STRINGSTRING
PIK3C2B PIK3C2B FER1L6 FER1L6 TOLLIP TOLLIP DOC2B DOC2B DOCK4 DOCK4 UVRAG UVRAG CPNE7 CPNE7 INPP4A INPP4A PLCL1 PLCL1 SYDE2 SYDE2 MCTP1 MCTP1 PIK3CB PIK3CB SNRNP200 SNRNP200 RPGRIP1L RPGRIP1L TNS3 TNS3 PLCL2 PLCL2 BCR BCR TC2N TC2N G3TDZ7_LOXAF G3TDZ7_LOXAF ESYT1 ESYT1 PIK3C2G PIK3C2G RASAL1 RASAL1 WWP2 WWP2 SYT1 SYT1 SYT12 SYT12 PLA2G4B PLA2G4B CPNE2 CPNE2 DOCK3 DOCK3 SYT8 SYT8 PLCD4 PLCD4 CPNE4 CPNE4 CPNE3 CPNE3 RIMS4 RIMS4 HECW2 HECW2 GAK GAK PLCB2 PLCB2 ITCH ITCH PRF1 PRF1 ASCC3 ASCC3 NEDD4L NEDD4L RASA1 RASA1 PKN2 PKN2 ESYT3 ESYT3 CC2D1A CC2D1A DOCK8 DOCK8 CEP120 CEP120 RIMS3 RIMS3 SYT4 SYT4 RIMS2 RIMS2 TNS2 TNS2 RPGRIP1 RPGRIP1 SYTL3 SYTL3 PLCB3 PLCB3 G3T2U8_LOXAF G3T2U8_LOXAF C2CD2 C2CD2 CC2D1B CC2D1B MCTP2 MCTP2 DAB2IP DAB2IP G3T0V1_LOXAF G3T0V1_LOXAF SYNGAP1 SYNGAP1 G3T030_LOXAF G3T030_LOXAF WWC2 WWC2 BAIAP3 BAIAP3 DOCK2 DOCK2 PLCB4 PLCB4 SYTL4 SYTL4 SYT10 SYT10 DOCK9 DOCK9 PRKCA PRKCA CPNE8 CPNE8 CAPN6 CAPN6 RPH3A RPH3A SYT9 SYT9 PCLO PCLO PTEN PTEN SYT14 SYT14 PLA2G4E PLA2G4E CC2D2A CC2D2A RASA2 RASA2 DOC2A DOC2A PIK3CG PIK3CG SMURF2 SMURF2 PLCG1 PLCG1 RAB11FIP1 RAB11FIP1 PLA2G4F PLA2G4F PLA2G4D PLA2G4D WWP1 WWP1 PIK3C2A PIK3C2A DOCK5 DOCK5 SYT5 SYT5 ABR ABR PKN3 PKN3 DOCK6 DOCK6 SYTL1 SYTL1 SYTL2 SYTL2 SYT6 SYT6 G3UF18_LOXAF G3UF18_LOXAF PKN1 PKN1 SYT7 SYT7 SMURF1 SMURF1 FER1L5 FER1L5 MYOF MYOF PLCD3 PLCD3 G3U8E3_LOXAF G3U8E3_LOXAF PLCH2 PLCH2 G3U6J9_LOXAF G3U6J9_LOXAF G3U5L2_LOXAF G3U5L2_LOXAF PLCD1 PLCD1 PRKCH PRKCH UNC13C UNC13C UNC13D UNC13D DYSF DYSF ITSN1 ITSN1 PRKCG PRKCG UNC13B UNC13B G3U095_LOXAF G3U095_LOXAF WWC1 WWC1 RAB11FIP5 RAB11FIP5 OTOF OTOF PIK3C3 PIK3C3 NEDD4 NEDD4 AIDA AIDA DOCK1 DOCK1 PIK3CA PIK3CA RAB11FIP2 RAB11FIP2 PLCB1 PLCB1 DOCK11 DOCK11 DOCK7 DOCK7 CAPN5 CAPN5 PLCG2 PLCG2 PLCE1 PLCE1 PRKCQ PRKCQ RASAL2 RASAL2 PIK3CD PIK3CD ESYT2 ESYT2 PLA2G4A PLA2G4A PLCH1 PLCH1 PRKCB PRKCB TNS1 TNS1 CPNE5 CPNE5 SYT13 SYT13 SEC63 SEC63 SYT2 SYT2 RASA3 RASA3 SYT16 SYT16 C2CD2L C2CD2L SYT3 SYT3 C2CD5 C2CD5 CPNE6 CPNE6 G3TRH8_LOXAF G3TRH8_LOXAF G3TRL7_LOXAF G3TRL7_LOXAF G3TRR6_LOXAF G3TRR6_LOXAF WWC3 WWC3 G3TRX3_LOXAF G3TRX3_LOXAF CPNE1 CPNE1 DOCK10 DOCK10 DNAJC6 DNAJC6 SYT11 SYT11 PRKCD PRKCD G3TWP0_LOXAF G3TWP0_LOXAF INPP4B INPP4B SYT17 SYT17
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1633 aa)
FER1L6Fer-1 like family member 6. (1753 aa)
TOLLIPToll interacting protein. (274 aa)
DOC2BDouble C2-like domain-containing protein. (412 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1973 aa)
UVRAGC2 domain-containing protein. (369 aa)
CPNE7Copine 7. (558 aa)
INPP4AInositol polyphosphate-4-phosphatase type I A. (939 aa)
PLCL1Phosphoinositide phospholipase C. (1017 aa)
SYDE2Synapse defective Rho GTPase homolog 2. (1105 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (701 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa)
RPGRIP1LRPGRIP1 like. (1270 aa)
TNS3Tensin 3. (1448 aa)
PLCL2Phosphoinositide phospholipase C. (1128 aa)
BCRBCR activator of RhoGEF and GTPase. (1250 aa)
TC2NTandem C2 domains, nuclear. (488 aa)
G3TDZ7_LOXAFUncharacterized protein. (542 aa)
ESYT1Extended synaptotagmin 1. (1070 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1507 aa)
RASAL1RAS protein activator like 1. (803 aa)
WWP2E3 ubiquitin-protein ligase. (870 aa)
SYT1Synaptotagmin 1. (422 aa)
SYT12Synaptotagmin 12. (421 aa)
PLA2G4BPhospholipase A2. (776 aa)
CPNE2Copine 2. (520 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (2018 aa)
SYT8Synaptotagmin 8. (400 aa)
PLCD4Phosphoinositide phospholipase C. (763 aa)
CPNE4Copine 4. (557 aa)
CPNE3Copine 3. (531 aa)
RIMS4Regulating synaptic membrane exocytosis 4. (235 aa)
HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1568 aa)
GAKCyclin G associated kinase. (1113 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
ITCHE3 ubiquitin-protein ligase. (865 aa)
PRF1Perforin 1. (555 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (1855 aa)
NEDD4LE3 ubiquitin-protein ligase. (940 aa)
RASA1RAS p21 protein activator 1. (1043 aa)
PKN2Protein kinase N2. (971 aa)
ESYT3Extended synaptotagmin 3. (894 aa)
CC2D1ACoiled-coil and C2 domain containing 1A. (944 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2101 aa)
CEP120Centrosomal protein 120. (985 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (309 aa)
SYT4Synaptotagmin 4. (428 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1077 aa)
TNS2Tensin 2. (1409 aa)
RPGRIP1RPGR interacting protein 1. (1293 aa)
SYTL3Synaptotagmin like 3. (608 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1202 aa)
G3T2U8_LOXAFUncharacterized protein. (1357 aa)
C2CD2C2 calcium dependent domain containing 2. (712 aa)
CC2D1BCoiled-coil and C2 domain containing 1B. (855 aa)
MCTP2Multiple C2 and transmembrane domain containing 2. (879 aa)
DAB2IPDAB2 interacting protein. (1189 aa)
G3T0V1_LOXAFUncharacterized protein. (274 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1067 aa)
G3T030_LOXAFUncharacterized protein. (796 aa)
WWC2WW and C2 domain containing 2. (1150 aa)
BAIAP3BAI1 associated protein 3. (930 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1830 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1175 aa)
SYTL4Synaptotagmin like 4. (672 aa)
SYT10Synaptotagmin 10. (522 aa)
DOCK9Dedicator of cytokinesis 9; Belongs to the DOCK family. (2077 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
CPNE8Copine 8. (577 aa)
CAPN6Calpain 6; Belongs to the peptidase C2 family. (644 aa)
RPH3ARabphilin 3A. (613 aa)
SYT9Synaptotagmin 9. (491 aa)
PCLOPiccolo presynaptic cytomatrix protein. (4746 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
SYT14Synaptotagmin 14. (536 aa)
PLA2G4EPhospholipase A2. (809 aa)
CC2D2ACoiled-coil and C2 domain containing 2A. (1632 aa)
RASA2RAS p21 protein activator 2. (804 aa)
DOC2ADouble C2-like domain-containing protein. (401 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1112 aa)
SMURF2E3 ubiquitin-protein ligase. (732 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1220 aa)
RAB11FIP1FIP-RBD domain-containing protein. (650 aa)
PLA2G4FPhospholipase A2. (852 aa)
PLA2G4DPhospholipase A2. (798 aa)
WWP1E3 ubiquitin-protein ligase. (923 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1693 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1855 aa)
SYT5Synaptotagmin 5. (386 aa)
ABRABR activator of RhoGEF and GTPase. (871 aa)
PKN3Protein kinase N3. (940 aa)
DOCK6Dedicator of cytokinesis 6; Belongs to the DOCK family. (2107 aa)
SYTL1Synaptotagmin like 1. (585 aa)
SYTL2Synaptotagmin like 2. (951 aa)
SYT6Synaptotagmin 6. (503 aa)
G3UF18_LOXAFC2 domain-containing protein. (289 aa)
PKN1Protein kinase N1. (933 aa)
SYT7Synaptotagmin 7. (576 aa)
SMURF1E3 ubiquitin-protein ligase. (740 aa)
FER1L5Fer-1 like family member 5. (1522 aa)
MYOFMyoferlin. (2044 aa)
PLCD3Phosphoinositide phospholipase C. (745 aa)
G3U8E3_LOXAFUncharacterized protein. (704 aa)
PLCH2Phosphoinositide phospholipase C. (1419 aa)
G3U6J9_LOXAFUncharacterized protein. (1979 aa)
G3U5L2_LOXAFC2 domain-containing protein. (375 aa)
PLCD1Phosphoinositide phospholipase C. (751 aa)
PRKCHC2 domain-containing protein. (122 aa)
UNC13CUncharacterized protein. (1413 aa)
UNC13DUnc-13 homolog D. (1083 aa)
DYSFDysferlin. (1489 aa)
ITSN1Intersectin 1. (1719 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (693 aa)
UNC13BUnc-13 homolog B. (1989 aa)
G3U095_LOXAFUncharacterized protein. (367 aa)
WWC1WW and C2 domain containing 1. (1129 aa)
RAB11FIP5Uncharacterized protein. (1277 aa)
OTOFOtoferlin. (1950 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (890 aa)
NEDD4E3 ubiquitin-protein ligase. (845 aa)
AIDAUncharacterized protein. (306 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1863 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RAB11FIP2RAB11 family interacting protein 2. (506 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1089 aa)
DOCK11Dedicator of cytokinesis 11; Belongs to the DOCK family. (2040 aa)
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2135 aa)
CAPN5Calpain 5; Belongs to the peptidase C2 family. (636 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PLCE1Phosphoinositide phospholipase C. (1887 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
RASAL2RAS protein activator like 2. (1213 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1038 aa)
ESYT2Extended synaptotagmin 2. (845 aa)
PLA2G4APhospholipase A2. (748 aa)
PLCH1Phosphoinositide phospholipase C. (1674 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
TNS1Tensin 1. (1747 aa)
CPNE5Copine 5. (594 aa)
SYT13Synaptotagmin 13. (422 aa)
SEC63SEC63 homolog, protein translocation regulator. (760 aa)
SYT2Synaptotagmin 2. (419 aa)
RASA3RAS p21 protein activator 3. (834 aa)
SYT16Synaptotagmin 16. (631 aa)
C2CD2LC2CD2 like. (715 aa)
SYT3Synaptotagmin 3. (542 aa)
C2CD5C2 calcium dependent domain containing 5. (1017 aa)
CPNE6Copine 6. (557 aa)
G3TRH8_LOXAFUncharacterized protein. (422 aa)
G3TRL7_LOXAFC2 domain-containing protein. (125 aa)
G3TRR6_LOXAFUncharacterized protein. (486 aa)
WWC3WWC family member 3. (1140 aa)
G3TRX3_LOXAFUncharacterized protein. (240 aa)
CPNE1Copine 1. (537 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2044 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (957 aa)
SYT11Synaptotagmin 11. (432 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (701 aa)
G3TWP0_LOXAFSEC63 domain-containing protein. (275 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (939 aa)
SYT17Synaptotagmin 17. (472 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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