(7 nodes) Insulin-like superfamily network (Loxodonta africana)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Your Input:
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
	IGF2	Insulin like growth factor 2. (175 aa)
	INSL6	IlGF domain-containing protein. (197 aa)
	INSL5	Uncharacterized protein. (58 aa)
	G3TG57_LOXAF	IlGF domain-containing protein. (118 aa)
	INSL3	IlGF domain-containing protein. (133 aa)
	G3TIV5_LOXAF	IlGF domain-containing protein. (158 aa)

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3TG57_LOXAF	IGF2	ENSLAFP00000013434	ENSLAFP00000009448	IlGF domain-containing protein.	Insulin like growth factor 2.	0.769
G3TG57_LOXAF	INS	ENSLAFP00000013434	ENSLAFP00000015739	IlGF domain-containing protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.648
G3TIV5_LOXAF	INSL3	ENSLAFP00000014604	ENSLAFP00000022371	IlGF domain-containing protein.	IlGF domain-containing protein.	0.974
G3TIV5_LOXAF	INSL5	ENSLAFP00000014604	ENSLAFP00000013266	IlGF domain-containing protein.	Uncharacterized protein.	0.941
G3TIV5_LOXAF	INSL6	ENSLAFP00000014604	ENSLAFP00000006288	IlGF domain-containing protein.	IlGF domain-containing protein.	0.467
IGF2	G3TG57_LOXAF	ENSLAFP00000009448	ENSLAFP00000013434	Insulin like growth factor 2.	IlGF domain-containing protein.	0.769
IGF2	INS	ENSLAFP00000009448	ENSLAFP00000015739	Insulin like growth factor 2.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.554
INS	G3TG57_LOXAF	ENSLAFP00000015739	ENSLAFP00000013434	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	IlGF domain-containing protein.	0.648
INS	IGF2	ENSLAFP00000015739	ENSLAFP00000009448	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin like growth factor 2.	0.554
INSL3	G3TIV5_LOXAF	ENSLAFP00000022371	ENSLAFP00000014604	IlGF domain-containing protein.	IlGF domain-containing protein.	0.974
INSL3	INSL5	ENSLAFP00000022371	ENSLAFP00000013266	IlGF domain-containing protein.	Uncharacterized protein.	0.924
INSL5	G3TIV5_LOXAF	ENSLAFP00000013266	ENSLAFP00000014604	Uncharacterized protein.	IlGF domain-containing protein.	0.941
INSL5	INSL3	ENSLAFP00000013266	ENSLAFP00000022371	Uncharacterized protein.	IlGF domain-containing protein.	0.924
INSL5	INSL6	ENSLAFP00000013266	ENSLAFP00000006288	Uncharacterized protein.	IlGF domain-containing protein.	0.446
INSL6	G3TIV5_LOXAF	ENSLAFP00000006288	ENSLAFP00000014604	IlGF domain-containing protein.	IlGF domain-containing protein.	0.467
INSL6	INSL5	ENSLAFP00000006288	ENSLAFP00000013266	IlGF domain-containing protein.	Uncharacterized protein.	0.446

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