(46 nodes) RNA Polymerase III Transcription network (Loxodonta africana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	POLR2K	Uncharacterized protein. (57 aa)
	SSB	Uncharacterized protein. (422 aa)
	NFIB	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
	POLR3D	RNA polymerase III subunit D. (398 aa)
	POLR3B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1138 aa)
	GTF3C3	General transcription factor IIIC subunit 3. (883 aa)
	BRF1	BRF1 RNA polymerase III transcription initiation factor subunit. (588 aa)
	GTF3C5	General transcription factor IIIC subunit 5. (514 aa)
	POLR1C	RNA polymerase I and III subunit C. (301 aa)
	NFIX	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (515 aa)
	BRF2	BRF2 RNA polymerase III transcription initiation factor subunit. (418 aa)
	POLR3K	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa)
	POLR3C	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (533 aa)
	CRCP	CGRP receptor component. (144 aa)
	POLR2E	RNA polymerase II subunit E. (210 aa)
	G3U7V1_LOXAF	DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (220 aa)
	G3U6N7_LOXAF	SANT domain-containing protein. (468 aa)
	G3U2Z3_LOXAF	HTH La-type RNA-binding domain-containing protein. (294 aa)
	NFIA	Uncharacterized protein. (296 aa)
	ZNF143	Zinc finger protein 143. (637 aa)
	ZNF76	Zinc finger protein 76. (570 aa)
	NFIC	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (438 aa)
	G3TUK0_LOXAF	CTF/NF-I domain-containing protein. (200 aa)
	BDP1	Uncharacterized protein. (1088 aa)
	POLR2H	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	POLR3F	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa)
	GTF3C6	General transcription factor IIIC subunit 6. (225 aa)
	G3TTL3_LOXAF	Uncharacterized protein. (381 aa)
	GTF3A	General transcription factor IIIA. (370 aa)
	GTF3C1	General transcription factor IIIC subunit 1. (2112 aa)
	SNAPC2	Small nuclear RNA activating complex polypeptide 2. (337 aa)
	POU2F1	POU domain protein. (757 aa)
	G3TJ62_LOXAF	Uncharacterized protein. (463 aa)
	TBPL2	TATA-box binding protein like 2. (351 aa)
	POLR3E	RNA polymerase III subunit E. (712 aa)
	POLR3A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1391 aa)
	G3TGN1_LOXAF	DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (225 aa)
	GTF3C4	General transcription factor IIIC subunit 4. (821 aa)
	GTF3C2	General transcription factor IIIC subunit 2. (921 aa)
	TBPL1	TATA-box binding protein like 1. (186 aa)
	SNAPC3	Small nuclear RNA activating complex polypeptide 3. (418 aa)
	SNAPC1	Small nuclear RNA activating complex polypeptide 1. (372 aa)
	POLR2F	RNA polymerase II subunit F. (127 aa)
	SNAPC5	Small nuclear RNA activating complex polypeptide 5. (99 aa)
	TBP	TATA-box binding protein. (314 aa)
	POLR3H	RNA polymerase III subunit H. (204 aa)

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDP1	BRF1	ENSLAFP00000002638	ENSLAFP00000001803	Uncharacterized protein.	BRF1 RNA polymerase III transcription initiation factor subunit.	0.954
BDP1	BRF2	ENSLAFP00000002638	ENSLAFP00000026261	Uncharacterized protein.	BRF2 RNA polymerase III transcription initiation factor subunit.	0.908
BDP1	CRCP	ENSLAFP00000002638	ENSLAFP00000024675	Uncharacterized protein.	CGRP receptor component.	0.861
BDP1	G3TGN1_LOXAF	ENSLAFP00000002638	ENSLAFP00000013650	Uncharacterized protein.	DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.	0.704
BDP1	G3TJ62_LOXAF	ENSLAFP00000002638	ENSLAFP00000014748	Uncharacterized protein.	Uncharacterized protein.	0.527
BDP1	G3U6N7_LOXAF	ENSLAFP00000002638	ENSLAFP00000023495	Uncharacterized protein.	SANT domain-containing protein.	0.900
BDP1	G3U7V1_LOXAF	ENSLAFP00000002638	ENSLAFP00000023909	Uncharacterized protein.	DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.	0.704
BDP1	GTF3A	ENSLAFP00000002638	ENSLAFP00000018500	Uncharacterized protein.	General transcription factor IIIA.	0.623
BDP1	GTF3C1	ENSLAFP00000002638	ENSLAFP00000018389	Uncharacterized protein.	General transcription factor IIIC subunit 1.	0.734
BDP1	GTF3C2	ENSLAFP00000002638	ENSLAFP00000012036	Uncharacterized protein.	General transcription factor IIIC subunit 2.	0.506
BDP1	GTF3C3	ENSLAFP00000002638	ENSLAFP00000001498	Uncharacterized protein.	General transcription factor IIIC subunit 3.	0.891
BDP1	GTF3C4	ENSLAFP00000002638	ENSLAFP00000012898	Uncharacterized protein.	General transcription factor IIIC subunit 4.	0.474
BDP1	GTF3C5	ENSLAFP00000002638	ENSLAFP00000002546	Uncharacterized protein.	General transcription factor IIIC subunit 5.	0.766
BDP1	POLR1C	ENSLAFP00000002638	ENSLAFP00000028280	Uncharacterized protein.	RNA polymerase I and III subunit C.	0.817
BDP1	POLR2E	ENSLAFP00000002638	ENSLAFP00000024181	Uncharacterized protein.	RNA polymerase II subunit E.	0.756
BDP1	POLR2F	ENSLAFP00000002638	ENSLAFP00000010559	Uncharacterized protein.	RNA polymerase II subunit F.	0.776
BDP1	POLR2H	ENSLAFP00000002638	ENSLAFP00000002981	Uncharacterized protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.781
BDP1	POLR2K	ENSLAFP00000002638	ENSLAFP00000004399	Uncharacterized protein.	Uncharacterized protein.	0.775
BDP1	POLR3A	ENSLAFP00000002638	ENSLAFP00000014034	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.912
BDP1	POLR3B	ENSLAFP00000002638	ENSLAFP00000001362	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.873

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