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MTES_1717 MTES_1717 MTES_1835 MTES_1835 MTES_1858 MTES_1858 MTES_1924 MTES_1924 MTES_1954 MTES_1954 mtnB mtnB MTES_2049 MTES_2049 MTES_2090 MTES_2090 MTES_2155 MTES_2155 MTES_2160 MTES_2160 recN recN MTES_2215 MTES_2215 MTES_2224 MTES_2224 MTES_2337 MTES_2337 MTES_2389 MTES_2389 MTES_2428 MTES_2428 rplJ rplJ rplL rplL MTES_2486 MTES_2486 MTES_2528 MTES_2528 MTES_2533 MTES_2533 recR recR MTES_2658 MTES_2658 MTES_2667 MTES_2667 MTES_2668 MTES_2668 topA topA MTES_2738 MTES_2738 MTES_2746 MTES_2746 MTES_2812 MTES_2812 MTES_2900 MTES_2900 MTES_2949 MTES_2949 MTES_2957 MTES_2957 rplY rplY MTES_2984 MTES_2984 MTES_3045 MTES_3045 MTES_3131 MTES_3131 rpmF rpmF smc smc MTES_3251 MTES_3251 rpsP rpsP rpsB rpsB MTES_3299 MTES_3299 MTES_3327 MTES_3327 rplU rplU obgE obgE MTES_3363 MTES_3363 MTES_3364 MTES_3364 rpsT rpsT MTES_3398 MTES_3398 recO recO dnaG dnaG pdxS pdxS MTES_3511 MTES_3511 MTES_3513 MTES_3513 priA-2 priA-2 MTES_3582 MTES_3582 MTES_3601 MTES_3601 rpmE2 rpmE2 cutC cutC MTES_1351 MTES_1351 MTES_1170 MTES_1170 MTES_1165 MTES_1165 recQ recQ MTES_1129 MTES_1129 MTES_1115 MTES_1115 MTES_1114 MTES_1114 MTES_1099 MTES_1099 MTES_1090 MTES_1090 rpsG rpsG rpsJ rpsJ rplC rplC rplW rplW rplB rplB rpsC rpsC rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsH rpsH rplR rplR rpsE rpsE rpmD rpmD rplO rplO rpsK rpsK rplQ rplQ rplM rplM rpsI rpsI rpmJ rpmJ MTES_0753 MTES_0753 MTES_0680 MTES_0680 MTES_0651 MTES_0651 hpf hpf MTES_0490 MTES_0490 MTES_0486 MTES_0486 MTES_0463 MTES_0463 MTES_0454 MTES_0454 MTES_0367 MTES_0367 rpsO rpsO rpmI rpmI rplT rplT parA-2 parA-2 MTES_0159 MTES_0159 nnrE nnrE parA parA MTES_0116 MTES_0116 MTES_0067 MTES_0067 MTES_0062 MTES_0062 MTES_0029 MTES_0029 MTES_0021 MTES_0021 rpsA rpsA MTES_1477 MTES_1477 MTES_1492 MTES_1492 gyrA gyrA gyrB gyrB recF recF rpmH rpmH parA-3 parA-3 parB parB MTES_1522 MTES_1522 rpsF rpsF rpsR rpsR dnaB dnaB MTES_1581 MTES_1581 MTES_1602 MTES_1602 MTES_1670 MTES_1670 rpmB rpmB rpmG rpmG rpsN rpsN hup hup
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTES_1717ABC-type sugar transport system, periplasmic component. (428 aa)
MTES_1835FOG: TPR repeat. (347 aa)
MTES_1858HhH-GPD family protein. (202 aa)
MTES_1924Hypothetical protein. (562 aa)
MTES_1954ABC-type sugar transport system, periplasmic component. (419 aa)
mtnBRibulose-5-phosphate 4-epimerase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (202 aa)
MTES_2049ABC-type sugar transport system, periplasmic component. (439 aa)
MTES_2090ABC-type sugar transport system, periplasmic component. (433 aa)
MTES_2155ABC-type sugar transport system, periplasmic component. (437 aa)
MTES_2160ABC-type sugar transport system, periplasmic component. (451 aa)
recNATPase; May be involved in recombinational repair of damaged DNA. (565 aa)
MTES_2215Ribulose-5-phosphate 4-epimerase. (238 aa)
MTES_2224ABC-type sugar transport system, periplasmic component. (427 aa)
MTES_2337ABC-type transport system. (337 aa)
MTES_2389Phytoene dehydrogenase. (526 aa)
MTES_2428MoxR-like ATPase. (523 aa)
rplJRibosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (171 aa)
rplLRibosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (128 aa)
MTES_2486ABC-type sugar transport system, periplasmic component. (442 aa)
MTES_2528Hypothetical protein. (343 aa)
MTES_2533Superfamily II RNA helicase. (843 aa)
recRRecombinational DNA repair protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (197 aa)
MTES_2658Predicted phosphohydrolase. (307 aa)
MTES_2667Flp pilus assembly protein, ATPase CpaF. (322 aa)
MTES_2668Flp pilus assembly protein TadB. (300 aa)
topATopoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superco [...] (904 aa)
MTES_2738Hypothetical protein. (440 aa)
MTES_2746Phytoene dehydrogenase. (473 aa)
MTES_2812FOG: TPR repeat. (869 aa)
MTES_2900Superfamily II DNA helicase. (548 aa)
MTES_2949ABC-type proline/glycine betaine transport systems, permease component. (252 aa)
MTES_2957Uncharacterized protein conserved in bacteria. (165 aa)
rplYRibosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (209 aa)
MTES_2984Carbonic anhydrase/acetyltransferase, isoleucine patch superfamily. (199 aa)
MTES_3045ADP-ribosylglycohydrolase. (317 aa)
MTES_3131Phytoene dehydrogenase. (518 aa)
rpmF50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (69 aa)
smcChromosome segregation ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1173 aa)
MTES_3251Hypothetical protein. (142 aa)
rpsPRibosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (138 aa)
rpsBRibosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (327 aa)
MTES_3299Adenylate kinase. (197 aa)
MTES_3327Carbonic anhydrase/acetyltransferase, isoleucine patch superfamily. (184 aa)
rplURibosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (102 aa)
obgEPredicted GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (514 aa)
MTES_3363Uncharacterized conserved protein; Belongs to the SOS response-associated peptidase family. (236 aa)
MTES_3364Uncharacterized conserved protein. (343 aa)
rpsTRibosomal protein S20; Binds directly to 16S ribosomal RNA. (86 aa)
MTES_3398Hypothetical protein. (181 aa)
recORecombinational DNA repair protein; Involved in DNA repair and RecF pathway recombination. (242 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (612 aa)
pdxSPyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (294 aa)
MTES_3511Hypothetical protein. (542 aa)
MTES_3513ATPase. (469 aa)
priA-2Primosomal protein N' (replication factor Y) - superfamily II helicase; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (660 aa)
MTES_3582Superfamily II RNA helicase. (827 aa)
MTES_3601NAD-dependent protein deacetylase, SIR2 family. (282 aa)
rpmE2Ribosomal protein L31. (83 aa)
cutCUncharacterized protein; Participates in the control of copper homeostasis. Belongs to the CutC family. (242 aa)
MTES_1351ABC-type sugar transport system, periplasmic component. (438 aa)
MTES_1170Topoisomerase IB. (321 aa)
MTES_1165Ribulose-5-phosphate 4-epimerase. (241 aa)
recQSuperfamily II DNA helicase. (678 aa)
MTES_1129Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (241 aa)
MTES_1115ABC-type sugar transport system, periplasmic component. (422 aa)
MTES_1114ABC-type sugar transport system, periplasmic component. (421 aa)
MTES_1099Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (415 aa)
MTES_1090DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. (464 aa)
rpsGRibosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsJRibosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rplCRibosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (219 aa)
rplWRibosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (99 aa)
rplBRibosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (279 aa)
rpsCRibosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (252 aa)
rpmCRibosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (103 aa)
rpsQRibosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (110 aa)
rplNRibosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rplXRibosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (119 aa)
rplERibosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (196 aa)
rpsHRibosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rplRRibosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (121 aa)
rpsERibosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (226 aa)
rpmDRibosomal protein L30/L7E. (61 aa)
rplORibosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (177 aa)
rpsKRibosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (132 aa)
rplQRibosomal protein L17. (186 aa)
rplMRibosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (148 aa)
rpsIRibosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (156 aa)
rpmJRibosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (40 aa)
MTES_0753Hypothetical protein. (532 aa)
MTES_0680Hypothetical protein. (243 aa)
MTES_0651Hypothetical protein. (213 aa)
hpfRibosome-associated protein Y (PSrp-1); Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (219 aa)
MTES_0490Hypothetical protein. (133 aa)
MTES_0486Short-chain alcohol dehydrogenase of unknown specificity. (256 aa)
MTES_0463Hypothetical protein. (679 aa)
MTES_0454Phytoene dehydrogenase. (493 aa)
MTES_0367Predicted GTPase. (159 aa)
rpsORibosomal protein S15P/S13E; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa)
rpmIRibosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (64 aa)
rplTRibosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (127 aa)
parA-2ATPase. (300 aa)
MTES_0159Uncharacterized protein conserved in bacteria. (1117 aa)
nnrEUncharacterized conserved protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. (256 aa)
parAATPase. (270 aa)
MTES_0116Serine/threonine protein kinase. (649 aa)
MTES_0067Uncharacterized protein, similar to the N-terminal domain of Lon protease. (217 aa)
MTES_0062DnaK suppressor protein. (113 aa)
MTES_0029Phytoene dehydrogenase. (411 aa)
MTES_0021Uncharacterized protein conserved in bacteria. (173 aa)
rpsA30S ribosomal protein S1. (484 aa)
MTES_1477Membrane-fusion protein. (399 aa)
MTES_1492Serine/threonine protein kinase. (576 aa)
gyrAType IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA stran [...] (876 aa)
gyrBType IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA stran [...] (677 aa)
recFRecombinational DNA repair ATPase; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (383 aa)
rpmHRibosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (45 aa)
parA-3ATPase. (305 aa)
parBPredicted transcriptional regulator; Belongs to the ParB family. (323 aa)
MTES_1522Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component. (723 aa)
rpsFRibosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (130 aa)
rpsRRibosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (84 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (455 aa)
MTES_1581Restriction endonuclease. (311 aa)
MTES_1602ABC-type sugar transport system, periplasmic component. (440 aa)
MTES_1670ABC-type sugar transport system, periplasmic component. (440 aa)
rpmBRibosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (78 aa)
rpmGRibosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (56 aa)
rpsNRibosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
hupBacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family. (95 aa)
Your Current Organism:
Microbacterium testaceum
NCBI taxonomy Id: 979556
Other names: M. testaceum StLB037, Microbacterium testaceum StLB037, Microbacterium testaceum str. StLB037, Microbacterium testaceum strain StLB037
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