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pyk pyk MTES_2016 MTES_2016 MTES_2014 MTES_2014 MTES_2001 MTES_2001 MTES_1964 MTES_1964 MTES_1918 MTES_1918 MTES_1915 MTES_1915 MTES_0006 MTES_0006 pgi pgi MTES_0019 MTES_0019 MTES_0052 MTES_0052 MTES_0114 MTES_0114 MTES_0116 MTES_0116 MTES_0119 MTES_0119 MTES_0127 MTES_0127 MTES_0204 MTES_0204 MTES_0212 MTES_0212 MTES_0220 MTES_0220 MTES_0221 MTES_0221 cmk cmk argB argB MTES_0332 MTES_0332 pfkA pfkA MTES_0363 MTES_0363 MTES_0367 MTES_0367 dhaK dhaK MTES_0396 MTES_0396 glpk glpk thrB thrB MTES_0439 MTES_0439 MTES_0441 MTES_0441 MTES_0456 MTES_0456 MTES_0496 MTES_0496 MTES_0518 MTES_0518 MTES_0527 MTES_0527 hldE hldE MTES_0592 MTES_0592 MTES_0593 MTES_0593 MTES_0608 MTES_0608 ptsI ptsI MTES_0706 MTES_0706 MTES_0721 MTES_0721 MTES_0819 MTES_0819 coaA coaA MTES_0840 MTES_0840 MTES_0846 MTES_0846 MTES_0852 MTES_0852 adk adk MTES_0929 MTES_0929 MTES_0967 MTES_0967 MTES_0988 MTES_0988 MTES_1025 MTES_1025 MTES_1043 MTES_1043 ldh ldh MTES_1076 MTES_1076 MTES_1078 MTES_1078 MTES_1128 MTES_1128 MTES_1139 MTES_1139 MTES_1166 MTES_1166 MTES_1187 MTES_1187 MTES_1197 MTES_1197 MTES_1210 MTES_1210 MTES_1235 MTES_1235 MTES_1291 MTES_1291 MTES_1292 MTES_1292 MTES_1323 MTES_1323 MTES_1369 MTES_1369 MTES_1458 MTES_1458 MTES_1476 MTES_1476 pknA pknA MTES_1492 MTES_1492 MTES_1525 MTES_1525 MTES_1536 MTES_1536 MTES_1549 MTES_1549 MTES_1586 MTES_1586 pdhB pdhB pdhC pdhC MTES_1786 MTES_1786 MTES_1792 MTES_1792 MTES_1796 MTES_1796 MTES_1890 MTES_1890 thiM thiM MTES_1899 MTES_1899 MTES_3674 MTES_3674 coaE coaE pgk pgk tpiA tpiA pgiA pgiA MTES_3613 MTES_3613 MTES_3612 MTES_3612 MTES_3573 MTES_3573 gmk gmk aroK aroK relA relA MTES_3498 MTES_3498 MTES_3457 MTES_3457 glk glk aceE aceE MTES_3425 MTES_3425 proB proB ndk ndk MTES_3299 MTES_3299 pyrH pyrH thiL thiL fruK fruK MTES_3154 MTES_3154 MTES_3150 MTES_3150 MTES_3121 MTES_3121 fba fba MTES_3012 MTES_3012 eno eno MTES_2965 MTES_2965 MTES_2961 MTES_2961 psrA psrA ispE ispE MTES_2911 MTES_2911 rbsK rbsK MTES_2850 MTES_2850 MTES_2813 MTES_2813 MTES_2762 MTES_2762 MTES_2738 MTES_2738 MTES_2729 MTES_2729 gpmA gpmA ppk ppk MTES_2682 MTES_2682 tmk tmk tdk tdk lysC lysC MTES_2631 MTES_2631 ackA ackA MTES_2565 MTES_2565 MTES_2520 MTES_2520 MTES_2252 MTES_2252 MTES_2240 MTES_2240 MTES_2231 MTES_2231 MTES_2227 MTES_2227 araB araB MTES_2212 MTES_2212 xylB xylB MTES_2202 MTES_2202 ppnK ppnK MTES_2153 MTES_2153 MTES_2149 MTES_2149 MTES_2111 MTES_2111 MTES_2103 MTES_2103 MTES_2078 MTES_2078 MTES_2068 MTES_2068
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pykPyruvate kinase; Belongs to the pyruvate kinase family. (481 aa)
MTES_2016Dihydroxyacetone kinase. (583 aa)
MTES_2014Triosephosphate isomerase. (255 aa)
MTES_2001Sugar. (507 aa)
MTES_1964Predicted kinase. (398 aa)
MTES_1918Uncharacterized protein. (415 aa)
MTES_1915Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. (619 aa)
MTES_0006Predicted unusual protein kinase. (564 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (571 aa)
MTES_0019Signal transduction histidine kinase. (322 aa)
MTES_0052Signal transduction histidine kinase. (372 aa)
MTES_0114Hypothetical protein. (114 aa)
MTES_0116Serine/threonine protein kinase. (649 aa)
MTES_0119Transcriptional regulator/sugar kinase. (311 aa)
MTES_0127FOG: FHA domain. (164 aa)
MTES_0204Signal transduction histidine kinase. (432 aa)
MTES_0212Signal transduction histidine kinase. (383 aa)
MTES_0220Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (330 aa)
MTES_0221Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component. (396 aa)
cmkCytidylate kinase. (257 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (300 aa)
MTES_0332Fructosamine-3-kinase. (253 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (342 aa)
MTES_0363FAD synthase; Belongs to the ribF family. (314 aa)
MTES_0367Predicted GTPase. (159 aa)
dhaKDihydroxyacetone kinase. (331 aa)
MTES_0396Dihydroxyacetone kinase. (212 aa)
glpkGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (503 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (310 aa)
MTES_0439Serine/threonine protein kinase. (376 aa)
MTES_0441ABC-type sugar transport systems, ATPase components. (369 aa)
MTES_0456Signal transduction histidine kinase. (391 aa)
MTES_0496Serine/threonine protein kinase. (653 aa)
MTES_0518Signal transduction histidine kinase. (498 aa)
MTES_0527Signal transduction histidine kinase. (563 aa)
hldEADP-heptose synthase, biproductal sugar kinase/adenylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (494 aa)
MTES_0592Uncharacterized conserved protein. (345 aa)
MTES_0593Signal transduction histidine kinase. (431 aa)
MTES_0608Phosphotransferase system cellobiose-specific component IIB. (115 aa)
ptsIPhosphoenolpyruvate-protein kinase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (565 aa)
MTES_0706Uncharacterized conserved protein. (211 aa)
MTES_0721Signal transduction histidine kinase. (391 aa)
MTES_0819Signal transduction histidine kinase. (305 aa)
coaAPanthothenate kinase. (314 aa)
MTES_0840Signal transduction histidine kinase, glucose-6-phosphate specific. (376 aa)
MTES_0846Predicted unusual protein kinase. (664 aa)
MTES_0852ATPase. (555 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (198 aa)
MTES_0929ATPase. (474 aa)
MTES_0967Serine/threonine protein kinase. (377 aa)
MTES_0988Signal transduction histidine kinase. (398 aa)
MTES_10254-aminobutyrate aminotransferase. (942 aa)
MTES_1043Sugar kinase, ribokinase family. (303 aa)
ldhMalate/lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (317 aa)
MTES_10767, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (175 aa)
MTES_1078Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (263 aa)
MTES_1128Sugar (pentulose and hexulose) kinase. (503 aa)
MTES_1139Putative regulator of cell autolysis. (390 aa)
MTES_1166Sugar kinase, ribokinase family. (309 aa)
MTES_1187Sugar kinase, ribokinase family. (310 aa)
MTES_1197Signal transduction histidine kinase. (543 aa)
MTES_1210Sugar kinase, ribokinase family. (308 aa)
MTES_1235Transcriptional regulator/sugar kinase. (403 aa)
MTES_1291Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family. (240 aa)
MTES_1292Signal transduction histidine kinase. (370 aa)
MTES_1323Uncharacterized conserved protein. (204 aa)
MTES_1369Osmosensitive K+ channel histidine kinase. (852 aa)
MTES_1458Signal transduction histidine kinase. (484 aa)
MTES_1476Predicted phosphatase. (233 aa)
pknASerine/threonine protein kinase. (575 aa)
MTES_1492Serine/threonine protein kinase. (576 aa)
MTES_1525Dolichyl-phosphate-mannose--protein O-mannosyl transferase. (363 aa)
MTES_1536Signal transduction histidine kinase. (367 aa)
MTES_1549Predicted aminoglycoside phosphotransferase. (301 aa)
MTES_1586Signal transduction histidine kinase. (359 aa)
pdhBPyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (325 aa)
pdhCPyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component. (444 aa)
MTES_1786Uncharacterized protein. (438 aa)
MTES_1792Hypothetical protein. (385 aa)
MTES_1796Signal transduction histidine kinase. (406 aa)
MTES_1890Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (484 aa)
thiMHydroxyethylthiazole kinase, sugar kinase family; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (273 aa)
MTES_1899Aminoglycoside phosphotransferase. (244 aa)
MTES_3674Signal transduction histidine kinase. (539 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (200 aa)
pgk3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (404 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (262 aa)
pgiAGlucose-6-phosphate isomerase; Belongs to the GPI family. (541 aa)
MTES_3613Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (333 aa)
MTES_3612Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component. (515 aa)
MTES_3573Serine/threonine protein kinase. (392 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (307 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (191 aa)
relAGuanosine polyphosphate pyrophosphohydrolase/synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (750 aa)
MTES_3498Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. (284 aa)
MTES_3457Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component. (570 aa)
glkTranscriptional regulator/sugar kinase. (261 aa)
aceEPyruvate dehydrogenase complex, dehydrogenase (E1) component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (908 aa)
MTES_3425Signal transduction histidine kinase. (474 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (278 aa)
ndkNucleoside diphosphate kinase. (138 aa)
MTES_3299Adenylate kinase. (197 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (239 aa)
thiLThiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (334 aa)
fruKFructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. (321 aa)
MTES_3154Hypothetical protein. (508 aa)
MTES_3150Uncharacterized protein, probably. (445 aa)
MTES_3121Predicted aminoglycoside phosphotransferase. (458 aa)
fbaFructose/tagatose bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (342 aa)
MTES_3012Signal transduction histidine kinase. (471 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
MTES_2965Gluconate kinase. (172 aa)
MTES_2961Signal transduction histidine kinase. (510 aa)
psrAPhosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (344 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (308 aa)
MTES_2911Signal transduction histidine kinase. (452 aa)
rbsKSugar kinase, ribokinase family; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (284 aa)
MTES_2850Glycerate kinase; Belongs to the glycerate kinase type-1 family. (368 aa)
MTES_2813Hypothetical protein. (528 aa)
MTES_2762Signal transduction histidine kinase. (564 aa)
MTES_2738Hypothetical protein. (440 aa)
MTES_2729Signal transduction histidine kinase. (405 aa)
gpmAPhosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (722 aa)
MTES_2682FOG: PAS/PAC domain. (370 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (224 aa)
tdkThymidine kinase. (201 aa)
lysCAspartokinase; Belongs to the aspartokinase family. (428 aa)
MTES_2631Serine/threonine protein kinase. (555 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (410 aa)
MTES_2565Sugar kinase, ribokinase family; Belongs to the carbohydrate kinase PfkB family. (313 aa)
MTES_2520Signal transduction histidine kinase. (380 aa)
MTES_2252ATPase. (507 aa)
MTES_2240Signal transduction histidine kinase regulating citrate/malate metabolism. (532 aa)
MTES_2231Glycerate kinase; Belongs to the glycerate kinase type-1 family. (368 aa)
MTES_2227Signal transduction histidine kinase regulating citrate/malate metabolism. (410 aa)
araBSugar (pentulose and hexulose) kinase. (533 aa)
MTES_2212Adenylate kinase. (185 aa)
xylBSugar (pentulose and hexulose) kinase. (463 aa)
MTES_2202Transcriptional regulator/sugar kinase. (386 aa)
ppnKPredicted sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (306 aa)
MTES_2153Signal transduction histidine kinase. (390 aa)
MTES_2149Signal transduction histidine kinase regulating citrate/malate metabolism. (537 aa)
MTES_2111Sphingosine kinase and enzyme. (429 aa)
MTES_2103Signal transduction histidine kinase. (714 aa)
MTES_2078Signal transduction histidine kinase. (542 aa)
MTES_2068Galactokinase; Belongs to the GHMP kinase family. GalK subfamily. (383 aa)
Your Current Organism:
Microbacterium testaceum
NCBI taxonomy Id: 979556
Other names: M. testaceum StLB037, Microbacterium testaceum StLB037, Microbacterium testaceum str. StLB037, Microbacterium testaceum strain StLB037
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