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CTSZ | Cathepsin Z; Belongs to the peptidase C1 family. (305 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (229 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1371 aa) | ||||
LOC100667382 | Uncharacterized protein; Belongs to the peptidase C1 family. (335 aa) | ||||
PIK3R2 | Uncharacterized protein. (724 aa) | ||||
CTSC | Cathepsin C; Belongs to the peptidase C1 family. (463 aa) | ||||
ACTB | Actin beta. (381 aa) | ||||
NTRK1 | Tyrosine-protein kinase receptor. (795 aa) | ||||
BAK1 | BCL2 antagonist/killer 1. (211 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1038 aa) | ||||
CTSW | Cathepsin W; Belongs to the peptidase C1 family. (376 aa) | ||||
BCL2L1 | BCL2 like 1. (234 aa) | ||||
PARP4 | Poly [ADP-ribose] polymerase. (1241 aa) | ||||
LMNA | Lamin A/C; Belongs to the intermediate filament family. (664 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
BIRC2 | Baculoviral IAP repeat containing 2. (606 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2700 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
SEPTIN4-2 | Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (477 aa) | ||||
CTSH | Cathepsin H; Belongs to the peptidase C1 family. (335 aa) | ||||
BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (197 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (758 aa) | ||||
CASP2 | Caspase 2; Belongs to the peptidase C14A family. (452 aa) | ||||
MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (947 aa) | ||||
ITPR2 | Ion_trans domain-containing protein. (495 aa) | ||||
PARP3 | Poly [ADP-ribose] polymerase. (532 aa) | ||||
BIRC3 | Baculoviral IAP repeat containing 3. (603 aa) | ||||
G3SXI4_LOXAF | Uncharacterized protein. (895 aa) | ||||
TRADD | TNFRSF1A associated via death domain. (310 aa) | ||||
BIRC5 | Baculoviral IAP repeat containing 5. (140 aa) | ||||
CYCS | Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
CTSB | Cathepsin B; Belongs to the peptidase C1 family. (342 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa) | ||||
PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (974 aa) | ||||
DAB2IP | DAB2 interacting protein. (1189 aa) | ||||
CTSO | Cathepsin O; Belongs to the peptidase C1 family. (277 aa) | ||||
G3T189_LOXAF | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa) | ||||
BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3055 aa) | ||||
ERN1 | Endoplasmic reticulum to nucleus signaling 1. (955 aa) | ||||
AIFM1 | Apoptosis inducing factor mitochondria associated 1. (613 aa) | ||||
TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) | ||||
TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (973 aa) | ||||
GADD45A | Growth arrest and DNA damage inducible alpha. (146 aa) | ||||
MAPK1 | Mitogen-activated protein kinase. (329 aa) | ||||
RIPK1 | Receptor interacting serine/threonine kinase 1. (672 aa) | ||||
CASP7 | Caspase 7; Belongs to the peptidase C14A family. (265 aa) | ||||
MCL1 | MCL1 apoptosis regulator, BCL2 family member. (341 aa) | ||||
CTSS | Cathepsin S; Belongs to the peptidase C1 family. (342 aa) | ||||
PRF1 | Perforin 1. (555 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) | ||||
BCL2A1 | BCL2 related protein A1. (175 aa) | ||||
ATF4 | Activating transcription factor 4. (379 aa) | ||||
SPTA1 | Spectrin alpha, erythrocytic 1. (2392 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (466 aa) | ||||
FASLG | Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (277 aa) | ||||
G3TBD7_LOXAF | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa) | ||||
TNFSF10 | Tumor necrosis factor ligand superfamily member. (287 aa) | ||||
PTPN13 | Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. (2267 aa) | ||||
APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1246 aa) | ||||
CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (746 aa) | ||||
MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (403 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) | ||||
CASP9 | Caspase 9; Belongs to the peptidase C14A family. (450 aa) | ||||
CTSF | Cathepsin F; Belongs to the peptidase C1 family. (453 aa) | ||||
G3THD9_LOXAF | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (245 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) | ||||
DFFB | DNA fragmentation factor subunit beta. (340 aa) | ||||
LMNB1 | Lamin B1; Belongs to the intermediate filament family. (466 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
CASP8 | Caspase 8; Belongs to the peptidase C14A family. (478 aa) | ||||
HTRA2 | HtrA serine peptidase 2. (457 aa) | ||||
NFKBIA | NFKB inhibitor alpha. (314 aa) | ||||
NRAS | NRAS proto-oncogene, GTPase. (189 aa) | ||||
JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (329 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (509 aa) | ||||
CASP12 | Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (412 aa) | ||||
BAD | BCL2 associated agonist of cell death. (206 aa) | ||||
ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2670 aa) | ||||
EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1010 aa) | ||||
CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (488 aa) | ||||
PARP2 | Poly [ADP-ribose] polymerase. (569 aa) | ||||
IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (419 aa) | ||||
CASP3 | Caspase 3; Belongs to the peptidase C14A family. (281 aa) | ||||
G3TUP8_LOXAF | Uncharacterized protein; Belongs to the peptidase C1 family. (335 aa) | ||||
G3TVP2_LOXAF | Uncharacterized protein. (145 aa) | ||||
G3TW84_LOXAF | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (248 aa) | ||||
NGF | Nerve growth factor; Belongs to the NGF-beta family. (242 aa) | ||||
LOC100665585 | Uncharacterized protein; Belongs to the peptidase C1 family. (333 aa) | ||||
LOC104847000 | Peptidase S1 domain-containing protein. (225 aa) | ||||
PDPK1 | 3-phosphoinositide dependent protein kinase 1. (558 aa) | ||||
XIAP | X-linked inhibitor of apoptosis. (497 aa) | ||||
G3U0W1_LOXAF | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) | ||||
GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) | ||||
CTSD | Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (377 aa) | ||||
LOC100661985 | Uncharacterized protein; Belongs to the peptidase C1 family. (334 aa) | ||||
CTSK | Cathepsin K; Belongs to the peptidase C1 family. (330 aa) | ||||
EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) | ||||
PIK3R3 | Uncharacterized protein. (509 aa) | ||||
G3U6K2_LOXAF | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa) | ||||
CASP6 | Caspase 6; Belongs to the peptidase C14A family. (276 aa) | ||||
DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (428 aa) | ||||
IL3RA | Uncharacterized protein. (388 aa) | ||||
SPTAN1 | Spectrin alpha, non-erythrocytic 1. (2478 aa) | ||||
LOC100654286 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) | ||||
DIABLO | Uncharacterized protein. (237 aa) | ||||
CAPN1 | Calpain 1; Belongs to the peptidase C2 family. (703 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (431 aa) | ||||
G3UFG8_LOXAF | Fibronectin type-III domain-containing protein. (762 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (555 aa) | ||||
HRK | Harakiri, BCL2 interacting protein. (91 aa) | ||||
G3UJ54_LOXAF | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa) | ||||
TUBA1B | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa) | ||||
CAPN2 | Calpain 2; Belongs to the peptidase C2 family. (623 aa) | ||||
ENDOG | Endonuclease. (226 aa) | ||||
ACTG1 | Actin gamma 1. (379 aa) | ||||
G3ULI4_LOXAF | Uncharacterized protein; Belongs to the peptidase C14A family. (223 aa) | ||||
MAPK3 | Mitogen-activated protein kinase. (327 aa) |