSLAFP00000000587	ENSLAFP00000023465	Actinin alpha 1.	PH domain-containing protein.	0.784
ACTN2	ACTN3	ENSLAFP00000011919	ENSLAFP00000022606	Actinin alpha 2.	Actinin alpha 3 (gene/pseudogene).	0.945
ACTN2	CCDC141	ENSLAFP00000011919	ENSLAFP00000020703	Actinin alpha 2.	Coiled-coil domain containing 141.	0.400
ACTN2	G3U6K7_LOXAF	ENSLAFP00000011919	ENSLAFP00000023465	Actinin alpha 2.	PH domain-containing protein.	0.760
ACTN3	ACTN2	ENSLAFP00000022606	ENSLAFP00000011919	Actinin alpha 3 (gene/pseudogene).	Actinin alpha 2.	0.945
ACTN3	CCDC141	ENSLAFP00000022606	ENSLAFP00000020703	Actinin alpha 3 (gene/pseudogene).	Coiled-coil domain containing 141.	0.400
ACTN3	G3U6K7_LOXAF	ENSLAFP00000022606	ENSLAFP00000023465	Actinin alpha 3 (gene/pseudogene).	PH domain-containing protein.	0.731
ACTN4	G3U6K7_LOXAF	ENSLAFP00000019301	ENSLAFP00000023465	Actinin alpha 4.	PH domain-containing protein.	0.810
CCDC141	ACTN2	ENSLAFP00000020703	ENSLAFP00000011919	Coiled-coil domain containing 141.	Actinin alpha 2.	0.400
CCDC141	ACTN3	ENSLAFP00000020703	ENSLAFP00000022606	Coiled-coil domain containing 141.	Actinin alpha 3 (gene/pseudogene).	0.400
DRP2	G3TA05_LOXAF	ENSLAFP00000005826	ENSLAFP00000010660	Dystrophin related protein 2.	Uncharacterized protein.	0.907
DSP	DST	ENSLAFP00000018163	ENSLAFP00000024759	Desmoplakin.	Uncharacterized protein.	0.404
DSP	MACF1	ENSLAFP00000018163	ENSLAFP00000009667	Desmoplakin.	Microtubule actin crosslinking factor 1.	0.404
DSP	SPTAN1	ENSLAFP00000018163	ENSLAFP00000025173	Desmoplakin.	Spectrin alpha, non-erythrocytic 1.	0.486
DST	DSP	ENSLAFP00000024759	ENSLAFP00000018163	Uncharacterized protein.	Desmoplakin.	0.404
DST	PLEC	ENSLAFP00000024759	ENSLAFP00000002516	Uncharacterized protein.	Plectin.	0.404
DST	SPTAN1	ENSLAFP00000024759	ENSLAFP00000025173	Uncharacterized protein.	Spectrin alpha, non-erythrocytic 1.	0.495
EVPL	PPL	ENSLAFP00000014539	ENSLAFP00000019316	SH3 domain-containing protein.	Periplakin.	0.906
EVPL	SPTAN1	ENSLAFP00000014539	ENSLAFP00000025173	SH3 domain-containing protein.	Spectrin alpha, non-erythrocytic 1.	0.450
G3TA05_LOXAF	DRP2	ENSLAFP00000010660	ENSLAFP00000005826	Uncharacterized protein.	Dystrophin related protein 2.	0.907

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