(15 nodes) Tumour necrosis factor family. network (Loxodonta africana)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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Known Interactions

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Your Input:
	CD40LG	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
	LTA	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family. (205 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
	CD70	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (198 aa)
	TNFSF11	Tumor necrosis factor ligand 6B; Belongs to the tumor necrosis factor family. (319 aa)
	TNFSF13B	TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (322 aa)
	FASLG	Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (277 aa)
	TNFSF15	TNF superfamily member 15. (254 aa)
	TNFSF10	Tumor necrosis factor ligand superfamily member. (287 aa)
	TNFSF8	Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family. (235 aa)
	TNFSF14	Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family. (241 aa)
	EDA	Ectodysplasin A; Belongs to the tumor necrosis factor family. (224 aa)
	TNFSF13	TNF superfamily member 13; Belongs to the tumor necrosis factor family. (243 aa)
	TNFSF9	TNF superfamily member 9; Belongs to the tumor necrosis factor family. (244 aa)
	TNFSF4	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (143 aa)

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD40LG	CD70	ENSLAFP00000004664	ENSLAFP00000007375	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.735
CD40LG	FASLG	ENSLAFP00000004664	ENSLAFP00000010924	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family.	0.572
CD40LG	LTA	ENSLAFP00000004664	ENSLAFP00000006571	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	0.592
CD40LG	TNFSF11	ENSLAFP00000004664	ENSLAFP00000009410	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Tumor necrosis factor ligand 6B; Belongs to the tumor necrosis factor family.	0.516
CD40LG	TNFSF13B	ENSLAFP00000004664	ENSLAFP00000010504	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNF superfamily member 13b; Belongs to the tumor necrosis factor family.	0.776
CD40LG	TNFSF14	ENSLAFP00000004664	ENSLAFP00000016825	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family.	0.469
CD40LG	TNFSF4	ENSLAFP00000004664	ENSLAFP00000004188	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.638
CD40LG	TNFSF9	ENSLAFP00000004664	ENSLAFP00000027923	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNF superfamily member 9; Belongs to the tumor necrosis factor family.	0.519
CD70	CD40LG	ENSLAFP00000007375	ENSLAFP00000004664	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.735
CD70	TNFSF4	ENSLAFP00000007375	ENSLAFP00000004188	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.484
CD70	TNFSF9	ENSLAFP00000007375	ENSLAFP00000027923	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	TNF superfamily member 9; Belongs to the tumor necrosis factor family.	0.597
FASLG	CD40LG	ENSLAFP00000010924	ENSLAFP00000004664	Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.572
LTA	CD40LG	ENSLAFP00000006571	ENSLAFP00000004664	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.592
LTA	TNF	ENSLAFP00000006571	ENSLAFP00000006573	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.910
LTA	TNFSF11	ENSLAFP00000006571	ENSLAFP00000009410	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	Tumor necrosis factor ligand 6B; Belongs to the tumor necrosis factor family.	0.549
LTA	TNFSF13B	ENSLAFP00000006571	ENSLAFP00000010504	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	TNF superfamily member 13b; Belongs to the tumor necrosis factor family.	0.432
LTA	TNFSF14	ENSLAFP00000006571	ENSLAFP00000016825	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family.	0.447
TNF	LTA	ENSLAFP00000006573	ENSLAFP00000006571	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	0.910
TNFSF11	CD40LG	ENSLAFP00000009410	ENSLAFP00000004664	Tumor necrosis factor ligand 6B; Belongs to the tumor necrosis factor family.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.516
TNFSF11	LTA	ENSLAFP00000009410	ENSLAFP00000006571	Tumor necrosis factor ligand 6B; Belongs to the tumor necrosis factor family.	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	0.549

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