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ACAA1 ACAA1 FABP4 FABP4 ACSL3 ACSL3 MMP1 MMP1 FABP7 FABP7 SLC27A6 SLC27A6 SLC27A4 SLC27A4 SLC27A5 SLC27A5 ACSBG1 ACSBG1 ADIPOQ ADIPOQ SCP2 SCP2 ACOX1 ACOX1 SLC27A2 SLC27A2 FADS2 FADS2 DBI DBI ME1 ME1 LPL LPL ANGPTL4 ANGPTL4 CYP7A1 CYP7A1 ACSBG2 ACSBG2 ME3 ME3 UCP1 UCP1 ACSL1 ACSL1 GK GK RXRG RXRG ACSL5 ACSL5 NR1H3 NR1H3 PCK1 PCK1 FABP9 FABP9 PLTP PLTP EHHADH EHHADH APOA5 APOA5 CD36 CD36 PLIN2 PLIN2 PPARA PPARA CPT2 CPT2 FABP1 FABP1 ACADL ACADL PCK2 PCK2 SCD5 SCD5 CYP27A1 CYP27A1 PPARD PPARD SCD SCD HMGCS1 HMGCS1 PLIN5 PLIN5 ACSL4 ACSL4 FABP3 FABP3 ILK ILK ACSL6 ACSL6 FABP2 FABP2 ACOX3 ACOX3 PDPK1 PDPK1 APOA2 APOA2 SLC27A1 SLC27A1 AQP7 AQP7 PPARG PPARG PLIN4 PLIN4 GK2 GK2 FABP5 FABP5 FABP6 FABP6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (426 aa)
FABP4Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
MMP1Matrix metallopeptidase 1. (465 aa)
FABP7Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
SLC27A6Solute carrier family 27 member 6. (618 aa)
SLC27A4Solute carrier family 27 member 4. (644 aa)
SLC27A5Solute carrier family 27 member 5. (539 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (683 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (245 aa)
SCP2Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (515 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
SLC27A2Solute carrier family 27 member 2. (620 aa)
FADS2Fatty acid desaturase 2. (447 aa)
DBIDiazepam binding inhibitor, acyl-CoA binding protein. (103 aa)
ME1Malic enzyme. (572 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (472 aa)
ANGPTL4Angiopoietin like 4. (411 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (503 aa)
ACSBG2Acyl-CoA synthetase bubblegum family member 2. (640 aa)
ME3Malic enzyme. (604 aa)
UCP1Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (698 aa)
GKUncharacterized protein; Belongs to the FGGY kinase family. (549 aa)
RXRGRetinoid X receptor gamma. (463 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (683 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (447 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (624 aa)
FABP9Fatty acid binding protein 9; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
PLTPPhospholipid transfer protein. (493 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
APOA5Apolipoprotein A5. (371 aa)
CD36CD36 molecule; Belongs to the CD36 family. (474 aa)
PLIN2Perilipin; Belongs to the perilipin family. (428 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
CPT2Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (610 aa)
FABP1Fatty acid binding protein 1. (127 aa)
ACADLAcyl-CoA dehydrogenase long chain. (430 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (663 aa)
SCD5Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (259 aa)
CYP27A1Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (447 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
SCDStearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (365 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa)
PLIN5Perilipin; Belongs to the perilipin family. (371 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (722 aa)
FABP3Fatty acid binding protein 3; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
ILKIntegrin linked kinase. (452 aa)
ACSL6AMP-binding domain-containing protein. (723 aa)
FABP2Fatty acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (699 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (558 aa)
APOA2Apolipoprotein A2. (105 aa)
SLC27A1Uncharacterized protein. (317 aa)
AQP7Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (239 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
PLIN4Perilipin 4. (1415 aa)
GK2Glycerol kinase 2; Belongs to the FGGY kinase family. (553 aa)
FABP5Fatty acid binding protein 5. (134 aa)
FABP6Fatty acid binding protein 6. (127 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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