STRINGSTRING
SETD6 SETD6 DMAP1 DMAP1 BRD1 BRD1 CHD3 CHD3 SMARCD1 SMARCD1 ELP1 ELP1 ELP5 ELP5 JADE1 JADE1 JADE2 JADE2 PRDM16 PRDM16 SUDS3 SUDS3 SMARCA4 SMARCA4 H2AC21 H2AC21 KDM3B KDM3B EZH2 EZH2 ASH2L ASH2L ASH1L ASH1L SAP30L SAP30L RBBP4 RBBP4 ATF7 ATF7 GATAD2B GATAD2B BRWD3 BRWD3 SAP30 SAP30 KAT7 KAT7 PRMT7 PRMT7 MCRS1 MCRS1 ENY2 ENY2 SETD2 SETD2 PHF21A PHF21A PRMT8 PRMT8 HCFC2 HCFC2 TEX30 TEX30 LOC100661012 LOC100661012 SETDB1 SETDB1 KMT2E KMT2E ARID2 ARID2 CARM1 CARM1 HIST1H2BA HIST1H2BA KDM1B KDM1B TMEM62 TMEM62 RPS2 RPS2 WDR77 WDR77 MTA3 MTA3 PRMT5 PRMT5 HDAC1 HDAC1 SUPT3H SUPT3H SUV39H1 SUV39H1 LOC111752376 LOC111752376 LOC100662145 LOC100662145 H2AC12 H2AC12 NSD1 NSD1 RCOR1 RCOR1 HDAC2 HDAC2 KAT14 KAT14 G2E3 G2E3 KDM7A KDM7A PHF7 PHF7 CHD5 CHD5 ATF2 ATF2 KMT5B KMT5B G3SYD8_LOXAF G3SYD8_LOXAF KANSL3 KANSL3 NFKB2 NFKB2 SMARCB1 SMARCB1 H2AC6 H2AC6 LOC100669973 LOC100669973 MACROH2A1 MACROH2A1 CCND1 CCND1 SMYD1 SMYD1 KMT2C KMT2C KDM1A KDM1A NSD2 NSD2 EHMT2 EHMT2 ING4 ING4 JADE3 JADE3 AIRE AIRE ARID4A ARID4A OGT OGT NCOA2 NCOA2 ARID5A ARID5A NFKB1 NFKB1 SMYD5 SMYD5 GATAD2A GATAD2A G3T476_LOXAF G3T476_LOXAF SMARCC1 SMARCC1 TADA1 TADA1 MORF4L1 MORF4L1 KDM5A KDM5A G3T4Q6_LOXAF G3T4Q6_LOXAF KMT2D KMT2D MSL1 MSL1 WDR73 WDR73 PRMT9 PRMT9 PADI3 PADI3 HAT1 HAT1 G3T5C6_LOXAF G3T5C6_LOXAF PHF20 PHF20 YEATS2 YEATS2 EZH1 EZH1 ELP6 ELP6 PADI6 PADI6 CDK4 CDK4 HR HR RCOR3 RCOR3 LOC100675119 LOC100675119 SUPT7L SUPT7L WDR5 WDR5 ZZZ3 ZZZ3 ELP4 ELP4 MECOM MECOM EHMT1 EHMT1 CCDC153 CCDC153 ARID1B ARID1B SETDB2 SETDB2 KMT5A KMT5A BRMS1 BRMS1 MBIP MBIP VPS72 VPS72 ACTL6A ACTL6A RBBP7 RBBP7 KAT8 KAT8 SMARCA2 SMARCA2 KANSL1L KANSL1L SMYD2 SMYD2 PHF11 PHF11 KANSL2 KANSL2 NCOA1 NCOA1 ATF7IP2 ATF7IP2 KDM6A KDM6A SMARCC2 SMARCC2 ZC3H12B ZC3H12B SMYD4 SMYD4 SMARCE1 SMARCE1 ARID5B ARID5B RIOX2 RIOX2 PBRM1 PBRM1 WDR5B WDR5B PHF8 PHF8 BRPF1 BRPF1 ATF7IP ATF7IP DR1 DR1 ARID1A ARID1A BRMS1L BRMS1L PRMT1 PRMT1 HMG20A HMG20A MRGBP MRGBP SETD3 SETD3 PRMT3 PRMT3 ZC3H12A ZC3H12A MEAF6 MEAF6 KMT2B KMT2B AEBP2 AEBP2 GPS2 GPS2 DPY30 DPY30 BRPF3 BRPF3 ENSLAFP00000016306 ENSLAFP00000016306 ELP2 ELP2 SUV39H2 SUV39H2 ZC3H12D ZC3H12D MSL3 MSL3 SETD1A SETD1A LOC100657920 LOC100657920 SAP130 SAP130 CHD4 CHD4 PRMT6 PRMT6 H2AC14 H2AC14 HMG20B HMG20B G3TRX7_LOXAF G3TRX7_LOXAF G3TS46_LOXAF G3TS46_LOXAF ENSLAFP00000018530 ENSLAFP00000018530 KDM4B KDM4B LOC100675676 LOC100675676 KDM4D KDM4D SETD1B SETD1B LOC111752374 LOC111752374 JMJD6 JMJD6 HCFC1 HCFC1 COPRS COPRS G3TUA0_LOXAF G3TUA0_LOXAF ENSLAFP00000019204 ENSLAFP00000019204 H4C11 H4C11 KDM3A KDM3A PADI4 PADI4 ING3 ING3 KANSL1 KANSL1 MACROH2A2 MACROH2A2 PHF21B PHF21B MSL2 MSL2 H2BC11 H2BC11 KAT6A KAT6A SUPT20H SUPT20H ENSLAFP00000020650 ENSLAFP00000020650 PRMT2 PRMT2 SGF29 SGF29 LOC100659990 LOC100659990 MORF4L2 MORF4L2 RCOR2 RCOR2 ENSLAFP00000021075 ENSLAFP00000021075 EED EED LOC100674832 LOC100674832 TAF5L TAF5L LOC100660148 LOC100660148 RUVBL2 RUVBL2 LOC100658203 LOC100658203 H2BC5 H2BC5 G3U0S4_LOXAF G3U0S4_LOXAF KDM4C KDM4C H2AJ H2AJ G3U1Z3_LOXAF G3U1Z3_LOXAF ENSLAFP00000021886 ENSLAFP00000021886 G3U2N2_LOXAF G3U2N2_LOXAF ARID4B ARID4B TADA2A TADA2A LOC100673728 LOC100673728 ENSLAFP00000022509 ENSLAFP00000022509 LOC100659586 LOC100659586 LENG9 LENG9 G3U473_LOXAF G3U473_LOXAF ENSLAFP00000022709 ENSLAFP00000022709 ENSLAFP00000022732 ENSLAFP00000022732 ENSLAFP00000022963 ENSLAFP00000022963 H2BC12 H2BC12 TAF6L TAF6L KDM2B KDM2B DNMT3A DNMT3A ENSLAFP00000023570 ENSLAFP00000023570 KDM5C KDM5C G3U7W4_LOXAF G3U7W4_LOXAF LOC100665018 LOC100665018 ZC3H12C ZC3H12C PHF2 PHF2 G3U8T3_LOXAF G3U8T3_LOXAF ELP3 ELP3 ENSLAFP00000024415 ENSLAFP00000024415 REST REST G3U9G3_LOXAF G3U9G3_LOXAF G3U9H7_LOXAF G3U9H7_LOXAF G3U9J5_LOXAF G3U9J5_LOXAF G3U9V5_LOXAF G3U9V5_LOXAF G3UAG7_LOXAF G3UAG7_LOXAF G3UAU8_LOXAF G3UAU8_LOXAF H2BC3 H2BC3 BRD8 BRD8 PAX7 PAX7 H2BC18 H2BC18 KAT6B KAT6B PADI2 PADI2 WDR26 WDR26 PHF6 PHF6 ATXN7L3 ATXN7L3 CREB5 CREB5 H2AC1 H2AC1 ENSLAFP00000026171 ENSLAFP00000026171 G3UF27_LOXAF G3UF27_LOXAF RIOX1 RIOX1 G3UFS4_LOXAF G3UFS4_LOXAF RELA RELA KDM2A KDM2A G3UGT6_LOXAF G3UGT6_LOXAF ACTL6B ACTL6B PADI1 PADI1 NSD3 NSD3 MTA2 MTA2 KDM5B KDM5B LOC100656778 LOC100656778 SMARCD3 SMARCD3 RBBP5 RBBP5 SETD7 SETD7 ENSLAFP00000027918 ENSLAFP00000027918 ENSLAFP00000027938 ENSLAFP00000027938 ENSLAFP00000027955 ENSLAFP00000027955 ENSLAFP00000028008 ENSLAFP00000028008 SAP18 SAP18 ENSLAFP00000028190 ENSLAFP00000028190 KMT2A KMT2A DOT1L DOT1L PAX3 PAX3 G3UKU6_LOXAF G3UKU6_LOXAF BRWD1 BRWD1 NCOR1 NCOR1 H2BC21 H2BC21 ENSLAFP00000028568 ENSLAFP00000028568 LOC100671226 LOC100671226 SMARCD2 SMARCD2 MTA1 MTA1 LOC100661536 LOC100661536 SUZ12 SUZ12 KDM4A KDM4A G3UNK7_LOXAF G3UNK7_LOXAF ING5 ING5
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SETD6N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. (476 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (468 aa)
BRD1Bromodomain containing 1. (1188 aa)
CHD3Chromodomain helicase DNA binding protein 3. (1876 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa)
ELP1Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1334 aa)
ELP5Elongator acetyltransferase complex subunit 5. (301 aa)
JADE1Jade family PHD finger 1. (839 aa)
JADE2Jade family PHD finger 2. (844 aa)
PRDM16PR/SET domain 16. (1270 aa)
SUDS3SDS3 homolog, SIN3A corepressor complex component. (329 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1617 aa)
H2AC21Histone H2A; Belongs to the histone H2A family. (130 aa)
KDM3BLysine demethylase 3B. (1764 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (628 aa)
ASH1LASH1 like histone lysine methyltransferase. (1974 aa)
SAP30LSAP30 like. (182 aa)
RBBP4RB binding protein 4, chromatin remodeling factor. (425 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
GATAD2BGATA zinc finger domain containing 2B. (593 aa)
BRWD3Bromodomain and WD repeat domain containing 3. (1798 aa)
SAP30Sin3A associated protein 30. (115 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (613 aa)
PRMT7Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (696 aa)
MCRS1Microspherule protein 1. (463 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (99 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (1941 aa)
PHF21APHD finger protein 21A. (630 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
HCFC2Host cell factor C2. (728 aa)
TEX30Testis expressed 30. (225 aa)
LOC100661012Histone H2B; Belongs to the histone H2B family. (126 aa)
SETDB1SET domain bifurcated histone lysine methyltransferase 1. (1307 aa)
KMT2ELysine methyltransferase 2E. (1835 aa)
ARID2AT-rich interaction domain 2. (1749 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (576 aa)
HIST1H2BAHistone cluster 1 H2B family member a; Belongs to the histone H2B family. (127 aa)
KDM1BLysine demethylase 1B. (826 aa)
TMEM62Transmembrane protein 62. (608 aa)
RPS2S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
WDR77WD repeat domain 77. (348 aa)
MTA3Metastasis associated 1 family member 3. (532 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
SUPT3HSPT3 homolog, SAGA and STAGA complex component. (326 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (364 aa)
LOC111752376Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC100662145Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC12Histone H2A; Belongs to the histone H2A family. (128 aa)
NSD1Nuclear receptor binding SET domain protein 1. (2348 aa)
RCOR1REST corepressor 1. (369 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (487 aa)
KAT14Lysine acetyltransferase 14. (771 aa)
G2E3G2/M-phase specific E3 ubiquitin protein ligase. (718 aa)
KDM7ALysine demethylase 7A. (882 aa)
PHF7PHD finger protein 7. (382 aa)
CHD5Chromodomain helicase DNA binding protein 5. (1928 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (487 aa)
KMT5BLysine methyltransferase 5B. (883 aa)
G3SYD8_LOXAFHistone H2A; Belongs to the histone H2A family. (130 aa)
KANSL3KAT8 regulatory NSL complex subunit 3. (904 aa)
NFKB2Nuclear factor kappa B subunit 2. (896 aa)
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1. (360 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC100669973Histone H2B; Belongs to the histone H2B family. (126 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
SMYD1SET and MYND domain containing 1. (445 aa)
KMT2CUncharacterized protein. (2177 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (875 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1361 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1225 aa)
ING4Inhibitor of growth protein. (249 aa)
JADE3Jade family PHD finger 3. (824 aa)
AIREAutoimmune regulator. (557 aa)
ARID4AAT-rich interaction domain 4A. (1268 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
NCOA2Nuclear receptor coactivator. (1461 aa)
ARID5AAT-rich interaction domain 5A. (596 aa)
NFKB1Nuclear factor kappa B subunit 1. (973 aa)
SMYD5SMYD family member 5. (417 aa)
GATAD2AGATA zinc finger domain containing 2A. (628 aa)
G3T476_LOXAFUncharacterized protein. (131 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1099 aa)
TADA1Transcriptional adaptor 1. (335 aa)
MORF4L1Mortality factor 4 like 1. (362 aa)
KDM5ALysine demethylase 5A. (1582 aa)
G3T4Q6_LOXAFJmjC domain-containing protein. (236 aa)
KMT2DLysine methyltransferase 2D. (4936 aa)
MSL1MSL complex subunit 1. (614 aa)
WDR73WD repeat domain 73. (369 aa)
PRMT9Protein arginine methyltransferase 9; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (846 aa)
PADI3Peptidyl arginine deiminase 3. (664 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (422 aa)
G3T5C6_LOXAFUncharacterized protein. (127 aa)
PHF20PHD finger protein 20. (1025 aa)
YEATS2YEATS domain containing 2. (1402 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (747 aa)
ELP6Elongator acetyltransferase complex subunit 6. (266 aa)
PADI6Peptidyl arginine deiminase 6. (686 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (226 aa)
HRHR lysine demethylase and nuclear receptor corepressor. (1182 aa)
RCOR3REST corepressor 3. (478 aa)
LOC100675119Histone H2B; Belongs to the histone H2B family. (127 aa)
SUPT7LSPT7 like, STAGA complex gamma subunit. (412 aa)
WDR5WD repeat domain 5. (350 aa)
ZZZ3Uncharacterized protein. (909 aa)
ELP4Elongator acetyltransferase complex subunit 4. (360 aa)
MECOMMDS1 and EVI1 complex locus. (1042 aa)
EHMT1Euchromatic histone lysine methyltransferase 1. (846 aa)
CCDC153Coiled-coil domain containing 153. (201 aa)
ARID1BAT-rich interaction domain 1B. (1721 aa)
SETDB2SET domain bifurcated histone lysine methyltransferase 2. (711 aa)
KMT5ALysine methyltransferase 5A. (317 aa)
BRMS1BRMS1 transcriptional repressor and anoikis regulator. (248 aa)
MBIPMAP3K12 binding inhibitory protein 1. (345 aa)
VPS72Vacuolar protein sorting 72 homolog. (363 aa)
ACTL6AActin like 6A; Belongs to the actin family. (429 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (426 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (466 aa)
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1581 aa)
KANSL1LKAT8 regulatory NSL complex subunit 1 like. (991 aa)
SMYD2SET and MYND domain containing 2. (430 aa)
PHF11PHD finger protein 11. (298 aa)
KANSL2KAT8 regulatory NSL complex subunit 2. (488 aa)
NCOA1Nuclear receptor coactivator. (1444 aa)
ATF7IP2Activating transcription factor 7 interacting protein 2. (691 aa)
KDM6ALysine demethylase 6A. (1423 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1179 aa)
ZC3H12BZinc finger CCCH-type containing 12B. (837 aa)
SMYD4SET and MYND domain containing 4. (717 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa)
ARID5BAT-rich interaction domain 5B. (1188 aa)
RIOX2Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (463 aa)
PBRM1Polybromo 1. (1704 aa)
WDR5BWD repeat domain 5B. (330 aa)
PHF8PHD finger protein 8. (913 aa)
BRPF1Bromodomain and PHD finger containing 1. (1248 aa)
ATF7IPActivating transcription factor 7 interacting protein. (1259 aa)
DR1Down-regulator of transcription 1. (176 aa)
ARID1AAT-rich interaction domain 1A. (2180 aa)
BRMS1LBRMS1 like transcriptional repressor. (323 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
HMG20AHigh mobility group 20A. (347 aa)
MRGBPMRG domain binding protein. (204 aa)
SETD3Protein-histidine N-methyltransferase. (598 aa)
PRMT3Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (449 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (599 aa)
MEAF6MYST/Esa1 associated factor 6. (169 aa)
KMT2BLysine methyltransferase 2B. (2303 aa)
AEBP2AE binding protein 2. (494 aa)
GPS2G protein pathway suppressor 2. (327 aa)
DPY30Dpy-30 histone methyltransferase complex regulatory subunit. (99 aa)
BRPF3Bromodomain and PHD finger containing 3. (1201 aa)
ENSLAFP00000016306annotation not available (103 aa)
ELP2Elongator acetyltransferase complex subunit 2. (825 aa)
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (403 aa)
ZC3H12DC3H1-type domain-containing protein. (320 aa)
MSL3MSL complex subunit 3. (334 aa)
SETD1ASET domain containing 1A, histone lysine methyltransferase. (1691 aa)
LOC100657920Histone H2B; Belongs to the histone H2B family. (126 aa)
SAP130Sin3A associated protein 130. (1058 aa)
CHD4Uncharacterized protein. (1895 aa)
PRMT6Protein arginine methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (375 aa)
H2AC14Histone H2A; Belongs to the histone H2A family. (130 aa)
HMG20BHigh mobility group 20B. (316 aa)
G3TRX7_LOXAFHistone H2A; Belongs to the histone H2A family. (115 aa)
G3TS46_LOXAFUncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (124 aa)
ENSLAFP00000018530annotation not available (103 aa)
KDM4BLysine demethylase 4B. (1123 aa)
LOC100675676Histone domain-containing protein; Belongs to the histone H2B family. (127 aa)
KDM4DLysine demethylase 4D. (507 aa)
SETD1BSET domain containing 1B, histone lysine methyltransferase. (1772 aa)
LOC111752374Histone H2A; Belongs to the histone H2A family. (130 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (367 aa)
HCFC1Host cell factor C1. (2106 aa)
COPRSCoordinator of PRMT5 and differentiation stimulator. (176 aa)
G3TUA0_LOXAFUncharacterized protein. (262 aa)
ENSLAFP00000019204annotation not available (127 aa)
H4C11H4 clustered histone 11. (103 aa)
KDM3AUncharacterized protein. (372 aa)
PADI4Peptidyl arginine deiminase 4. (670 aa)
ING3Inhibitor of growth protein. (418 aa)
KANSL1KAT8 regulatory NSL complex subunit 1. (1103 aa)
MACROH2A2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
PHF21BPHD finger protein 21B. (436 aa)
MSL2MSL complex subunit 2. (602 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (135 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2016 aa)
SUPT20HUncharacterized protein. (535 aa)
ENSLAFP00000020650annotation not available (130 aa)
PRMT2Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (432 aa)
SGF29SAGA complex associated factor 29. (293 aa)
LOC100659990Histone H2A; Belongs to the histone H2A family. (130 aa)
MORF4L2Mortality factor 4 like 2. (288 aa)
RCOR2REST corepressor 2. (524 aa)
ENSLAFP00000021075annotation not available (130 aa)
EEDEmbryonic ectoderm development. (510 aa)
LOC100674832Histone H2A; Belongs to the histone H2A family. (131 aa)
TAF5LTATA-box binding protein associated factor 5 like. (589 aa)
LOC100660148Histone H2B; Belongs to the histone H2B family. (126 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (461 aa)
LOC100658203Histone H2A; Belongs to the histone H2A family. (130 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
G3U0S4_LOXAFUncharacterized protein. (1523 aa)
KDM4CLysine demethylase 4C. (1054 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
G3U1Z3_LOXAFHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (104 aa)
ENSLAFP00000021886annotation not available (130 aa)
G3U2N2_LOXAFS5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (231 aa)
ARID4BAT-rich interaction domain 4B. (1312 aa)
TADA2ATranscriptional adapter. (441 aa)
LOC100673728Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSLAFP00000022509annotation not available (126 aa)
LOC100659586Histone H2A; Belongs to the histone H2A family. (112 aa)
LENG9Uncharacterized protein. (451 aa)
G3U473_LOXAFUncharacterized protein. (225 aa)
ENSLAFP00000022709annotation not available (126 aa)
ENSLAFP00000022732annotation not available (103 aa)
ENSLAFP00000022963annotation not available (103 aa)
H2BC12Histone H2B; Belongs to the histone H2B family. (135 aa)
TAF6LTATA-box binding protein associated factor 6 like. (621 aa)
KDM2BLysine demethylase 2B. (1305 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa)
ENSLAFP00000023570annotation not available (130 aa)
KDM5CLysine demethylase 5C. (1502 aa)
G3U7W4_LOXAFRibosomal_S5_C domain-containing protein. (217 aa)
LOC100665018Histone domain-containing protein; Belongs to the histone H2B family. (122 aa)
ZC3H12CZinc finger CCCH-type containing 12C. (627 aa)
PHF2PHD finger protein 2. (1073 aa)
G3U8T3_LOXAFHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (104 aa)
ELP3Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (544 aa)
ENSLAFP00000024415annotation not available (130 aa)
RESTRE1 silencing transcription factor. (1067 aa)
G3U9G3_LOXAFHistone H2A; Belongs to the histone H2A family. (130 aa)
G3U9H7_LOXAFS5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (218 aa)
G3U9J5_LOXAFUncharacterized protein. (528 aa)
G3U9V5_LOXAFHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (105 aa)
G3UAG7_LOXAFS5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
G3UAU8_LOXAFUncharacterized protein. (528 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
BRD8Bromodomain containing 8. (953 aa)
PAX7Paired box 7. (505 aa)
H2BC18Histone H2B; Belongs to the histone H2B family. (126 aa)
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1699 aa)
PADI2Peptidyl arginine deiminase 2. (674 aa)
WDR26WD repeat domain 26. (640 aa)
PHF6PHD finger protein 6. (450 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (352 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
H2AC1Histone H2A; Belongs to the histone H2A family. (131 aa)
ENSLAFP00000026171annotation not available (130 aa)
G3UF27_LOXAFSET domain-containing protein. (338 aa)
RIOX1Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (610 aa)
G3UFS4_LOXAFUncharacterized protein. (259 aa)
RELARELA proto-oncogene, NF-kB subunit. (555 aa)
KDM2ALysine demethylase 2A. (1161 aa)
G3UGT6_LOXAFHistone H2A; Belongs to the histone H2A family. (136 aa)
ACTL6BActin like 6B; Belongs to the actin family. (373 aa)
PADI1Peptidyl arginine deiminase 1. (661 aa)
NSD3Nuclear receptor binding SET domain protein 3. (1443 aa)
MTA2Metastasis associated 1 family member 2. (667 aa)
KDM5BLysine demethylase 5B. (1476 aa)
LOC100656778Histone H2A; Belongs to the histone H2A family. (129 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (485 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (541 aa)
SETD7Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes. (366 aa)
ENSLAFP00000027918annotation not available (126 aa)
ENSLAFP00000027938annotation not available (103 aa)
ENSLAFP00000027955annotation not available (103 aa)
ENSLAFP00000028008annotation not available (126 aa)
SAP18Histone deacetylase complex subunit SAP18; Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or durin [...] (153 aa)
ENSLAFP00000028190annotation not available (104 aa)
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3964 aa)
DOT1LHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1546 aa)
PAX3Paired box 3. (492 aa)
G3UKU6_LOXAFHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (104 aa)
BRWD1Bromodomain and WD repeat domain containing 1. (2328 aa)
NCOR1Nuclear receptor corepressor 1. (2457 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSLAFP00000028568annotation not available (130 aa)
LOC100671226Histone H2A; Belongs to the histone H2A family. (130 aa)
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (531 aa)
MTA1Metastasis associated 1. (660 aa)
LOC100661536Uncharacterized protein. (307 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)
KDM4AUncharacterized protein. (1067 aa)
G3UNK7_LOXAFHistone H2B; Belongs to the histone H2B family. (134 aa)
ING5Inhibitor of growth family member 5. (228 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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