STRINGSTRING
CHD3 CHD3 TAF1B TAF1B GTF2H5 GTF2H5 TTF1 TTF1 CD3EAP CD3EAP RRN3 RRN3 RBBP4 RBBP4 GATAD2B GATAD2B POLR2H POLR2H MNAT1 MNAT1 DMTF1 DMTF1 MTA3 MTA3 HDAC1 HDAC1 POLR2K POLR2K HDAC2 HDAC2 TBP TBP TAF1C TAF1C CHD5 CHD5 ERCC2 ERCC2 POLR1B POLR1B EHMT2 EHMT2 AIRE AIRE TWISTNB TWISTNB GATAD2A GATAD2A GTF2H2 GTF2H2 GTF2H1 GTF2H1 CDK7 CDK7 ZNRD1 ZNRD1 POLR2F POLR2F RBBP7 RBBP7 UBN2 UBN2 ERCC6 ERCC6 ERCC3 ERCC3 POLR1A POLR1A TAF1A TAF1A TBPL2 TBPL2 GTF2H4 GTF2H4 TAF1D TAF1D CHD4 CHD4 GTF2H3 GTF2H3 POLR1E POLR1E POLR2E POLR2E MTA2 MTA2 UBTF UBTF CCNH CCNH G3UJQ0_LOXAF G3UJQ0_LOXAF POLR1C POLR1C MTA1 MTA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHD3Chromodomain helicase DNA binding protein 3. (1876 aa)
TAF1BTATA-box binding protein associated factor, RNA polymerase I subunit B. (523 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
TTF1Transcription termination factor 1. (731 aa)
CD3EAPCD3e molecule associated protein. (417 aa)
RRN3RRN3 homolog, RNA polymerase I transcription factor. (658 aa)
RBBP4RB binding protein 4, chromatin remodeling factor. (425 aa)
GATAD2BGATA zinc finger domain containing 2B. (593 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (308 aa)
DMTF1Cyclin D binding myb like transcription factor 1. (760 aa)
MTA3Metastasis associated 1 family member 3. (532 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
POLR2KUncharacterized protein. (57 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (487 aa)
TBPTATA-box binding protein. (314 aa)
TAF1CTATA-box binding protein associated factor, RNA polymerase I subunit C. (843 aa)
CHD5Chromodomain helicase DNA binding protein 5. (1928 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1137 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1225 aa)
AIREAutoimmune regulator. (557 aa)
TWISTNBTWIST neighbor. (332 aa)
GATAD2AGATA zinc finger domain containing 2A. (628 aa)
GTF2H2General transcription factor IIH subunit. (393 aa)
GTF2H1General transcription factor IIH subunit 1. (554 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
ZNRD1DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (426 aa)
UBN2Ubinuclein 2. (1275 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1432 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
POLR1ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1716 aa)
TAF1ATATA-box binding protein associated factor, RNA polymerase I subunit A. (455 aa)
TBPL2TATA-box binding protein like 2. (351 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
TAF1DTATA-box binding protein associated factor, RNA polymerase I subunit D. (270 aa)
CHD4Uncharacterized protein. (1895 aa)
GTF2H3General transcription factor IIH subunit 3. (315 aa)
POLR1ERNA polymerase I subunit E. (471 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
MTA2Metastasis associated 1 family member 2. (667 aa)
UBTFUpstream binding transcription factor. (764 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
G3UJQ0_LOXAFUncharacterized protein. (383 aa)
POLR1CRNA polymerase I and III subunit C. (301 aa)
MTA1Metastasis associated 1. (660 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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