STRINGSTRING
LOC100667589 LOC100667589 G3TWH0_LOXAF G3TWH0_LOXAF CENPU CENPU CENPF CENPF CENPA CENPA G3TYP9_LOXAF G3TYP9_LOXAF G3TZ65_LOXAF G3TZ65_LOXAF G3U0R3_LOXAF G3U0R3_LOXAF ANAPC11 ANAPC11 G3U1J3_LOXAF G3U1J3_LOXAF SPC24 SPC24 PLK1 PLK1 SKA1 SKA1 CLIP2 CLIP2 SPC25 SPC25 ANAPC2 ANAPC2 NDC80 NDC80 CENPN CENPN KIF2C KIF2C CENPQ CENPQ SKA2 SKA2 CDC16 CDC16 UBE2C UBE2C NUP85 NUP85 NUP37 NUP37 UBE2D1 UBE2D1 RANBP2 RANBP2 NUF2 NUF2 G3SL82_LOXAF G3SL82_LOXAF KNL1 KNL1 G3U3Z9_LOXAF G3U3Z9_LOXAF G3U524_LOXAF G3U524_LOXAF NUDC NUDC G3U6P2_LOXAF G3U6P2_LOXAF MAPRE3 MAPRE3 PPP2CB PPP2CB KIF2B KIF2B G3U933_LOXAF G3U933_LOXAF RCC2 RCC2 SGO2 SGO2 PMF1 PMF1 G3UFD7_LOXAF G3UFD7_LOXAF MIS12 MIS12 G3UHK4_LOXAF G3UHK4_LOXAF RANGAP1 RANGAP1 ZW10 ZW10 G3ULR5_LOXAF G3ULR5_LOXAF SPDL1 SPDL1 PPP2R5D PPP2R5D B9D2 B9D2 MEIOC MEIOC ANAPC1 ANAPC1 CDCA8 CDCA8 PPP2R1A PPP2R1A UBE2S UBE2S AURKB AURKB PPP2R1B PPP2R1B XPO1 XPO1 PPP2R5C PPP2R5C AURKC AURKC CKAP5 CKAP5 SGO1 SGO1 CENPL CENPL G3TPM1_LOXAF G3TPM1_LOXAF ANAPC16 ANAPC16 FAM89A FAM89A LOC100668722 LOC100668722 CDC20 CDC20 DYNC1I2 DYNC1I2 DYNC1I1 DYNC1I1 CENPE CENPE PPP2CA PPP2CA KNTC1 KNTC1 CLIP1 CLIP1 MTUS2 MTUS2 NUP107 NUP107 CENPM CENPM MAPRE1 MAPRE1 MAPRE2 MAPRE2 NUP160 NUP160 ERCC6L ERCC6L NDE1 NDE1 SEC13 SEC13 CENPO CENPO DYNC1H1 DYNC1H1 DYNLL2 DYNLL2 ZWINT ZWINT ERCC6L2 ERCC6L2 NUP98 NUP98 BUB3 BUB3 DYNC1LI1 DYNC1LI1 NUP43 NUP43 ANAPC4 ANAPC4 NSL1 NSL1 PPP2R5E PPP2R5E BUB1B BUB1B CDC27 CDC27 KIF18A KIF18A CENPC CENPC CENPI CENPI FAM89B FAM89B PPP2R5A PPP2R5A KIF2A KIF2A AHCTF1 AHCTF1 ANAPC10 ANAPC10 DYNC1LI2 DYNC1LI2 MAD1L1 MAD1L1 BUB1 BUB1 CDC26 CDC26 CDC20B CDC20B PPP2R5B PPP2R5B CENPK CENPK ANAPC5 ANAPC5 G3SYJ3_LOXAF G3SYJ3_LOXAF BIRC5 BIRC5 CENPT CENPT PAFAH1B1 PAFAH1B1 SEH1L SEH1L DSN1 DSN1 NUP133 NUP133 ANAPC7 ANAPC7 NDEL1 NDEL1 CLASP1 CLASP1 CDC23 CDC23
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100667589HORMA domain-containing protein. (205 aa)
G3TWH0_LOXAFSerine/threonine-protein phosphatase. (285 aa)
CENPUUncharacterized protein. (402 aa)
CENPFCentromere protein F. (2833 aa)
CENPACentromere protein A. (144 aa)
G3TYP9_LOXAFHORMA domain-containing protein. (89 aa)
G3TZ65_LOXAFINCENP_N domain-containing protein. (491 aa)
G3U0R3_LOXAFUBIQUITIN_CONJUGAT_2 domain-containing protein. (179 aa)
ANAPC11RING-type domain-containing protein. (84 aa)
G3U1J3_LOXAFINCENP_ARK-bind domain-containing protein. (267 aa)
SPC24Uncharacterized protein. (60 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (255 aa)
CLIP2CAP-Gly domain containing linker protein 2. (1046 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (226 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (834 aa)
NDC80NDC80 kinetochore complex component. (645 aa)
CENPNCentromere protein N. (342 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (670 aa)
CENPQCentromere protein Q. (269 aa)
SKA2Spindle and kinetochore associated complex subunit 2. (109 aa)
CDC16Cell division cycle 16. (624 aa)
UBE2CUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (658 aa)
NUP37Nucleoporin 37. (326 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
RANBP2RAN binding protein 2. (3072 aa)
NUF2NUF2 component of NDC80 kinetochore complex. (464 aa)
G3SL82_LOXAFUncharacterized protein. (1403 aa)
KNL1Uncharacterized protein. (424 aa)
G3U3Z9_LOXAFUncharacterized protein. (134 aa)
G3U524_LOXAFHORMA domain-containing protein. (89 aa)
NUDCNuclear distribution C, dynein complex regulator. (333 aa)
G3U6P2_LOXAFMetallophos domain-containing protein. (98 aa)
MAPRE3Microtubule associated protein RP/EB family member 3. (284 aa)
PPP2CBSerine/threonine-protein phosphatase. (276 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (670 aa)
G3U933_LOXAFUBIQUITIN_CONJUGAT_2 domain-containing protein. (172 aa)
RCC2Regulator of chromosome condensation 2. (522 aa)
SGO2Shugoshin 2. (1191 aa)
PMF1Uncharacterized protein. (152 aa)
G3UFD7_LOXAFUncharacterized protein. (335 aa)
MIS12MIS12 kinetochore complex component. (206 aa)
G3UHK4_LOXAFHORMA domain-containing protein. (105 aa)
RANGAP1Ran GTPase activating protein 1. (602 aa)
ZW10Zw10 kinetochore protein. (781 aa)
G3ULR5_LOXAFHORMA domain-containing protein. (82 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (555 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (597 aa)
B9D2B9 domain containing 2. (175 aa)
MEIOCMeiosis specific with coiled-coil domain. (934 aa)
ANAPC1Anaphase promoting complex subunit 1. (1944 aa)
CDCA8Cell division cycle associated 8. (279 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (223 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (345 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (697 aa)
XPO1Exportin 1. (1073 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (493 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (284 aa)
CKAP5Cytoskeleton associated protein 5. (2033 aa)
SGO1Shugoshin 1. (529 aa)
CENPLCentromere protein L. (346 aa)
G3TPM1_LOXAFKnl1_RWD_C domain-containing protein. (332 aa)
ANAPC16Anaphase promoting complex subunit 16. (108 aa)
FAM89AFamily with sequence similarity 89 member A. (176 aa)
LOC100668722HORMA domain-containing protein. (205 aa)
CDC20Cell division cycle 20. (499 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (638 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (645 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2694 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
KNTC1Kinetochore associated 1. (2214 aa)
CLIP1CAP-Gly domain containing linker protein 1. (1438 aa)
MTUS2Uncharacterized protein. (275 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (928 aa)
CENPMCentromere protein M. (180 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
MAPRE2Microtubule associated protein RP/EB family member 2. (326 aa)
NUP160Nucleoporin 160. (1402 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1229 aa)
NDE1NudE neurodevelopment protein 1. (347 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (321 aa)
CENPOCentromere protein O. (282 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4561 aa)
DYNLL2Dynein light chain. (89 aa)
ZWINTZW10 interacting kinetochore protein. (231 aa)
ERCC6L2ERCC excision repair 6 like 2. (703 aa)
NUP98Nucleoporin 98. (1224 aa)
BUB3BUB3 mitotic checkpoint protein. (325 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (452 aa)
NUP43Nucleoporin 43. (380 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (283 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
BUB1BUncharacterized protein. (1061 aa)
CDC27Cell division cycle 27. (831 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (898 aa)
CENPCCentromere protein C. (933 aa)
CENPICentromere protein I. (735 aa)
FAM89BFamily with sequence similarity 89 member B. (192 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (426 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (717 aa)
AHCTF1AT-hook containing transcription factor 1. (2286 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (718 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1061 aa)
CDC26Cell division cycle 26. (85 aa)
CDC20BCell division cycle 20B. (486 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (435 aa)
CENPKCentromere protein K. (270 aa)
ANAPC5Anaphase promoting complex subunit 5. (743 aa)
G3SYJ3_LOXAFDynein light chain. (85 aa)
BIRC5Baculoviral IAP repeat containing 5. (140 aa)
CENPTCentromere protein T. (539 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (411 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (360 aa)
DSN1DSN1 component of MIS12 kinetochore complex. (347 aa)
NUP133Nucleoporin 133. (1156 aa)
ANAPC7Anaphase promoting complex subunit 7. (564 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (345 aa)
CLASP1Cytoplasmic linker associated protein 1. (1539 aa)
CDC23Cell division cycle 23. (597 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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