STRINGSTRING
SUZ12 SUZ12 AEBP2 AEBP2 DPY30 DPY30 ENSLAFP00000027938 ENSLAFP00000027938 SETD7 SETD7 RBBP5 RBBP5 ENSLAFP00000016306 ENSLAFP00000016306 SUV39H2 SUV39H2 SETD1A SETD1A G3TS46_LOXAF G3TS46_LOXAF ENSLAFP00000018530 ENSLAFP00000018530 SETD1B SETD1B ATF7IP ATF7IP H4C11 H4C11 EED EED NSD3 NSD3 EZH2 EZH2 ASH2L ASH2L ASH1L ASH1L G3U0S4_LOXAF G3U0S4_LOXAF WDR5B WDR5B SMYD4 SMYD4 ATF7IP2 ATF7IP2 PHF11 PHF11 SMYD2 SMYD2 RBBP7 RBBP7 KMT5A KMT5A SETDB2 SETDB2 RBBP4 RBBP4 SETD2 SETD2 SETDB1 SETDB1 LOC100661536 LOC100661536 G3UKU6_LOXAF G3UKU6_LOXAF DOT1L DOT1L KMT2A KMT2A ENSLAFP00000028190 ENSLAFP00000028190 ENSLAFP00000027955 ENSLAFP00000027955 CCDC153 CCDC153 EHMT1 EHMT1 MECOM MECOM G3U1Z3_LOXAF G3U1Z3_LOXAF ENSLAFP00000022732 ENSLAFP00000022732 ENSLAFP00000022963 ENSLAFP00000022963 PHF7 PHF7 G2E3 G2E3 NSD1 NSD1 LOC111752376 LOC111752376 SUV39H1 SUV39H1 KMT2E KMT2E SETD6 SETD6 RELA RELA PRDM16 PRDM16 WDR5 WDR5 EZH1 EZH1 G3T5C6_LOXAF G3T5C6_LOXAF KMT2D KMT2D G3T476_LOXAF G3T476_LOXAF SMYD5 SMYD5 NFKB1 NFKB1 EHMT2 EHMT2 NSD2 NSD2 KMT2C KMT2C SMYD1 SMYD1 NFKB2 NFKB2 KMT5B KMT5B G3U8T3_LOXAF G3U8T3_LOXAF G3U9V5_LOXAF G3U9V5_LOXAF PHF6 PHF6 G3UF27_LOXAF G3UF27_LOXAF G3UFS4_LOXAF G3UFS4_LOXAF SETD3 SETD3 KMT2B KMT2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)
AEBP2AE binding protein 2. (494 aa)
DPY30Dpy-30 histone methyltransferase complex regulatory subunit. (99 aa)
ENSLAFP00000027938annotation not available (103 aa)
SETD7Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes. (366 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (541 aa)
ENSLAFP00000016306annotation not available (103 aa)
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (403 aa)
SETD1ASET domain containing 1A, histone lysine methyltransferase. (1691 aa)
G3TS46_LOXAFUncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (124 aa)
ENSLAFP00000018530annotation not available (103 aa)
SETD1BSET domain containing 1B, histone lysine methyltransferase. (1772 aa)
ATF7IPActivating transcription factor 7 interacting protein. (1259 aa)
H4C11H4 clustered histone 11. (103 aa)
EEDEmbryonic ectoderm development. (510 aa)
NSD3Nuclear receptor binding SET domain protein 3. (1443 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (628 aa)
ASH1LASH1 like histone lysine methyltransferase. (1974 aa)
G3U0S4_LOXAFUncharacterized protein. (1523 aa)
WDR5BWD repeat domain 5B. (330 aa)
SMYD4SET and MYND domain containing 4. (717 aa)
ATF7IP2Activating transcription factor 7 interacting protein 2. (691 aa)
PHF11PHD finger protein 11. (298 aa)
SMYD2SET and MYND domain containing 2. (430 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (426 aa)
KMT5ALysine methyltransferase 5A. (317 aa)
SETDB2SET domain bifurcated histone lysine methyltransferase 2. (711 aa)
RBBP4RB binding protein 4, chromatin remodeling factor. (425 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (1941 aa)
SETDB1SET domain bifurcated histone lysine methyltransferase 1. (1307 aa)
LOC100661536Uncharacterized protein. (307 aa)
G3UKU6_LOXAFHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (104 aa)
DOT1LHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1546 aa)
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3964 aa)
ENSLAFP00000028190annotation not available (104 aa)
ENSLAFP00000027955annotation not available (103 aa)
CCDC153Coiled-coil domain containing 153. (201 aa)
EHMT1Euchromatic histone lysine methyltransferase 1. (846 aa)
MECOMMDS1 and EVI1 complex locus. (1042 aa)
G3U1Z3_LOXAFHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (104 aa)
ENSLAFP00000022732annotation not available (103 aa)
ENSLAFP00000022963annotation not available (103 aa)
PHF7PHD finger protein 7. (382 aa)
G2E3G2/M-phase specific E3 ubiquitin protein ligase. (718 aa)
NSD1Nuclear receptor binding SET domain protein 1. (2348 aa)
LOC111752376Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (364 aa)
KMT2ELysine methyltransferase 2E. (1835 aa)
SETD6N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. (476 aa)
RELARELA proto-oncogene, NF-kB subunit. (555 aa)
PRDM16PR/SET domain 16. (1270 aa)
WDR5WD repeat domain 5. (350 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (747 aa)
G3T5C6_LOXAFUncharacterized protein. (127 aa)
KMT2DLysine methyltransferase 2D. (4936 aa)
G3T476_LOXAFUncharacterized protein. (131 aa)
SMYD5SMYD family member 5. (417 aa)
NFKB1Nuclear factor kappa B subunit 1. (973 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1225 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1361 aa)
KMT2CUncharacterized protein. (2177 aa)
SMYD1SET and MYND domain containing 1. (445 aa)
NFKB2Nuclear factor kappa B subunit 2. (896 aa)
KMT5BLysine methyltransferase 5B. (883 aa)
G3U8T3_LOXAFHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (104 aa)
G3U9V5_LOXAFHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (105 aa)
PHF6PHD finger protein 6. (450 aa)
G3UF27_LOXAFSET domain-containing protein. (338 aa)
G3UFS4_LOXAFUncharacterized protein. (259 aa)
SETD3Protein-histidine N-methyltransferase. (598 aa)
KMT2BLysine methyltransferase 2B. (2303 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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