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| PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (974 aa) | ||||
| ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3055 aa) | ||||
| RGS13 | Regulator of G protein signaling 13. (158 aa) | ||||
| CLOCK | Clock circadian regulator. (849 aa) | ||||
| RGS6 | Regulator of G protein signaling 6. (414 aa) | ||||
| DDB1 | Damage specific DNA binding protein 1. (1140 aa) | ||||
| HIF1A | Hypoxia inducible factor 1 subunit alpha. (836 aa) | ||||
| BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1854 aa) | ||||
| PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) | ||||
| CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (352 aa) | ||||
| MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (492 aa) | ||||
| APTX | Aprataxin. (344 aa) | ||||
| GRK7 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (553 aa) | ||||
| PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) | ||||
| GRK1 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (594 aa) | ||||
| RAD51C | RAD51 paralog C. (368 aa) | ||||
| RHO | Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity). (348 aa) | ||||
| GIT2 | GIT ArfGAP 2. (760 aa) | ||||
| FANCA | FA complementation group A. (1436 aa) | ||||
| BCHE | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (602 aa) | ||||
| ABCB1 | ATP binding cassette subfamily B member 1. (1240 aa) | ||||
| FBXO44 | Uncharacterized protein. (255 aa) | ||||
| NFE2L2 | Nuclear factor, erythroid 2 like 2. (607 aa) | ||||
| RAD52 | RAD52 homolog, DNA repair protein. (411 aa) | ||||
| NOX4 | NADPH oxidase 4. (579 aa) | ||||
| RXFP3 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (445 aa) | ||||
| RGSL1 | RGS domain-containing protein. (409 aa) | ||||
| ARRB1 | Arrestin beta 1. (418 aa) | ||||
| PARP2 | Poly [ADP-ribose] polymerase. (569 aa) | ||||
| PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa) | ||||
| CUL4B | Cullin 4B; Belongs to the cullin family. (946 aa) | ||||
| ADRB2 | Adrenoceptor beta 2. (415 aa) | ||||
| POMC | Corticotropin-like intermediary peptide; [Corticotropin]: Stimulates the adrenal glands to release cortisol. [Melanocyte-stimulating hormone beta]: Increases the pigmentation of skin by increasing melanin production in melanocytes. [Met-enkephalin]: Endogenous opiate; Belongs to the POMC family. (247 aa) | ||||
| CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa) | ||||
| CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa) | ||||
| LIG4 | DNA ligase. (913 aa) | ||||
| HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa) | ||||
| RGS2 | Regulator of G protein signaling 2. (212 aa) | ||||
| INSR | Tyrosine-protein kinase receptor. (1366 aa) | ||||